• Lower Extremity Intermittent Negative Pressure for Intermittent Claudication. Follow-Up after 24 Weeks of Treatment 

      Hoel, Henrik; Pettersen, Erik Mulder; Høiseth, Lars Øivind; Mathiesen, Iacob; Seternes, Arne; Hisdal, Jonny (Peer reviewed; Journal article, 2021)
      Background Treatment with lower extremity intermittent negative pressure (INP) of -40 mm Hg for one hour twice daily for 12 weeks, increases walking capacity in patients with intermittent claudication (IC). However, the ...
    • Lower-Grade Gliomas: An Epidemiological Voxel-Based Analysis of Location and Proximity to Eloquent Regions 

      Gómez Vecchio, Tomás; Neimantaite, Alice; Corell, Alba; Bartek, Jiri; Jensdottir, Margret; Reinertsen, Ingerid; Solheim, Ole; Jakola, Asgeir S. (Peer reviewed; Journal article, 2021)
      Background: Glioma is the most common intra-axial tumor, and its location relative to critical areas of the brain is important for treatment decision-making. Studies often report tumor location based on anatomical taxonomy ...
    • Lower-Limb Lymphedema after Sentinel Lymph Node Biopsy in Cervical Cancer Patients 

      Cibula, David; Borcinova, Martina; Marnitz, Simone; Jarkovsky, Jiri; Klat, Jaroslav; Pilka, Radovan; Torne, Aureli; Zapardiel, Ignacio; Petiz, Almerinda; Lay, Laura; Sehnal, Borek; Ponce, Jordi; Felsinger, Michal; Arencibia-Sánchez, Octavio; Kascak, Peter; Zalewski, Kamil; Presl, Jiri; Palop-Moscardo, Alicia; Tingulstad, Solveig Kristi; Vergote, Ignace; Redecha, Mikulas; Fruhauf, Filip; Kohler, Christhardt; Kocian, Roman (Peer reviewed; Journal article, 2021)
      Background: To prospectively assess LLL incidence among cervical cancer patients treated by uterine surgery complemented by SLN biopsy, without PLND. Methods: A prospective study in 150 patients with stage IA1–IB2 cervical ...
    • Lung cancer biomarker testing: perspective from Europe 

      Thunnissen, Erik; Weynand, Birgit; Udovicic-Gagula, Dalma; Brcic, Luka; Szolkowska5, Malgorzata; Hofman, Paul; Smojver-Ježek, Silvana; Anttila, Sisko; Calabrese, Fiorella; Kern, Isidor; Skov, Birgit; Perner, Sven; Dale, Vibeke Grotnes; Eri, Zivka; Haragan, Alex; Leonte, Diana; Carvallo, Lina; Prince, Spasenja Savic; Nicholson, Siobhan; Sansano, Irene; Ryska, Ales (Peer reviewed; Journal article, 2020)
      A questionnaire on biomarker testing previously used in central European countries was extended and distributed in Western and Central European countries to the pathologists participating at the Pulmonary Pathology Society ...
    • Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema 

      Rasch-Halvorsen, Øystein; Steinshamn, Sigurd Loe; Langhammer, Arnulf; Hassel, Erlend; Brumpton, Ben Michael; Jenssen, Haldor; Spruit, Martijn A. (Journal article; Peer reviewed, 2021)
      Previous studies of associations of forced expiratory lung volume in one second (FEV1) with peak oxygen uptake (VO2peak) in chronic obstructive pulmonary disease (COPD) have not taken sex, age and height related variance ...
    • Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations 

      Sjursen, Wenche; McPhillips, Mary; Scott, Rodney J.; Talseth-Palmer, Bente (Peer reviewed; Journal article, 2016)
      Background Lynch syndrome, the most frequent hereditary colorectal cancer syndrome, is caused by defects in mismatch repair genes. Genetic testing is important in order to identify mutation carriers who can benefit from ...
    • M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis 

      Brix, Ninna; Glerup, Mia; Thiel, Steffen; Mistegaard, Clara Elbæk; Skals, Regitze Gyldenholm; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan Mary; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels (Peer reviewed; Journal article, 2021)
      Objective: Distinction on clinical grounds between acute lymphoblastic leukaemia presenting with arthropathy (ALLarthropathy) and juvenile idiopathic arthritis (JIA) is difficult, as the clinical and paraclinical signs of ...
    • Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury 

      Gravesteijn, BY; Nieboer, Daan; Ercole, Ari; Lingsma, Hester F; Nelson, David; Van Calster, Ben; Steyerberg, Ewout W; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Objective We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study Design and Setting We performed logistic regression ...
    • Machine learning augmented reduced-order models for FFR-prediction 

      Fossan, Fredrik Eikeland; Müller, Lucas O.; Sturdy, Jacob; Bråten, Anders Tjellaug; Jørgensen, Arve; Wiseth, Rune; Hellevik, Leif Rune (Peer reviewed; Journal article, 2021)
      Computational predictions in cardiovascular medicine have largely relied on explicit models derived from physical and physiological principles. Recently, the application of artificial intelligence in cardiovascular medicine ...
    • Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial 

