Blar i Institutt for bioteknologi og matvitenskap på tittel
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Genome analysis of four novel Psychrobacter spp. and characterisation of their six putative laccase-like multicopper oxidases using bioinformatics tools
(Master thesis, 2015)In May 2009, several Psychrobacter spp. were found at the bottom of the Norwegian sea outside of Svalbard. Four of these, P11F6, P2G3, P11G3 and P11G5, were selected and sequenced for further work, and form the basis for ... -
Genome Copy Number Quantification Revealed That the Ethanologenic Alpha-Proteobacterium Zymomonas mobilis Is Polyploid
(Peer reviewed; Journal article, 2021)The alpha-proteobacterium Zymomonas mobilis is a promising biofuel producer, based on its native metabolism that efficiently converts sugars to ethanol. Therefore, it has a high potential for industrial-scale biofuel ... -
Genome Mining of actinomycete bacteria for new natural products
(Doctoral theses at NTNU;2018:348, Doctoral thesis, 2018)Here, the genome data of seven different strains of Streptomyces and a strain from the Actinoalloteichus genus were analysed for the presence of biosynthetic gene clusters (BGC) encoding for potential new natural products ... -
Genome Mining of Streptomyces sp. YIM 130001 Isolated From Lichen Affords New Thiopeptide Antibiotic
(Journal article; Peer reviewed, 2018)Streptomyces bacteria are recognized as an important source for antibiotics with broad applications in human medicine and animal health. Here, we report the isolation of a new lichen-associating Streptomyces sp. YIM 130001 ... -
Genome-based genetic tool development for Bacillus methanolicus: Theta-and rolling circle-replicating plasmids for inducible gene expression and application to methanol-based cadaverine production
(Peer reviewed; Journal article, 2016)Bacillus methanolicus is a thermophilic methylotroph able to overproduce amino acids from methanol, a substrate not used for human or animal nutrition. Based on our previous RNA-seq analysis a mannitol inducible promoter ... -
Genome-level transcription data of Yersinia pestis analyzed with a New metabolic constraint-based approach
(Journal article; Peer reviewed, 2012)Background: Constraint-based computational approaches, such as flux balance analysis (FBA), have proven successful in modeling genome-level metabolic behavior for conditions where a set of simple cellular objectives can ... -
Genome-scale constraint-based metabolic modeling and analysis of Nannochloropsis Sp.
(Master thesis, 2016)Genome scale metabolic models provide a link between genomic and metabolic information. The constraint-based approach is increasingly important for quantitatively analyzing the essential aspects of metabolic pathways, for ... -
Genome-scale metabolic modelling when changes in environmental conditions affect biomass composition
(Peer reviewed; Journal article, 2021)Genome-scale metabolic modeling is an important tool in the study of metabolism by enhancing the collation of knowledge, interpretation of data, and prediction of metabolic capabilities. A frequent assumption in the use ... -
Genome-scale metabolic models reveal determinants of phenotypic differences in non-Saccharomyces yeasts
(Peer reviewed; Journal article, 2023)Background - Use of alternative non-Saccharomyces yeasts in wine and beer brewing has gained more attention the recent years. This is both due to the desire to obtain a wider variety of flavours in the product and to reduce ... -
Genome-Scale Modeling of Embryonic Stem Cells
(Master thesis, 2023)Genom-skala metabolisk modellering har nylig blitt et sentralt verktøy innen bioteknologi. I denne masteroppgaven er målet å bruke rammeverket sMOMENT til å kombinere omics-data med en genom-skala metabolisk rekonstruksjon ... -
Genome-scale models and consequences of mass constraints and availability of enzymes
(Doctoral theses at NTNU;2021:294, Doctoral thesis, 2021)Genome-scale metabolic reconstructions offer a system-level view of metabolic networks with genetic basis and suggest mechanistic determination of cell's physiological homeostatic states. Consequently, they offer the ability ... -
Genome-scale reconstructions to assess metabolic phylogeny and organism clustering
(Peer reviewed; Journal article, 2020)Approaches for systematizing information of relatedness between organisms is important in biology. Phylogenetic analyses based on sets of highly conserved genes are currently the basis for the Tree of Life. Genome-scale ... -
Genomic and Transcriptomic Investigation of the Physiological Response of the Methylotroph Bacillus methanolicus to 5-Aminovalerate
(Peer reviewed; Journal article, 2021)The methylotrophic thermophile Bacillus methanolicus can utilize the non-food substrate methanol as its sole carbon and energy source. Metabolism of L-lysine, in particular its biosynthesis, has been studied to some detail, ... -
The genomic basis of the plant island syndrome in Darwin’s giant daisies
(Peer reviewed; Journal article, 2022)The repeated, rapid and often pronounced patterns of evolutionary divergence observed in insular plants, or the ‘plant island syndrome’, include changes in leaf phenotypes, growth, as well as the acquisition of a perennial ... -
Genomics of Sponge-Associated Streptomyces spp. Closely Related to Streptomyces albus J1074: Insights into Marine Adaptation and Secondary Metabolite Biosynthesis Potential
(Journal article; Peer reviewed, 2014)A total of 74 actinomycete isolates were cultivated from two marine sponges, Geodia barretti and Phakellia ventilabrum collected at the same spot at the bottom of the Trondheim fjord (Norway). Phylogenetic analyses of ... -
Genomics-based insights into the biosynthesis and unusually high accumulation of free fatty acids by Streptomyces sp. NP10
(Journal article; Peer reviewed, 2018)Streptomyces sp. NP10 was previously shown to synthesize large amounts of free fatty acids (FFAs). In this work, we report the first insights into the biosynthesis of these fatty acids (FAs) gained after genome sequencing ... -
Genotypic and Phenotypic Characterization of Norwegian Farmhouse Ale Yeast Cultures: A Domestication-Driven Evolution
(Master thesis, 2017)There is an immense gap in our knowledge regarding biodiversity of yeasts and the available untapped yeasts that can be found in nature. Studying both domesticated and wild species is important as it can enable us to better ... -
A glycan receptor kinase facilitates intracellular accommodation of arbuscular mycorrhiza and symbiotic rhizobia in the legume Lotus japonicus
(Peer reviewed; Journal article, 2023)Receptors that distinguish the multitude of microbes surrounding plants in the environment enable dynamic responses to the biotic and abiotic conditions encountered. In this study, we identify and characterise a glycan ... -
Gnotobiotic Atlantic cod larvae ( Gadus morhua L.) as a tool to study host-microbe interactions
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:364, Doctoral thesis, 2012)Atlantic cod (Gadus morhua L.) larvae hatch at an early developmental stage, and poor growth, high mortality and low reproducibility in juvenile production is considered the main bottleneck of cod farming. This high mortality ... -
Got Whey? Sustainability Endpoints for the Dairy Industry through Resource Biorecovery
(Peer reviewed; Journal article, 2023)Whey has applications in food, beverages, personal care products, pharmaceuticals, and the medical sector. However, it remains a massive dairy residue worldwide (160.7 million m3 year−1), with high organic and nutrient ...