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Depression and antidepressant treatment in the development of hypertensive disorders of pregnancy: Results from a prospective cohort study
(Peer reviewed; Journal article, 2022)Background: Hypertensive disorders of pregnancy are associated with longer term cardiovascular risk. Understanding if depression or antidepressant use in pregnancy is associated with HDP is important in identifying those ... -
Depression and Personality Traits Across Adolescence—Within-Person Analyses of a Birth Cohort
(Journal article; Peer reviewed, 2024)Depressive symptoms and personality traits covary in adolescents, but our understanding of the nature of this relation is limited. Whereas a predisposition explanation posits that specific personality traits increase the ... -
Depression and Quality of Life in Older Persons: A Review
(Peer reviewed; Journal article, 2015)Background: Depression is a prevalent and disabling condition in older persons (≥60 years) that increases the risk of mortality and negatively influences quality of life (QOL). The relationship between depression, or ... -
Depression trajectories and cytokines in schizophrenia spectrum disorders - A longitudinal observational study
(Peer reviewed; Journal article, 2023)Depression occurs frequently in all phases of schizophrenia spectrum disorders. Altered activity in the immune system is seen in both depression and schizophrenia. We aimed to uncover depressive trajectories in a sample ... -
Depression, Anxiety, Insomnia, and Quality of Life in a Representative Community Sample of Older Adults Living at Home
(Peer reviewed; Journal article, 2022)Background: The aim of the study was to explore symptoms of anxiety and depression, insomnia, and quality of life in a Norwegian community sample of older adults. Methods: A representative sample (N = 1069) was drawn ... -
Descent of fetal head during active pushing: secondary analysis of prospective cohort study investigating ultrasound examination before operative vaginal delivery
(Peer reviewed; Journal article, 2019)Objectives To investigate if descent of the fetal head during active pushing is associated with duration of operative vaginal delivery, mode of delivery and neonatal outcome in nulliparous women with prolonged second stage ... -
Descent of the presenting part assessed with ultrasound
(Peer reviewed; Journal article, 2021)Fetal head descent can be expressed as fetal station and engagement. Station is traditionally based on clinical vaginal examination of the distal part of the fetal skull and related to the level of the ischial spines. ... -
Description of the prehospital emergency healthcare system in Norway
(Peer reviewed; Journal article, 2024)Background: Norway has a long coastline, steep mountains, and wide fjords, which presents some challenges to the prehospital emergency healthcare system. In recent years, the prehospital emergency medical services (EMS) ... -
Desflurane consumption with automated vapour control systems in two different anaesthesia machines. A randomized controlled study
(Peer reviewed; Journal article, 2021)Background: In general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied. Automated gas delivery devices are developed to reduce volatile anaesthetic consumption by limiting gas flow. This study ... -
Design, Development, and Evaluation of an mHealth App for Reporting of Side Effects During Cytostatic Treatment: Usability Test and Interview Study
(Peer reviewed; Journal article, 2023)Background: Using mobile health (mHealth) interventions such as smartphone apps to deliver health services is an opportunity to engage patients more actively in their own treatment. Usability tests allow for the evaluation ... -
Designing Serious Games for Cyber Ranges: A Socio-technical Approach
(Chapter, 2019)Appropriate training is an effective solution to tackle the evolving threat landscape and conflicts in the cyber domain and to fulfill security requirements. Serious games demonstrate pedagogic effectiveness in this field, ... -
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
(Peer reviewed; Journal article, 2022)Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease ... -
Detecting copy number variation in next generation sequencing data from diagnostic gene panels
(Peer reviewed; Journal article, 2021)Background Detection of copy number variation (CNV) in genes associated with disease is important in genetic diagnostics, and next generation sequencing (NGS) technology provides data that can be used for CNV detection. ... -
Detection of Cerebral High-Intensity Transient Signals by NeoDoppler during Cardiac Catheterization and Cardiac Surgery in Infants
(Peer reviewed; Journal article, 2022)There is a risk of gaseous and solid micro-embolus formation during transcatheter cardiac interventions and surgery in children with congenital heart disease (CHD). Our aim was to study the burden of high-intensity transient ... -
Detection of germline variants with pathogenic potential in 48 patients with familial colorectal cancer by using whole exome sequencing
(Peer reviewed; Journal article, 2023)Background Hereditary genetic mutations causing predisposition to colorectal cancer are accountable for approximately 30% of all colorectal cancer cases. However, only a small fraction of these are high penetrant mutations ... -
Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
(Peer reviewed; Journal article, 2021)Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ... -
Detection of recurrent prostate cancer with 18F-Fluciclovine PET/MRI
(Peer reviewed; Journal article, 2020)Objective: Simultaneous PET/MRI combines soft-tissue contrast of MRI with high molecular sensitivity of PET in one session. The aim of this prospective study was to evaluate detection rates of recurrent prostate cancer by ... -
Detection of subgenomic mRNA from endemic human coronavirus OC43 and NL63 compared to viral genomic loads, single virus detection and clinical manifestations in children with respiratory tract infections
(Peer reviewed; Journal article, 2022)Background The importance of endemic human coronavirus (HCoV) in children has been insufficiently elucidated upon. Our aims were to develop subgenomic (sg) mRNA tests for HCoV species OC43 and NL63, and to evaluate the ... -
Determinants for Effective ALECSAT Immunotherapy Treatment on Autologous Patient-Derived Glioblastoma Stem Cells
(Peer reviewed; Journal article, 2018)Glioblastoma (GBM) is the most aggressive primary brain tumor with a median survival of less than 15 months, emphasizing the need for better treatments. Immunotherapy as a treatment for improving or aiding the patient’s ... -
Determinants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: a cross-sectional sub-study of NoFRACT
(Peer reviewed; Journal article, 2019)Summary - Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, ...