Blar i Institutt for klinisk og molekylær medisin på emneord "VDP::Medical disciplines: 700"
Viser treff 21-40 av 119
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Clinical research in end-of-life cancer care Current status, barriers, priorities, and a framework for reporting a sample in clinical trials
(Doctoral thesis at NTNU;2014:355, Doctoral thesis, 2014)Kreft er en av de vanligste dødsårsakene i verden og den globale forekomsten øker. Mange pasienter som dør av kreft, har behov for palliative tiltak, men bare en liten andel av midlene til kreftforskning fordeles til ... -
Construction and evaluation of the performance of genetic risk scores for ankylosing spondylitis, rheumatoid arthritis, and myocardial infarction in the Norwegian population-based Nord- Trøndelag Health Study (HUNT)
(Doctoral theses at NTNU;2020:176, Doctoral thesis, 2020) -
Corticosteroids for Cancer Pain
(Doctoral theses at NTNU;2017:117, Doctoral thesis, 2017) -
Cytochrome P-450 (CYP) inhibition by commercial Rhodiola rosea products in vitro and in humans
(Doctoral theses at NTNU;2017:244, Doctoral thesis, 2017)Cytokrom P-450 (CYP) inhibering av kommersielle Rhodiola rosea produkter in vitro og i mennesker. Rosenrot (Rhodiola rosea) er et populært naturprodukt med en global utbredelse. Tidligere studier har vist at naturprodukter ... -
Cytosolic scaffold functions of PCNA
(Doctoral theses at NTNU;2017:203, Doctoral thesis, 2017)PCNA som et plattform-protein i cytosol Kroppen vår består av millioner av celler som alle stammer fra en enkelt celle. For hver celledeling må arvestoffet, DNA-et, kopieres feilfritt i et samarbeid mellom mange ulike ... -
Depression and Depressive Symptoms in Advanced Cancer Patients - Assessment, Classification and Treatment
(Doctoral thesis at NTNU;2015:199, Doctoral thesis, 2015)Summary in Norwegian: Depresjon og symptomer på depresjon – kartlegging, klassifisering og behandling Depresjon og depressive symptomer er en belastning for pasienter med langtkommen kreft. Anslag som er gjort av ... -
Development of non-injectable naloxone for pre-hospital reversal of opioid overdoses: A Norwegian project and a review of international status
(Master thesis, 2016)Background and aims: Per year, overdoses kill 69.000 users of illicit and prescription opioids in epidemic pattern worldwide. Among them, 250 people in Norway. Naloxone is an effective antidote for opioid overdose reversal, ... -
Development of strategies to identify new psychoactive substances and their metabolites in biological samples by LC-QTOF-MS technology
(Doctoral theses at NTNU;2020:303, Doctoral thesis, 2020)New psychoactive substances (NPS) are emerging in the illegal drug market, which has led to major challenges for analytical laboratories. Keeping screening methods up to date with all relevant drugs is hard to achieve and ... -
Dopamine D2 receptor C957T polymorphism and its phenotypic consequences on executive functions in 8 years old children
(Master thesis, 2015)Executive functions (EFs) are a set of cognitive skills that allows goal oriented behaviour. Three principal skills - inhibition, working memory and set-shifting - are thought to modulate higher level functions, such as ... -
Dynamics of base excision repair proteins; recruitment to replication forks and DNA lesions
(Doctoral theses at NTNU;2017:275, Doctoral thesis, 2017)DNA er arvestoffet vårt og finnes i de fleste celler i kroppen. DNA er satt sammen av to tråder bestående av sukkermolekyler, fosfat og nitrogenbaser (nukleotider). Disse kjemiske strukturene blir kontinuerlig utsatt for ... -
Effect of DHA on growth of two human colon cancer cell lines - the role of ER stress and unfolded protein response
(Master thesis, 2014)Docosahexaenoic acid (DHA; 22:6n-3) is an essential omega-3 polyunsaturated fatty acid important to human health. DHA has been shown to have anticancer properties by reducing cancer cell proliferation, inducing apoptosis ... -
Effects of cPLA2a inhibition in the MDA-MB-468 cell model system for basal-like breast cancer and/or triple negative breast cancer
(Master thesis, 2016)Basal-like breast cancer (BLBC) is a highly aggressive breast cancer sub-type and represents ~15% of all breast cancers. BLBC are often associated with early age of onset, early relapse and poor overall survival in contrast ... -
Effects of lost microRNA regulation at the global and single gene level in mammalian cells
(Doctoral thesis at NTNU;2014:307, Doctoral thesis, 2014) -
Epigenetic control of the intestinal epithelium A role for lysine-specific demethylase 1A during homeostasis and disease
(Doctoral theses at NTNU;2021:151, Doctoral thesis, 2021) -
Establishing tools to study the involvement of Keap1 in inflammatory signaling upon infection with M. avium
(Master thesis, 2015)Mycobacterium avium is a non-tuberculous mycobacteria that causes opportunistic infections in immunocompromised individuals such as AIDS patients. The pathogen is receiving more attention due to increasing resistance ... -
Establishment of methods for high throughput screening of nanoparticle toxicity in mammalian cells
(Master thesis, 2015)The use of nanomaterials is getting more extensive, both within the industrial and the medical field. The production and implementation of nanomaterials into consumer market is rapid and at such a rate that they are preceding ... -
Evaluation of the role of physical activity levels on the release of appetite-related hormones after preloads with a different energy content
(Master thesis, 2014)Background:Previous research has shown that regular exercisers are able to adjust their energy intake after preloads of different energy content, while inactive individuals are not. However, the mechanisms responsible ... -
Experimental-Computational Approaches to Identify Synergistic Effects of Anti-Cancer Drugs
(Doctoral theses at NTNU;2019:384, Doctoral thesis, 2019)Drug combinations are hoped to improve treatment response to anti-cancer drugs by targeting the cancers vulnerabilities at diverse trajectories. With a large number of approved agents of chemotherapeutic and targeted ... -
Exploring the role of TLR8 as a sensor in bacterial infections
(Doctoral theses at NTNU;2019:382, Doctoral thesis, 2019) -
Flow analysis of RANK expression on myeloid cells and identification of bone marrow cells expressing IL-32 in multiple myeloma patients
(Master thesis, 2016)Multiple myeloma is the second most common hematological cancer worldwide, characterized by an increased expansion of malignant plasma cells in the bone marrow, organ dysfunction, immunodeficiency and bone erosion. Nearly ...