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dc.contributor.authorKulmala, Maarit
dc.contributor.authorJørgensen, Anna Perregaard Munch
dc.contributor.authorAakvik, Kristina Anna Djupvik
dc.contributor.authorJussinniemi, Laura
dc.contributor.authorBenum, Silje Dahl
dc.contributor.authorIngvaldsen, Sigrid Hegna
dc.contributor.authorAusteng, Dordi Kristine
dc.contributor.authorKajantie, Eero Olavi
dc.contributor.authorEvensen, Kari Anne Indredavik
dc.contributor.authorMajander, Anna
dc.contributor.authorMorken, Tora Sund
dc.date.accessioned2024-07-05T09:05:01Z
dc.date.available2024-07-05T09:05:01Z
dc.date.created2023-05-26T11:15:49Z
dc.date.issued2023
dc.identifier.citationActa Ophthalmologica. 2023, 102 (1), 49-57.en_US
dc.identifier.issn1755-375X
dc.identifier.urihttps://hdl.handle.net/11250/3138500
dc.description.abstractPurpose: The purpose of the study was to investigate visual function and vision-related general health in adults that were born preterm with very low birth weight (VLBW: birth weight < 1500 g) in their 30s–40s. Methods: We recruited 137 adults born preterm with VLBW and 158 term-born controls aged 31–43 years from two birth cohorts: the Helsinki Study of Very Low Birth Weight Adults (Finland) and the NTNU Low Birth Weight in a Lifetime Perspective study (Norway). We used neonatal data and measured refraction, best-corrected visual acuity (BCVA) using the Early Treatment Diabetic Retinopathy Study (ETDRS) chart, contrast sensitivity, visual fields, intraocular pressure (IOP), self-reported vision-targeted health status with the National Eye Institute Visual Function Questionnaire-25. Results: VLBW adults had a lower BCVA ETDRS score than controls: mean (SD) better eye 86.7 (13.4) versus 90.2 (4.4), p = 0.02; mean (SD) worse eye 82.3 (14.9) versus 87.6 (4.6), p = 0.003. VLBW adults also had lower contrast sensitivity thresholds in several spatial frequencies and scored lower than controls in eight out of the 12 subscales of self-reported vision-targeted health status. Refraction, visual fields and IOP were similar between groups. Two VLBW participants were blind. None had been treated for retinopathy of prematurity. Conclusion: We suggest that lower visual function and vision-related health represent life-long consequences of prematurity and VLBW in the studied 31- to 43-year-old cohort. The underlying mechanisms remain to be determined.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleVisual function in adults born preterm with very low birth weight—A two-country birth cohort studyen_US
dc.title.alternativeVisual function in adults born preterm with very low birth weight—A two-country birth cohort studyen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.source.pagenumber49-57en_US
dc.source.volume102en_US
dc.source.journalActa Ophthalmologicaen_US
dc.source.issue1en_US
dc.identifier.doi10.1111/aos.15683
dc.identifier.cristin2149528
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal