Now showing items 5340-5359 of 37304

    • Circularity evaluation as guidance for building design 

      Nemeth, Isabell; Schneider-Marin, Eva Patricia; Figl, Hildegund; Fellner, Maria; Asam, Claus (Peer reviewed; Journal article, 2022)
      Resource scarcity and global warming call for ambitious strategies in the construction sector to meet the ever-growing demand for indoor spaces with minimal resource consumption and positive environmental impacts. In line ...
    • Circulating and Adipose Tissue miRNAs in Women With Polycystic Ovary Syndrome and Responses to High-Intensity Interval Training 

      Lionett, Sofie Buurgaard; Kiel, Ida Almenning; Camera, Donny M; Vanky, Eszter; Parr, Evelyn B.; Lydersen, Stian; Hawley, John A; Moholdt, Trine (Peer reviewed; Journal article, 2020)
      MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally. In women with polycystic ovary syndrome (PCOS), several miRNAs are differentially expressed compared to women without PCOS, ...
    • Circulating concentrations of biomarkers and metabolites related to Vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations 

      Midttun, Øivind; Theofylaktopoulou, Despoina; Mccann, Adrian; Fanidi, Anouar; Muller, David C.; Meyer, Klaus; Ulvik, Arve; Zheng, Wei; Shu, Xiao-Ou; Xiang, Yong-Bing; Prentice, Ross; Thomson, Cynthia A.; Pettinger, Mary; Giles, Graham G.; Hodge, Allison; Cai, Qiuyin; Blot, William J.; Wu, Jie; Johansson, Mikael; Hultdin, Johan; Grankvist, Kjell; Stevens, Victoria L.; McCullough, Marjorie L.; Weinstein, Stephanie J.; Albanes, Demetrius; Langhammer, Arnulf; Hveem, Kristian; Næss, Marit; Sesso, Howard D.; Gaziano, J. Michael; Buring, Julie E.; Lee, I-Min; Severi, Gianluca; Zhang, Xuehong; Han, Jiali; Stampfer, Meir J.; Smith-Warner, Stephanie A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Yuan, Jian-Min; Butler, Lesley M.; Koh, Woon-Puay; Wang, Renwei; Gao, Yu-Tang; Ericson, Ulrika; Sonestedt, Emily; Ziegler, Regina G.; Freedman, Neal D.; Visvanathan, Kala; Jones, Miranda R.; Relton, Caroline; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Journal article; Peer reviewed, 2017)
      Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the ...
    • Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3) 

      Larose, Tricia L; Guida, Florence; Anouar, Fanidi; Langhammer, Arnulf; Hveem, Kristian; Stevens, Victoria L.; Jacobs, Eric J.; Smith-Warner, Stephanie A.; Giovannucci, Edward; Albanes, Demetrius; Weinstein, Stephanie J.; Freedman, Neal D.; Prentice, Ross; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Wilkens, Lynne R.; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J; Hodge, Allison M.; Giles, Graham G.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Wang, Renwei; Yuan, Jian-Min; Gao, Yu-Tang; Koh, Woon-Puay; Shu, Xiao-Ou; Zheng, Wei; Xiang, Yong-Bing; Li, Honglan; Lan, Qing; Visvanathan, Kala; Hoffman Bolton, Judith; Ueland, Per Magne; Midttun, Øivind; Caporaso, Neil; Purdue, Mark; Sesso, Howard D.; Buring, Julie E.; Lee, I-Min; Gaziano, J. Michael; Manjer, Jonas; Brunnström, Hans; Brennan, Paul; Johansson, Mattias (Journal article; Peer reviewed, 2018)
      Background Self-reported smoking is the principal measure used to assess lung cancer risk in epidemiological studies. We evaluated if circulating cotinine—a nicotine metabolite and biomarker of recent tobacco exposure—provides ...
    • Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer 

      Meltzer, Sebastian; Bjørnetrø, Tonje; Lyckander, Lars Gustav; Flatmark, Kjersti; Dueland, Svein; Samiappan, Rampradeep; Johansen, Christin; Kalanxhi, Ert; Ree, Anne Hansen; Redalen, Kathrine (Journal article; Peer reviewed, 2019)
      As many as 30% to 40% of locally advanced rectal cancer (LARC) patients experience metastatic progression of the disease. Recognizing the potential of the genetic cargo in tumor-derived exosomes, we hypothesized that plasma ...
    • Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia 

