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    • Circulating Levels of Anti-C1q and Anti-Factor H Autoantibodies and Their Targets in Normal Pregnancy and Preeclampsia 

      Dijkstra, Douwe Jan; Lokki, A Inkeri; Gierman, Lobke; Borggreven, Nicole Veronique; van der Keur, Carin; Eikmans, Michael; Gelderman, Kyra Andrea; Laivuori, Hannele; Heinonen, Seppo; Kajantie, Eero Olavi; Kere, Juha; Kivinen, Katja; Pouta, Anneli; Iversen, Ann-Charlotte; van der Hoorn, Marie-Louise P; Trouw, Leendert Adrianus (Peer reviewed; Journal article, 2022)
      Preeclampsia (PE) generally manifests in the second half of pregnancy with hypertension and proteinuria. The understanding of the origin and mechanism behind PE is incomplete, although there is clearly an immune component ...

    • Circulating Levels of Inflammatory and Metabolic Biomarkers and Risk of Esophageal Adenocarcinoma and Barrett Esophagus: Systematic Review and Meta-analysis 

      Xie, Shao-hua; Rabbani, Sirus; Ness-Jensen, Eivind; Lagergren, Jesper (Peer reviewed; Journal article, 2020)
      Associations between circulating levels of obesity-related biomarkers and risk of esophageal adenocarcinoma and Barrett esophagus have been reported, but the results are inconsistent. A literature search until October 2018 ...

    • Circulating levels of micronutrients and risk of infections: a Mendelian randomization study 

      Flatby, Helene Marie; Ravi, Anuradha; Damås, Jan Kristian; Solligård, Erik; Rogne, Tormod (Peer reviewed; Journal article, 2023)
      Background Micronutrients play an essential role at every stage of the immune response, and deficiencies can therefore lead to increased susceptibility to infections. Previous observational studies and randomized ...

    • Circulating Lipoproteins in Subjects with Morbid Obesity Undergoing Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy 

      Aaseth, Jan; Rootwelt, Helge; Retterstøl, Kjetil; Hestad, Knut; Farup, Per Grønaas (Peer reviewed; Journal article, 2022)
      The efficacy of various bariatric procedures on the mitigation of the obese dyslipidemia remains debated, and the impact of these measures on lipoprotein(a) (Lp(a)) levels is unknown. In this study we aimed to compare the ...

    • Circulating markers of cellular immune activation in pre-diagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3) 

      Huang, Joyce Yongxu; Larose, Tricia L; Luu, Hung N; Wang, Renwei; Fanidi, Anouar; Alcala, Karine; Stevens, Victoria L.; Weinstein, Stephanie J.; Albanes, Demetrius; Caporaso, Neil E.; Purdue, Mark P.; Ziegler, Regina G.; Freedman, Neal D.; Lan, Qing; Prentice, Ross L.; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J.; Shu, Xiao-Ou; Zheng, Wei; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loïc; Wilkens, Lynn R; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J.; Han, Jiali; Giles, Graham G.; Hodge, Allison M.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Langhammer, Arnulf; Hveem, Kristian; Xiang, Yong-Bing; Li, Hong-Lan; Gao, Yu-Tang; Visvanathan, Kala; Ueland, Per Magne; Midttun, Øivind; Ulvik, Arve; Buring, Julie E.; Lee, I-Min; Sesso, Howard D.; Gaziano, J. Michael; Manjer, Jonas; Relton, Caroline; Koh, Woon-Puay; Brennan, Paul; Johansson, Mattias; Yuan, Jian-Min (Journal article; Peer reviewed, 2019)
      Cell‐mediated immune suppression may play an important role in lung carcinogenesis. We investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:tryptophan ratio (KTR), quinolinic acid (QA) ...

    • Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study 

      Rutkovskiy, Arkady; Lyngbakken, Magnus; Dahl, Mai Britt; Bye, Anja; Pedersen, Marit Holmefjord; Wisløff, Ulrik; Christensen, Geir Arve; Høiseth, Arne Didrik; Omland, Torbjørn; Røsjø, Helge (Peer reviewed; Journal article, 2021)
      Background MicroRNA (miR)-210 expression is induced by acute and chronic hypoxia and provides prognostic information in patients with aortic stenosis and acute coronary syndrome. We hypothesized that circulating miR-210 ...

    • Circulating MicroRNAs and Aerobic Fitness - The HUNT-Study 

      Bye, Anja; Røsjø, Helge; Aspenes, Stian Thoresen; Condorelli, Gianluigi; Omland, Torbjørn; Wisløff, Ulrik (Journal article; Peer reviewed, 2013)
      Aerobic fitness, measured as maximal oxygen uptake (VO2max), is a good indicator of cardiovascular health, and a strong predictor of cardiovascular mortality. Biomarkers associated with low VO2max may therefore represent ...

    • Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study. 

      Velle-Forbord, Torbjørn; Eidlaug, Maria; Debik, Julia Barbara; Sæther, Julie Caroline; Follestad, Turid; Nauman, Javaid; Gigante, Bruna; Røsjø, Helge; Omland, Torbjørn; Langaas, Mette; Bye, Anja (Peer reviewed; Journal article, 2019)
      Background and aims Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have recently been ...

    • Circulating microRNAs May Serve as Biomarkers for Hypertensive Emergency End-Organ Injuries and Address Underlying Pathways in an Animal Model 

      Langlo, Knut Asbjørn Rise; Silva, Gustavo Jose Justo; Overrein, Tina Syvertsen; Adams, Volker; Wisløff, Ulrik; Dalen, Håvard; Rolim, Natale Pinheiro Lage; Hallan, Stein (Journal article; Peer reviewed, 2021)
      There is an incomplete understanding of the underlying pathophysiology in hypertensive emergencies, where severely elevated blood pressure causes acute end-organ injuries, as opposed to the long-term manifestations of ...

    • Circulating Sex Hormone Levels and Risk of Esophageal Adenocarcinoma in a Prospective Study in Men 

      Xie, Shao-Hua; Ness-Jensen, Eivind; Rabbani, Sirus; Langseth, Hilde; Gislefoss, Randi Elin; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)
      OBJECTIVES: Sex hormones have been hypothesized to explain the strong male predominance in esophageal adenocarcinoma, but evidence is needed. This study examined how circulating sex hormone levels influence future risk of ...

    • Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men 

      Watts, Eleanor L.; Appleby, Paul N.; Albanes, Demetrius; Black, Amanda; Chan, June M.; Chen, Chu; Cirillo, Piera M.; Cohn, Barbara A.; Cook, Michael B.; Donovan, Jenny L.; Ferrucci, Luigi; Garland, Cedric F.; Giles, Graham G.; Goodman, Phyllis J.; Habel, Laurel A.; Haiman, Christopher A.; Holly, Jeff M.P.; Hoover, Robert N.; Kaaks, Rudolf; Knekt, Paul; Kolonel, Laurence N.; Kubo, Tatsuhiko; Le Marchand, Loïc; Luostarinen, Tapio; MacInnis, Robert J.; Mäenpää, Hanna O.; Männistö, Satu; Metter, E. Jeffrey; Milne, Roger L.; Nomura, Abraham M.Y.; Oliver, Steven E.; Parsons, J. Kellogg; Peeters, Petra H.; Platz, Elizabeth A.; Riboli, Elio; Ricceri, Fulvio; Rinaldi, Sabina; Rissanen, Harri; Sawada, Norie; Schaefer, Catherine A.; Schenk, Jeannette M.; Stanczyk, Frank Z.; Stampfer, Meir; Stattin, Pär; Stenman, Ulf-Håkan; Tjønneland, Anne; Trichopoulou, Antonia; Thompson, Ian M.; Tsugane, Shoichiro; Vatten, Lars Johan; Whittemore, Alice S.; Ziegler, Regina G.; Allen, Naomi E.; Key, Timothy J.; Travis, Ruth C. (Journal article; Peer reviewed, 2017)
      Introduction Sex hormones have been implicated in the etiology of a number of diseases. To better understand disease etiology and the mechanisms of disease-risk factor associations, this analysis aimed to investigate the ...

    • The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer 

      Meltzer, Sebastian; Kristensen, Annette Torgunrud; Abrahamsson, Hanna Josefine; Solbakken, Arne Mide; Flatmark, Kjersti; Dueland, Svein; Bakke, Kine Mari; Bousquet, Paula; Negård, Anne; Johansen, Christin; Lyckander, Lars Gustav; Larsen, Finn Ole; Schou, Jakob Vasehus; Redalen, Kathrine; Ree, Anne Hansen (Peer reviewed; Journal article, 2021)
      Background In colorectal cancer, the inflamed tumour microenvironment with its angiogenic activities is immune- tolerant and incites progression to liver metastasis. We hypothesised that angiogenic and inflammatory factors ...

    • Circulating trace elements: Comparison between early and late incubation in common eiders (Somateria mollissima) in the central Baltic Sea 

      Mcpartland, Molly; Noori, Brenley; Garbus, Svend-Erik; Lierhagen, Syverin; Sonne, Christian; Krøkje, Åse (Peer reviewed; Journal article, 2020)
      We analyzed body mass and a panel of 64 trace elements in blood from incubating common eiders (Somateria mollissima) in the central Baltic Sea during the breeding seasons of 2017 (n = 27) and 2018 (n = 23). Using a ...

    • Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study 

      Langeland, Halvor; Langeland, Halvor; Bergum, Daniel; Nordseth, Trond; Løberg, Magnus; Skaug, Thomas; Skaug, Thomas Renhult; Bjørnstad, Knut; Bjørnstad, Knut; Gundersen, Ørjan; Skjaervold, Nils Kristian; Klepstad, Pål (Peer reviewed; Journal article, 2021)
      Background: Circulatory failure frequently occurs after out-of-hospital cardiac arrest (OHCA) and is part of postcardiac arrest syndrome (PCAS). The aim of this study was to investigate circulatory disturbances in PCAS by ...

    • Circum-Arctic distribution of chemical anti-herbivore compounds suggests biome-wide trade-off in defence strategies in Arctic shrubs 

      Lindén, Elin; te Beest, Mariska; Aubreu, Ilka; Moritz, Thomas; Sundqvist, Maja K.; Barrio, Isabel C.; Boike, Julia; Bryant, John P.; Bråthen, Kari Anne; Buchwal, Agata; Bueno, C. Guillermo; Currier, Alain; Egelkraut, Dagmar Dorothea; Forbes, Bruce C.; Hallinger, Martin; Heijmans, Monique; Hermanutz, Luise; Hik, David S.; Hofgaard, Annika; Holmgren, Milena; Huebner, Diane C.; Høye, Toke T.; Jónsdóttir, Ingibjörg S.; Kaarlejärvi, Elina; Kissler, Emilie; Kumpula, Timo; Limpens, Juul; Myers-Smith, Isla H.; Normand, Signe; Post, Eric; Rocha, Adrian V.; Schmidt, Niels Martin; Skarin, Anna; Soininen, Eeva M; Sokolov, Aleksandr; Sokolova, Natalia; Speed, James David Mervyn; Street, Lorna E.; Tananaev, Nikita; Tremblay, Jean-Pierre; Urbanowicz, Christine; Watts, David A.; Zimmermann, Heike H.; Olofsson, Johan (Peer reviewed; Journal article, 2022)
      Spatial variation in plant chemical defence towards herbivores can help us understand variation in herbivore top–down control of shrubs in the Arctic and possibly also shrub responses to global warming. Less defended, ...

    • Circumpolar dynamics of a marine top-predator track ocean warming rates 

      Descamps, Sebastian; Anker-Nilssen, Tycho; Barrett, Robert T; Irons, D; Merkel, Flemming; Robertson, Gregory J.; Yoccoz, Nigel Gilles; Mallory, Mark L; Montevecchi, William A.; Boertmann, D.; Artukhin, Yuri; Christensen-Dalsgaard, Signe; Erikstad, Kjell E; Gilchrist, H. Grant; Labansen, Aili; Lorentsen, Svein Håkon; Mosbech, Anders; Olsen, Bergur; Petersen, Aevar; Rail, Jean-Francois; Renner, Heather M.; Strøm, H.; Systad, Geir Helge; Wilhelm, Sabina I.; Zelenskaya, Larisa (Journal article; Peer reviewed, 2017)
      Global warming is a nonlinear process, and temperature may increase in a stepwise manner. Periods of abrupt warming can trigger persistent changes in the state of ecosystems, also called regime shifts. The responses of ...

    • CIRLEM: a synergic integration of Collective Intelligence and Reinforcement learning in Energy Management for enhanced climate resilience and lightweight computation 

      Nik, Vahid m.; Hosseini, Mohammad (Peer reviewed; Journal article, 2023)
      A novel energy management (EM) approach is introduced, integrating core elements of collective intelligence (CI) and reinforcement learning (RL) and called CIRLEM. It operates by distributing a flexibility signal from the ...

    • Citizen participation in Steinkjer: Stories about the "old NRK building at Lø" 

      Woods, Ruth; Berker, Thomas (Peer reviewed; Journal article, 2020)
      This paper follows the process of developing a pilot project at Lø in Steinkjer, where a zero emission neighbourhood was planned and which included the upgrading of the old offices of the Norwegian Broadcasting Company ...

    • Citizen Participation: Linking Government Efforts, Actual Participation, and Trust in Local Politicians 

      Holum, Marthe (Peer reviewed; Journal article, 2022)
      The present study analyzes several aspects of the relationship between citizen participation and trust employing data from Norwegian municipalities: first, the impact of local government efforts to increase participation ...

    • Citizen Sensing Stakeholder Interaction Manual 

      Wilk, Julie; Neset, Tina-Simone; Andersson, Lotta; Conceição, Paulo; Gonçalves, Paula; Graça, Marisa; Maarse, Maaike J.; Malafaya, Filipa; Opach, Tomasz; Monteiro, Ana; Rød, Jan Ketil; Cruz, Sara Santos; Wikner, Jacob J.; Zijderveld, Annette (Research report, 2021)