      Rakaee, Mehrdad; Andersen, S.; Giannikou, K.; Paulsen, Erna-Elise; Kilvær, Thomas Karsten; Rasmussen Busund, Lill-Tove; Berg, Thomas; Richardsen, Elin; Lombardi, Ana Paola; Adib, E.; Pedersen, Mona Irene; Tafavvoghi, Masoud; Wahl, Sissel Gyrid Freim; Petersen, R.H.; Bondgaard, A.L.; Yde, C.W.; Baudet, C.; Licht, P.; Lund-Iversen, Marius; Grønberg, Bjørn Henning; Fjellbirkeland, Lars; Helland, Åslaug; Pøhl, M.; Kwiatkowski, D.J.; Dønnem, Tom (Peer reviewed; Journal article, 2023)
      Background We aim to implement an immune cell score model in routine clinical practice for resected non-small-cell lung cancer (NSCLC) patients (NCT03299478 ). Molecular and genomic features associated with immune ...
    • Machine prescription for chronic migraine 

      Stubberud, Anker; Gray, Robert; Tronvik, Erling Andreas; Matharu, Manjit Singh; Nachev, Parashkev (Peer reviewed; Journal article, 2022)
      Responsive to treatment individually, chronic migraine remains strikingly resistant collectively, incurring the second-highest population burden of disability worldwide. A heterogeneity of responsiveness, requiring ...
    • Macroscopic appearance of the major duodenal papilla influences bile duct cannulation: a prospective multicenter study by the Scandinavian Association for Digestive Endoscopy Study Group for ERCP 

      Haraldsson, Erik; Kylanpää, Leena; Grönroos, Juha; Saarela, Arto; Toth, Ervin; Qvigstad, Gunnar; Hult, Mari; Lindström, Outi; Laine, Simo; Karjula, Heikki; Hauge, Truls; Sadik, Riadh; Arnelo, Urban (Journal article, 2019)
      Background and Aims: Certain appearances of the major duodenal papilla have been claimed to make cannulation more difficult during ERCP. This study uses a validated classification of the endoscopic appearance of the major ...
    • Magnetic Lenz lenses improve the limit-of-detection in nuclear magnetic resonance 

      Spengler, Nils; While, Peter Thomas; Meissner, Markus V; Wallrabe, Ulrike; Korvink, Jan G. (Peer reviewed; Journal article, 2017)
      A high NMR detection sensitivity is indispensable when dealing with mass and volume-limited samples, or whenever a high spatial resolution is required. The use of miniaturised RF coils is a proven way to increase sensitivity, ...
    • Magnetic resonance-based eye tracking using deep neural networks 

      Frey, Markus; Nau, Matthias; Doeller, Christian F. (Journal article, 2021)
      Viewing behavior provides a window into many central aspects of human cognition and health, and it is an important variable of interest or confound in many functional magnetic resonance imaging (fMRI) studies. To make eye ...
    • Making Neglect Invisible: A Qualitative Study among Nursing Home Staff in Norway 

      Lund, Stine Borgen; Skolbekken, John-Arne; Mosqueda, Laura; Malmedal, Wenche Karin (Peer reviewed; Journal article, 2023)
      Background: Research shows that nursing home residents’ basic care needs are often neglected, potentially resulting in incidents that threaten patients’ safety and quality of care. Nursing staff are at the frontline for ...
    • The Mammalian Cap-Specific m<sup>6</sup>Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues 

      Pandey, Radha Raman; Delfino, Elena; Homolka, David; Roithova, Adriana; Chen, Kuan-Ming; Li, Lingyun; Franco, Giulia; Vågbø, Cathrine Broberg; Taillebourg, Emmanuel; Fauvarque, Marie-Odile; Pillai, Ramesh S. (Peer reviewed; Journal article, 2020)
      The 5′ end of eukaryotic mRNAs is protected by the m7G-cap structure. The transcription start site nucleotide is ribose methylated (Nm) in many eukaryotes, whereas an adenosine at this position is further methylated at the ...
    • The management and clinical knowledge of headache disorders among general practitioners in Norway: a questionnaire survey 

      Kristoffersen, Espen Saxhaug; Faiz, Kashif Waqar; Hansen, Jakob Møller; Tronvik, Erling Andreas; Frich, Jan C; Lundqvist, Christofer; Winsvold, Bendik K S (Peer reviewed; Journal article, 2021)
      Background General practitioners (GPs) diagnose and manage a majority of headache patients seeking health care. With the aim to understand the potential for clinical improvement and educational needs, we performed a study ...
    • Management of arterial partial pressure of carbon dioxide in the frst week after traumatic brain injury: results from the CENTER-TBI study 

      Citerio, Giuseppe; Robba, Chiara; Rebora, Paola; Petrosino, Matteo; Rossi, elenora; Malgeri, L; Stocchetti, Nino; Galimberti, Stefania; Menon, David K.; Andelic, Nada; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brinck, Vibeke; Brazinova, Alexandra; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria rosa; Cameron, Peter; Lozano, Guillermo carbayo; Chevallard, Giorgio; Carbonara, Marco; Chieregato, Arturo; Citerio, Giuseppe; Cnossen, Maryse; Coburn, Mark (Peer reviewed; Journal article, 2021)
      Purpose To describe the management of arterial partial pressure of carbon dioxide (PaCO2) in severe traumatic brain-injured (TBI) patients, and the optimal target of PaCO2 in patients with high intracranial pressure ...
    • Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding 

      Bjørk, Marte-Helene; Kristoffersen, Espen Saxhaug; Tronvik, Erling Andreas; Nordeng, Hedvig Marie Egeland (Peer reviewed; Journal article, 2021)
      Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting ...
    • Management of COVID-19 in a Deployed Setting 

      Medby, Christian; Clifford, Sandra Larssen; Norquay, Miranda; Hansen, Therese Killi; Gurney, Jennifer (Peer reviewed; Journal article, 2021)
      Introduction: Hamid Karzai International Airport is a NATO military base connected to the international airport in Kabul, Afghanistan. It is one of the larger NATO installations in Afghanistan, and with its location being ...