      Watts, Eleanor L.; Perez-Cornago, Aurora; Fensom, Georgina K.; Smith-Byrne, Karl; Noor, Urwah; Andrews, Colm D.; Gunter, Marc J.; Holmes, Michael V.; Martin, Richard M.; Tsilidis, Konstantinos K.; Albanes, Demetrius; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Chen, Chu; Cohn, Barbara A.; Dimou, Niki L.; Ferrucci, Luigi; Flicker, Leon; Freedman, Neal D.; Giles, Graham G.; Giovannucci, Edward L.; Goodman, Gary E.; Haiman, Christopher A.; Hankey, Graeme J.; Huang, Jiaqi; Huang, Wen-Yi; Hurwitz, Lauren M.; Kaaks, Rudolf; Knekt, Paul; Kubo, Tatsuhiko; Langseth, Hilde; Laughlin, Gail; Le Marchand, Loic; Luostarinen, Tapio; MacInnis, Robert J.; Mäenpää, Hanna O.; Männistö, Satu; Metter, E. Jeffrey; Mikami, Kazuya; Mucci, Lorelei A.; Olsen, Anja; Ozasa, Kotaro; Palli, Domenico; Penney, Kathryn L.; Platz, Elizabeth A.; Rissanen, Harri; Sawada, Norie; Schenk, Jeannette M.; Stattin, Pär; Tamakoshi, Akiko; Thysell, Elin; Tsai, Chiaojung Jillian; Tsugane, Shoichiro; Vatten, Lars Johan; Weiderpass, Elisabete; Weinstein, Stephanie J.; Wilkens, Lynne R.; Yeap, Bu B.; Allen, Naomi E.; Key, Timothy J.; Travis, Ruth C. (Peer reviewed; Journal article, 2022)
      Previous studies had limited power to assess the associations of testosterone with aggressive disease as a primary endpoint. Further, the association of genetically predicted testosterone with aggressive disease is not ...
    • Circulating high sensitivity C reactive protein concentrations and risk of lung cancer: Nested case-control study within Lung Cancer Cohort Consortium 

      Muller, David C.; Larose, Tricia L; Hodge, Allison; Guida, Florence; Langhammer, Arnulf; Grankvist, Kjell; Meyer, Klaus; Cai, Qiuyin; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Albanes, Demetrius; Giles, Graham G.; Sesso, Howard D.; Lee, I-Min; Gaziano, J. Michael; Yuan, Jian-Min; Hoffman Bolton, Judith; Buring, Julie E.; Visvanathan, Kala; Le Marchand, Loic; Purdue, Mark P.; Caporaso, Neil E.; Midttun, Øivind; Ueland, Per Magne; Prentice, Ross L.; Weinstein, Stephanie J.; Stevens, Victoria L.; Zheng, Wei; Blot, William J.; Shu, Xiao-Ou; Zhang, Xuehong; Xiang, Yong-Bing; Koh, Woon-Puay; Hveem, Kristian; Thomson, Cynthia A.; Pettinger, Mary; Engström, Gunnar; Brunnström, Hans; Milne, Roger L.; Stampfer, Meir J.; Han, Jiali; Johansson, Mikael; Brennan, Paul; Severi, Gianluca; Johansson, Mattias (Journal article; Peer reviewed, 2019)
      Objectives: Inflammation may play an important role in lung cancer pathogenesis. Previous studies have suggested an association between C-reactive protein (CRP) as a marker of inflammation, and risk of lung cancer, but ...
    • Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis 

      Bouras, Emmanouil; Karhunen, Ville; Gill, Dipender; Huang, Jian; Haycock, Philip C.; Gunter, Marc J.; Johansson, Mattias; Brennan, Paul; Key, Tim; Lewis, Sarah J.; Martin, Richard M.; Murphy, Neil; Platz, Elizabeth A.; Travis, Ruth; Yarmolinsky, James; Zuber, Verena; Martin, Paul; Katsoulis, Michail; Freisling, Heinz; Nøst, Therese Haugdahl; Schulze, Matthias B.; Dossus, Laure; Hung, Rayjean J.; Amos, Christopher I.; Ahola-Olli, Ari; Palaniswamy, Saranya; Männikkö, Minna; Auvinen, Juha; Herzig, Karl-Heinz; Keinänen-Kiukaanniemi, Sirkka; Lehtimäki, Terho; Salomaa, Veikko; Raitakari, Olli; Salmi, Marko; Jalkanen, Sirpa; Jarvelin, Marjo-Riitta; Dehghan, Abbas; Tsilidis, Konstantinos K. (Peer reviewed; Journal article, 2022)
      Background Epidemiological and experimental evidence has linked chronic inflammation to cancer aetiology. It is unclear whether associations for specific inflammatory biomarkers are causal or due to bias. In order to ...
    • Circulating Levels of Anti-C1q and Anti-Factor H Autoantibodies and Their Targets in Normal Pregnancy and Preeclampsia 

