The association between vascular factors and subjective memory impairment in older people : the HUNT study, Norway

Abstract

Objectives: Subjective memory impairment (SMI) is often considered an early sign of dementia. This study investigates the relationship between SMI and dementia-related vascular factors in older people. Method: This study was based on data from 12,255 individuals, 65 years and older, participating in the Nord-Trøndelag health study, third survey 2006-08 (HUNT3). SMI, vascular diseases, exercise, smoking, and alcohol consumption were self-reported. Blood pressure, cholesterol and body mass index (BMI) were clinically measured. SMI were predicted using linear regression analysis. Results: Stroke and heart disease were associated with SMI. High exercise intensity was associated with less SMI. Respondents with high systolic blood pressure (SBP) reported less SMI than those with moderate SBP. In men, low SBP was associated with significantly more SMI compared to those with moderate SBP. In women, moderate alcohol consumption compared to low alcohol consumption was associated with significantly more SMI. Conclusion: SMI was positively associated with stroke and heart disease in this study. For the other investigated vascular factors, we did not find strong relationships with SMI. However, for preventive and treatment purposes, it is noteworthy that high exercise intensity and high systolic blood pressure was associated with less SMI in both genders.