dc.contributor.author | Christensen, Eidi | |
dc.contributor.author | Mørk, Cato | |
dc.contributor.author | Foss, Olav Andreas | |
dc.date.accessioned | 2019-10-11T10:44:21Z | |
dc.date.available | 2019-10-11T10:44:21Z | |
dc.date.created | 2011-11-16T17:33:35Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Journal of Skin Cancer. 2011, . | nb_NO |
dc.identifier.issn | 2090-2905 | |
dc.identifier.uri | http://hdl.handle.net/11250/2621566 | |
dc.description.abstract | Topical photodynamic therapy (PDT) has limitations in the treatment of thick skin tumours. The aim of the study was to evaluate the effect of pre-PDT deep curettage on tumour thickness in thick (≥2 mm) basal cell carcinoma (BCC). Additionally, 3-month treatment outcome and change of tumour thickness from diagnosis to treatment were investigated. At diagnosis, mean tumour thickness was 2.3 mm (range 2.0–4.0). Pre- and post-curettage biopsies were taken from each tumour prior to PDT. Of 32 verified BCCs, tumour thickness was reduced by 50% after deep curettage . Mean tumour thickness was also reduced from diagnosis to treatment. At 3-month followup, complete tumour response was found in 93% and the cosmetic outcome was rated excellent or good in 100% of cases. In conclusion, deep curettage significantly reduces BCC thickness and may with topical PDT provide a favourable clinical and cosmetic short-term outcome. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Hindawi Publishing Corporation | nb_NO |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Pre-Treatment Deep Curettage Can Significantly Reduce Tumour Thickness in Thick Basal Cell Carcinoma While Maintaining a Favourable Cosmetic Outcome When Used in Combination with Topical Photodynamic Therapy | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.description.version | publishedVersion | nb_NO |
dc.source.pagenumber | 6 | nb_NO |
dc.source.journal | Journal of Skin Cancer | nb_NO |
dc.identifier.doi | 10.1155/2011/240340 | |
dc.identifier.cristin | 859066 | |
dc.description.localcode | © 2011 Eidi Christensen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | nb_NO |
cristin.unitcode | 194,65,15,0 | |
cristin.unitcode | 1920,9,0,0 | |
cristin.unitcode | 194,65,30,0 | |
cristin.unitname | Institutt for klinisk og molekylær medisin | |
cristin.unitname | Klinikk for ortopedi, revmatologi og hudsykdommer | |
cristin.unitname | Institutt for nevromedisin og bevegelsesvitenskap | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |