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Intracellular pHluorin as Sensor for Easy Assessment of Bacteriocin-Induced Membrane-Damage in Listeria monocytogenes
(Journal article; Peer reviewed, 2018)Bacteriocins are antimicrobial peptides naturally produced by many bacteria and were shown to be effective against various pathogens including Listeria monocytogenes. L. monocytogenes is a food-borne pathogen that frequently ... -
Intracranial effect of osimertinib in relapsed EGFR-mutated T790M-positive and -negative non-small cell lung cancer patients: results from a phase II study
(Peer reviewed; Journal article, 2021)Introduction Osimertinib is effective for relapsed T790M-positive patients with brain metastases. The high brain permeability suggests that also such patients without T790M could benefit. Therefore, we evaluated the effect ... -
Intraday Electricity Pricing of Night Contracts
(Peer reviewed; Journal article, 2020)This paper investigates the intraday electricity pricing of 15-min. contracts in night hours. We tailor a recently introduced econometric model with fundamental impacts, which is successful in describing the pricing of day ... -
Intranasal analgesia for acute moderate to severe pain in children – a systematic review and meta-analysis
(Peer reviewed; Journal article, 2023)Background Children in acute pain often receive inadequate pain relief, partly from difficulties administering injectable analgesics. A rapid-acting, intranasal (IN) analgesic may be an alternative to other parenteral ... -
Intraoperative 3D ultrasound-guided resection of diffuse low-grade gliomas: radiological and clinical results
(Peer reviewed; Journal article, 2019)OBJECTIVE Extent of resection (EOR) and residual tumor volume are linked to prognosis in low-grade glioma (LGG) and there are various methods for facilitating safe maximal resection in such patients. In this prospective ... -
Intraoperative Data-Based Haptic Feedback for Arthroscopic Partial Meniscectomy Punch Simulation
(Peer reviewed; Journal article, 2022)The use of intraoperative tool-tissue interaction data for arthroscopic digital twins has the potential to enhance haptic feedback in surgical simulations. This study demonstrates the implementation of an interpolation-based ... -
Intraoperative localized constrained registration in navigated bronchoscopy
(Journal article; Peer reviewed, 2017)Purpose One of the major challenges in electromagnetic navigated bronchoscopy is the navigation accuracy. An initial rigid image-to-patient registration may not be optimal for the entire lung volume, as the lung tissue ... -
Intraoperative risk factors for peritumoral infarctions following glioma surgery
(Peer reviewed; Journal article, 2022)Background Surgical intraoperative risk factors for peritumoral infarctions are not much studied. In the present study, we explore the possible association between intraoperative factors and infarctions diagnosed from ... -
Intraoperatively local infiltration anesthesia in hemiarthroplasty patients reduces the needs of opioids: a randomized, double-blind, placebo-controlled trial with 96 patients in a fast-track hip fracture setting
(Peer reviewed; Journal article, 2022)Background and purpose — Local infiltration analgesia (LIA) is commonly used as a component in multimodal analgesia. Pain management directed towards hip fracture patients operated on with hemiarthroplasty is often based ... -
Intrapartum ultrasound assessment of cervical dilatation and its value in detecting active labor
(Peer reviewed; Journal article, 2018)Introduction We aimed to examine the agreement between ultrasound and digital vaginal examination in assessing cervical dilatation in an African population and to assess the value of ultrasound in detecting active ... -
Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
(Peer reviewed; Journal article, 2023)Colorectal and ovarian cancers frequently develop peritoneal metastases with few treatment options. Intraperitoneal chemotherapy has shown promising therapeutic effects, but is limited by rapid drug clearance and systemic ... -
Intraperitoneal and subcutaneous glucagon delivery in anaesthetized pigs: effects on circulating glucagon and glucose levels
(Journal article; Peer reviewed, 2020)Glucagon is a pancreatic hormone and increases the blood glucose levels. It may be incorporated in a dual hormone artificial pancreas, a device to automatically and continuously control blood glucose levels of individuals ... -
Intraperitoneal insulin administration in pigs: Effect on circulating insulin and glucose levels
(Peer reviewed; Journal article, 2021)Introduction The effect of intraperitoneal insulin infusion has limited evidence in the literature. Therefore, the aim of the study was to investigate the pharmacokinetics and pharmacodynamics of different intraperitoneal ... -
Intraperitoneal, subcutaneous and intravenous glucagon delivery and subsequent glucose response in rats: A randomized controlled crossover trial
(Journal article; Peer reviewed, 2018)Objective Hypoglycemia is a frequent and potentially dangerous event among patients with diabetes mellitus type 1. Subcutaneous glucagon is an emergency treatment to counteract severe hypoglycemia. The effect of intraperitoneal ... -
Intraspecific trait variability is a key feature underlying high Arctic plant community resistance to climate warming
(Peer reviewed; Journal article, 2022)In the high Arctic, plant community species composition generally responds slowly to climate warming, whereas less is known about the community functional trait responses and consequences for ecosystem functioning. The ... -
Intrauterine Growth and Offspring Neurodevelopmental Traits A Mendelian Randomization Analysis of the Norwegian Mother, Father and Child Cohort Study (MoBa)
(Journal article; Peer reviewed, 2023)Importance Conventional epidemiological analyses have suggested that lower birth weight is associated with later neurodevelopmental difficulties; however, it is unclear whether this association is causal. Objective ... -
Intravascular Targets for Molecular Contrast-Enhanced Ultrasound Imaging
(Journal article; Peer reviewed, 2012)Molecular targeting of contrast agents for ultrasound imaging is emerging as a new medical imaging modality. It combines advances in ultrasound technology with principles of molecular imaging, thereby allowing non-invasive ... -
Intravenous Iron Treatment in the Prevention of Iron Deficiency and Anaemia After Roux-en-Y Gastric Bypass
(Peer reviewed; Journal article, 2020)Background Iron absorption is disturbed after Roux-en-Y gastric bypass (RYGB) and iron deficiency with or without anaemia affects almost half of all patients. Intravenous iron is an option when per oral iron is insufficient ... -
Intraventricular Vector Flow Imaging with Blood Speckle Tracking in Adults: Feasibility, Normal Physiology and Mechanisms in Healthy Volunteers
(Peer reviewed; Journal article, 2021)This study examines the feasibility of blood speckle tracking for vector flow imaging in healthy adults and describes the physiologic flow pattern and vortex formation in relation to the wall motion in the left ventricle. ... -
Intra‐arterial blood pressure traits during and after heavy resistance exercise in healthy males
(Journal article; Peer reviewed, 2019)This randomized within‐subjects crossover‐designed study evaluated intra‐arterial blood pressure (BP) traits in seven healthy males (24 ± 1 years) during heavy resistance exercise (HRE) to failure (10 × 5 repetitions, 5RES) ...