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Feature-based classification of human transcription factors into hypothetical sub-classes related to regulatory function.
(Peer reviewed; Journal article, 2016)Background Transcription factors are key proteins in the regulation of gene transcription. An important step in this process is the opening of chromatin in order to make genomic regions available for transcription. Data ... -
Femicide trends at the start of the 21st. century: Prevalence, risk factors and national public health actions
(Peer reviewed; Journal article, 2023)Lethal violence requires a gender-based analysis which recognises that femicide is different from homicide in many ways. Structural factors such as national income and wealth equality together with government policies may ... -
Femoral nailing associated with bone marrow emboli in pigs induced a specific increase in blood IL-6 and broad inflammatory responses in the heart and lungs
(Journal article; Peer reviewed, 2024)Introduction: Bone marrow embolization may complicate orthopedic surgery, potentially causing fat embolism syndrome. The inflammatory potential of bone marrow emboli is unclear. We aimed to investigate the inflammatory ... -
Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain
(Journal article; Peer reviewed, 2024)Background: Shaft fractures of the femur are commonly treated with intramedullary nailing, which can release bone marrow emboli into the bloodstream. Emboli can travel to the lungs, impairing gas exchange and causing ... -
Fetal head descent assessed by transabdominal ultrasound: a prospective observational study
(Peer reviewed; Journal article, 2021)Background Detection of copy number variation (CNV) in genes associated with disease is important in genetic diagnostics, and next generation sequencing (NGS) technology provides data that can be used for CNV detection. ... -
Fidelity of a motivational interviewing intervention for improving return to work for people with musculoskeletal disorders
(Peer reviewed; Journal article, 2021)The objective of this study was to conduct a fidelity evaluation of a motivational interviewing (MI) intervention delivered by social insurance caseworkers, in a three-arm randomized controlled trial (RCT) for improving ... -
Fidelity to an evidence-based model for crisis resolution teams: a cross-sectional multicentre study in Norway
(Peer reviewed; Journal article, 2021)Background Crisis resolution teams (CRTs) are specialized multidisciplinary teams intended to provide assessment and short-term outpatient or home treatment as an alternative to hospital admission for people experiencing ... -
The fight to keep resistance at bay, epidemiology of carbapenemase producing organisms (CPOs), vancomycin resistant enterococci (VRE) and methicillin resistant Staphylococcus aureus (MRSA) in Norway, 2006-2017
(Peer reviewed; Journal article, 2019)Introduction: Scandinavian countries have traditionally had a low prevalence of resistant organisms, but have in recent years experienced a change in their epidemiology. We aim to describe the epidemiology of carbapenema ... -
Fighting the waves; Covid-19 family life interference in a neurodevelopmental disorder-caregiver population
(Journal article; Peer reviewed, 2022) -
Filled prescriptions for opioids among children and adolescents – A nationwide study from 2010 to 2018
(Peer reviewed; Journal article, 2021)Background Prescribing opioids for children and adolescents should be reserved for advanced life-limiting diseases and moderate-to-severe acute pain. Pediatric codeine use is discouraged by several authorities, but the ... -
First-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial
(Journal article; Peer reviewed, 2024)Background We evaluated first-line treatment of metastatic microsatellite-stable colorectal cancer with short-course oxaliplatin-based chemotherapy alternating with immune checkpoint blockade. Methods Patients were ... -
Fitness center use and subsequent achievement of exercise goals. A prospective study on long-term fitness center members
(Peer reviewed; Journal article, 2022)Background Knowledge on the relationship between fitness center use and long-term members’ subsequent goal achievement is limited. Therefore, the aim was to investigate the prospective association between the use of fitness ... -
Five years of exercise intervention at different intensities and development of white matter hyperintensities in community dwelling older adults, a Generation 100 sub-study
(Peer reviewed; Journal article, 2022)We investigated if a five-year supervised exercise intervention with moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT) versus control; physical activity according to national guidelines, ... -
Five-year results of endovascular aortic repair used according to instructions for use give a good general outcome for abdominal aortic aneurysm
(Journal article; Peer reviewed, 2019)Objectives: The primary aim of this study was to investigate the rate of sac enlargement and secondary procedures after 5 years when instructions for use are strictly applied with endovascular aortic repair. The secondary ... -
Five-Year Risk of Cardiovascular Events after Transient Ischemic Attack: Results from a Prospective Cohort
(Journal article; Peer reviewed, 2024)Objectives. There are few contemporary, prospective studies reporting on the long-term risk of stroke and other cardiovascular (CV) events after transient ischemic attack (TIA). The primary aim was to examine the risk of ... -
FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells
(Journal article; Peer reviewed, 2023)Background: The immunophilin FKBP12 binds to TGF-β family type I receptors, including the BMP type I receptor ALK2. FKBP12 keeps the type I receptor in an inactive state and controls signaling activity. Removal of FKBP12 ... -
Flattening the quality of life curve? A prospective person-centred study from Norway amid COVID-19
(Peer reviewed; Journal article, 2022)Purpose We examined multidimensional, heterogeneous reactions to the COVID-19 pandemic and associated measures to provide further insights into the developmental processes of risk and adaptation. Method We used ... -
Fluctuations of sensorimotor processing in migraine: A controlled longitudinal study of beta event related desynchronization
(Journal article; Peer reviewed, 2019)Background The migraine brain seems to undergo cyclic fluctuations of sensory processing. For instance, during the preictal phase, migraineurs experience symptoms and signs of altered pain perception as well as other ... -
Flunarizine as prophylaxis for episodic migraine: a systematic review with meta-analysis
(Peer reviewed; Journal article, 2019)Based on few clinical trials, flunarizine is considered a first-line prophylactic treatment for migraine in several guidelines. In this meta-analysis, we examined the pooled evidence for its effectiveness, tolerability, ... -
Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis
(Peer reviewed; Journal article, 2023)Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ...