• norsk
    • English
  • English 
    • norsk
    • English
  • Login
View Item 
  •   Home
  • Øvrige samlinger
  • Publikasjoner fra CRIStin - NTNU
  • View Item
  •   Home
  • Øvrige samlinger
  • Publikasjoner fra CRIStin - NTNU
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Intravascular Targets for Molecular Contrast-Enhanced Ultrasound Imaging

Moestue, Siver Andreas; Gribbestad, Ingrid S; Hansen, Rune
Journal article, Peer reviewed
Thumbnail
View/Open
ijms-13-06679.pdf (1.712Mb)
URI
http://hdl.handle.net/11250/2356389
Date
2012
Metadata
Show full item record
Collections
  • Institutt for sirkulasjon og bildediagnostikk [1009]
  • Publikasjoner fra CRIStin - NTNU [19736]
Original version
International Journal of Molecular Sciences 2012, 13(6):6679-6697   10.3390/ijms13066679
Abstract
Molecular targeting of contrast agents for ultrasound imaging is emerging as a

new medical imaging modality. It combines advances in ultrasound technology with

principles of molecular imaging, thereby allowing non-invasive assessment of biological

processes in vivo. Preclinical studies have shown that microbubbles, which provide

contrast during ultrasound imaging, can be targeted to specific molecular markers. These

microbubbles accumulate in tissue with target (over) expression, thereby significantly

increasing the ultrasound signal. This concept offers safe and low-cost imaging with high

spatial resolution and sensitivity. It is therefore considered to have great potential in cancer

imaging, and early-phase clinical trials are ongoing. In this review, we summarize the

current literature on targets that have been successfully imaged in preclinical models using

molecularly targeted ultrasound contrast agents. Based on preclinical experience, we

discuss the potential clinical utility of targeted microbubbles.
Publisher
MDPI
Journal
International Journal of Molecular Sciences

Contact Us | Send Feedback

Privacy policy
DSpace software copyright © 2002-2019  DuraSpace

Service from  Unit
 

 

Browse

ArchiveCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsDocument TypesJournalsThis CollectionBy Issue DateAuthorsTitlesSubjectsDocument TypesJournals

My Account

Login

Statistics

View Usage Statistics

Contact Us | Send Feedback

Privacy policy
DSpace software copyright © 2002-2019  DuraSpace

Service from  Unit