      Dijkstra, Douwe Jan; Lokki, A Inkeri; Gierman, Lobke; Borggreven, Nicole Veronique; van der Keur, Carin; Eikmans, Michael; Gelderman, Kyra Andrea; Laivuori, Hannele; Heinonen, Seppo; Kajantie, Eero Olavi; Kere, Juha; Kivinen, Katja; Pouta, Anneli; Iversen, Ann-Charlotte; van der Hoorn, Marie-Louise P; Trouw, Leendert Adrianus (Peer reviewed; Journal article, 2022)
      Preeclampsia (PE) generally manifests in the second half of pregnancy with hypertension and proteinuria. The understanding of the origin and mechanism behind PE is incomplete, although there is clearly an immune component ...
    • Circulating Levels of Inflammatory and Metabolic Biomarkers and Risk of Esophageal Adenocarcinoma and Barrett Esophagus: Systematic Review and Meta-analysis 

      Xie, Shao-hua; Rabbani, Sirus; Ness-Jensen, Eivind; Lagergren, Jesper (Peer reviewed; Journal article, 2020)
      Associations between circulating levels of obesity-related biomarkers and risk of esophageal adenocarcinoma and Barrett esophagus have been reported, but the results are inconsistent. A literature search until October 2018 ...
    • Circulating levels of micronutrients and risk of infections: a Mendelian randomization study 

      Flatby, Helene Marie; Ravi, Anuradha; Damås, Jan Kristian; Solligård, Erik; Rogne, Tormod (Peer reviewed; Journal article, 2023)
      Background Micronutrients play an essential role at every stage of the immune response, and deficiencies can therefore lead to increased susceptibility to infections. Previous observational studies and randomized ...
    • Circulating Lipoproteins in Subjects with Morbid Obesity Undergoing Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy 

      Aaseth, Jan; Rootwelt, Helge; Retterstøl, Kjetil; Hestad, Knut; Farup, Per Grønaas (Peer reviewed; Journal article, 2022)
      The efficacy of various bariatric procedures on the mitigation of the obese dyslipidemia remains debated, and the impact of these measures on lipoprotein(a) (Lp(a)) levels is unknown. In this study we aimed to compare the ...
    • Circulating markers of cellular immune activation in pre-diagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3) 

      Huang, Joyce Yongxu; Larose, Tricia L; Luu, Hung N; Wang, Renwei; Fanidi, Anouar; Alcala, Karine; Stevens, Victoria L.; Weinstein, Stephanie J.; Albanes, Demetrius; Caporaso, Neil E.; Purdue, Mark P.; Ziegler, Regina G.; Freedman, Neal D.; Lan, Qing; Prentice, Ross L.; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J.; Shu, Xiao-Ou; Zheng, Wei; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loïc; Wilkens, Lynn R; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J.; Han, Jiali; Giles, Graham G.; Hodge, Allison M.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Langhammer, Arnulf; Hveem, Kristian; Xiang, Yong-Bing; Li, Hong-Lan; Gao, Yu-Tang; Visvanathan, Kala; Ueland, Per Magne; Midttun, Øivind; Ulvik, Arve; Buring, Julie E.; Lee, I-Min; Sesso, Howard D.; Gaziano, J. Michael; Manjer, Jonas; Relton, Caroline; Koh, Woon-Puay; Brennan, Paul; Johansson, Mattias; Yuan, Jian-Min (Journal article; Peer reviewed, 2019)
      Cell‐mediated immune suppression may play an important role in lung carcinogenesis. We investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:tryptophan ratio (KTR), quinolinic acid (QA) ...
    • Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study 

      Rutkovskiy, Arkady; Lyngbakken, Magnus; Dahl, Mai Britt; Bye, Anja; Pedersen, Marit Holmefjord; Wisløff, Ulrik; Christensen, Geir Arve; Høiseth, Arne Didrik; Omland, Torbjørn; Røsjø, Helge (Peer reviewed; Journal article, 2021)
      Background MicroRNA (miR)-210 expression is induced by acute and chronic hypoxia and provides prognostic information in patients with aortic stenosis and acute coronary syndrome. We hypothesized that circulating miR-210 ...
    • Circulating MicroRNAs and Aerobic Fitness - The HUNT-Study 

      Bye, Anja; Røsjø, Helge; Aspenes, Stian Thoresen; Condorelli, Gianluigi; Omland, Torbjørn; Wisløff, Ulrik (Journal article; Peer reviewed, 2013)
      Aerobic fitness, measured as maximal oxygen uptake (VO2max), is a good indicator of cardiovascular health, and a strong predictor of cardiovascular mortality. Biomarkers associated with low VO2max may therefore represent ...
    • Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study. 

      Velle-Forbord, Torbjørn; Eidlaug, Maria; Debik, Julia Barbara; Sæther, Julie Caroline; Follestad, Turid; Nauman, Javaid; Gigante, Bruna; Røsjø, Helge; Omland, Torbjørn; Langaas, Mette; Bye, Anja (Peer reviewed; Journal article, 2019)
      Background and aims Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have recently been ...
    • Circulating microRNAs May Serve as Biomarkers for Hypertensive Emergency End-Organ Injuries and Address Underlying Pathways in an Animal Model 

      Langlo, Knut Asbjørn Rise; Silva, Gustavo Jose Justo; Overrein, Tina Syvertsen; Adams, Volker; Wisløff, Ulrik; Dalen, Håvard; Rolim, Natale Pinheiro Lage; Hallan, Stein (Journal article; Peer reviewed, 2021)
      There is an incomplete understanding of the underlying pathophysiology in hypertensive emergencies, where severely elevated blood pressure causes acute end-organ injuries, as opposed to the long-term manifestations of ...
    • Circulating Sex Hormone Levels and Risk of Esophageal Adenocarcinoma in a Prospective Study in Men 

      Xie, Shao-Hua; Ness-Jensen, Eivind; Rabbani, Sirus; Langseth, Hilde; Gislefoss, Randi Elin; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)
      OBJECTIVES: Sex hormones have been hypothesized to explain the strong male predominance in esophageal adenocarcinoma, but evidence is needed. This study examined how circulating sex hormone levels influence future risk of ...
    • Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men 

      Watts, Eleanor L.; Appleby, Paul N.; Albanes, Demetrius; Black, Amanda; Chan, June M.; Chen, Chu; Cirillo, Piera M.; Cohn, Barbara A.; Cook, Michael B.; Donovan, Jenny L.; Ferrucci, Luigi; Garland, Cedric F.; Giles, Graham G.; Goodman, Phyllis J.; Habel, Laurel A.; Haiman, Christopher A.; Holly, Jeff M.P.; Hoover, Robert N.; Kaaks, Rudolf; Knekt, Paul; Kolonel, Laurence N.; Kubo, Tatsuhiko; Le Marchand, Loïc; Luostarinen, Tapio; MacInnis, Robert J.; Mäenpää, Hanna O.; Männistö, Satu; Metter, E. Jeffrey; Milne, Roger L.; Nomura, Abraham M.Y.; Oliver, Steven E.; Parsons, J. Kellogg; Peeters, Petra H.; Platz, Elizabeth A.; Riboli, Elio; Ricceri, Fulvio; Rinaldi, Sabina; Rissanen, Harri; Sawada, Norie; Schaefer, Catherine A.; Schenk, Jeannette M.; Stanczyk, Frank Z.; Stampfer, Meir; Stattin, Pär; Stenman, Ulf-Håkan; Tjønneland, Anne; Trichopoulou, Antonia; Thompson, Ian M.; Tsugane, Shoichiro; Vatten, Lars Johan; Whittemore, Alice S.; Ziegler, Regina G.; Allen, Naomi E.; Key, Timothy J.; Travis, Ruth C. (Journal article; Peer reviewed, 2017)
      Introduction Sex hormones have been implicated in the etiology of a number of diseases. To better understand disease etiology and the mechanisms of disease-risk factor associations, this analysis aimed to investigate the ...
    • The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer 

      Meltzer, Sebastian; Kristensen, Annette Torgunrud; Abrahamsson, Hanna Josefine; Solbakken, Arne Mide; Flatmark, Kjersti; Dueland, Svein; Bakke, Kine Mari; Bousquet, Paula; Negård, Anne; Johansen, Christin; Lyckander, Lars Gustav; Larsen, Finn Ole; Schou, Jakob Vasehus; Redalen, Kathrine; Ree, Anne Hansen (Peer reviewed; Journal article, 2021)
      Background In colorectal cancer, the inflamed tumour microenvironment with its angiogenic activities is immune- tolerant and incites progression to liver metastasis. We hypothesised that angiogenic and inflammatory factors ...