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dc.contributor.authorGiri, Samita
dc.contributor.authorTronvik, Erling Andreas
dc.contributor.authorHagen, Knut
dc.date.accessioned2022-04-08T07:18:03Z
dc.date.available2022-04-08T07:18:03Z
dc.date.created2022-01-21T14:31:06Z
dc.date.issued2022
dc.identifier.issn1129-2369
dc.identifier.urihttps://hdl.handle.net/11250/2990662
dc.description.abstractBackground Few prospective population-based studies have evaluated the bidirectional relationship between headache and affective disorder. The aim of this large-scale population-based follow-up study was to investigate whether tension-type headache (TTH) and migraine had increased risk of developing anxiety and depression after 11 years, and vice-versa. Methods Data from the Trøndelag Health Study (HUNT) conducted in 2006-2008 (baseline) and 2017-2019 (follow-up) were used to evaluate the bidirectional relationship between migraine and TTH and anxiety and depression measured by Hospital Anxiety and depression Scale (HADS). The population at risk at baseline consisted of respectively 18,380 persons with HADS score ≤ 7 and 13,893 without headache, and the prospective data was analyzed by Poisson regression. Results In the multi-adjusted model, individuals with HADS anxiety (HADS-A) and depression scores (HADS-D) of ≥8 at baseline nearly doubled the risk of migraine (Risk rations (RR) between 1.8 and 2.2) at follow-up whereas a 40% increased risk (RR 1.4) was found for TTH. Vice versa, the risk of having HADS-A and HADS-D scores of ≥8 at follow-up were increased for TTH (RR 1.3) and migraine (RR 1.3-1.6) at baseline. Migraine with aura was associated with 81% (RR 1.81, 95% 1.52-2.14) increased risk of HADS-A score of ≥8. Conclusions In this large-scale population-based follow-up study we found a bidirectional relationship between anxiety and depression and migraine and TTH. For anxiety, this bidirectional association was slightly more evident for migraine than TTH.en_US
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.urihttps://thejournalofheadacheandpain.biomedcentral.com/track/pdf/10.1186/s10194-022-01388-x.pdf
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleThe bidirectional temporal relationship between headache and affective disorders: longitudinal data from the HUNT studiesen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.volume23en_US
dc.source.journalThe Journal of Headache and Painen_US
dc.source.issue14en_US
dc.identifier.doi10.1186/s10194-022-01388-x
dc.identifier.cristin1987468
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal