Blar i St. Olavs hospital på tittel

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    • FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells 

      Quist-Løkken, Ingrid; Andersson-Rusch, Clara Leticia; Kastnes, Martin Haugrud; Jürgen Markus Kolos, , Jürgen Markus; Jatzlau, Jerome; Hella, Hanne; Olsen, Oddrun Elise; Sundan, Anders; Knaus, Petra; Hausch, Felix; Holien, Toril (Journal article; Peer reviewed, 2023)
      Background: The immunophilin FKBP12 binds to TGF-β family type I receptors, including the BMP type I receptor ALK2. FKBP12 keeps the type I receptor in an inactive state and controls signaling activity. Removal of FKBP12 ...

    • Flattening the quality of life curve? A prospective person-centred study from Norway amid COVID-19 

      Nes, Ragnhild Bang; Yu, Baeksan; Hansen, Thomas; Vedaa, Øystein; Røysamb, Espen; Nilsen, Thomas Sevenius (Peer reviewed; Journal article, 2022)
      Purpose We examined multidimensional, heterogeneous reactions to the COVID-19 pandemic and associated measures to provide further insights into the developmental processes of risk and adaptation. Method We used ...

    • Fluctuations of sensorimotor processing in migraine: A controlled longitudinal study of beta event related desynchronization 

      Mykland, Martin Syvertsen; Bjørk, Marte-Helene; Stjern, Marit; Omland, Petter Moe; Uglem, Martin; Sand, Trond (Journal article; Peer reviewed, 2019)
      Background The migraine brain seems to undergo cyclic fluctuations of sensory processing. For instance, during the preictal phase, migraineurs experience symptoms and signs of altered pain perception as well as other ...

    • Flunarizine as prophylaxis for episodic migraine: a systematic review with meta-analysis 

      Stubberud, Anker; Flaaen, Nikolas Melseth; McCrory, Douglas C.; Pedersen, Sindre Andre; Linde, Mattias (Peer reviewed; Journal article, 2019)
      Based on few clinical trials, flunarizine is considered a first-line prophylactic treatment for migraine in several guidelines. In this meta-analysis, we examined the pooled evidence for its effectiveness, tolerability, ...

    • Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis 

      Niemsiri, Vipavee; Rosenthal, Sara Brin; Nievergelt, Caroline M.; Maihofer, Adam X.; Marchetto, Maria C.; Santos, Renata; Shekhtman, Tatyana; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William H.; DeModena, Anna; Eyler, Lisa T.; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark A.; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; McCarthy, Michael J.; McInnis, Melvin G.; Craig, David; Millett, Caitlin E.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Donovan, Claire O’; Ødegaard, Ketil Joachim; Ryan, Kelly; Schinagle, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma K.; Stautland, Andrea; Tarwater, Bruce; Zandi, Peter P.; Alda, Martin; Fisch, Kathleen M.; Gage, Fred H.; Kelsoe, John R. (Peer reviewed; Journal article, 2023)
      Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ...

    • FollowTheSutures: Piloting a new way to administer onabotulinumtoxinA for chronic migraine. 

      Stovner, Lars Jacob; Hagen, Knut; Tronvik, Erling Andreas; Gravdahl, Gøril Bruvik; Burstein, Rami; Dodick, David W. (Peer reviewed; Journal article, 2022)
      Background Anatomical and experimental data indicate that onabotulinimtoxin A could be more efficient and cost-effective for treating chronic migraine with injections targeting the cranial sutures, where collaterals from ...

    • Food intake by Patient-Generated Subjective Global Assessment (PG-SGA) corresponds to energy and protein intake as well as weight change in patients with advanced cancer 

      Bye, Asta; Meli, Kari; Solheim, Tora Skeidsvoll; Laird, Barry J; Kaasa, Stein; Stene, Guro Birgitte; Balstad, Trude Rakel (Journal article; Peer reviewed, 2019)
      Background & aims The aim of this study was to test how well the Patient-Generated Subjective Global Assessment (PG-SGA) question about food intake correlates with a well-established measurement of food intake. Furthermore, ...

    • Forebyggende gruppetrening for hjemmeboende eldre : hvem deltar og hva gir motivasjon til å delta? 

      Granbo, Randi; Taraldsen, Kristin; Thingstad, Pernille; Solberg, Hilde Strøm; Simonsen, Elin; Helbostad, Jorunn L. (Peer reviewed; Journal article, 2015)
      Bakgrunn: I årene framover vil andelen eldre i befolkningen øke. Kommunene ut¬fordres til å utvikle tjenester i et mer forebyggende perspektiv. Forebyggende grup¬petrening har eksistert i Trondheim siden 2006, og benyttes ...

    • Forecasting migraine with machine learning based on mobile phone diary and wearable data 

      Stubberud, Anker; Ingvaldsen, Sigrid Hegna; Brenner, Eiliv; Winnberg, Ingunn Grøntveit; Olsen, Alexander; Gravdahl, Gøril Bruvik; Matharu, Manjit Singh; Nachev, Parashkev; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2023)
      Introduction Triggers, premonitory symptoms and physiological changes occur in the preictal migraine phase and may be used in models for forecasting attacks. Machine learning is a promising option for such predictive ...

    • Forskjeller i mortalitet hos traumepasienter 

      Wisborg, Torben; Dehli, Trond; Eken, Torsten; Brattebø, Guttorm; Johnsen, Lars Gunnar (Peer reviewed; Journal article, 2023)
      Mortaliteten blant norske traumepasienter i perioden 2015–18 var på linje med de beste resultatene fra andre land, men fortsatt fant vi regionale forskjeller og forskjeller mellom sykehusnivåer. Selv om resultatene er bra, ...

    • Fragmentation assessment of FFPE DNA helps in evaluating NGS library complexity and interpretation of NGS results 

      Ottestad, Anine Larsen; Emdal, Elisabeth Fritzke; Grønberg, Bjørn Henning; Halvorsen, Tarje Onsøien; Dai, Hong Yan (Journal article; Peer reviewed, 2022)

    • Frailty and survival in elderly intensive care patients in Norway 

      Andersen, Finn Husøy; Haaland, Øystein Ariansen; Klepstad, Pål; Flaatten, Hans (Journal article; Peer reviewed, 2021)
      Background Today, 10%-15% of Norwegian intensive care patients are ≥80 years. This proportion will increase significantly over the next 20 years, but it is unlikely that resources for intensive care increase correspondingly. ...

    • Frailty identified by geriatric assessment is associated with poor functioning, high symptom burden and increased risk of physical decline in older cancer patients: Prospective observational study 

      Kirkhus, Lene; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Hjermstad, Marianne Jensen; Rostoft, Siri; Harneshaug, Magnus; Selbæk, Geir; Wyller, Torgeir Bruun; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)
      Background: Maintaining quality of life including physical functioning is highly prioritized among older cancer patients. Geriatric assessment is a recommended approach to identify patients with increased vulnerability ...

    • Frequency and predictors of headache in the first 12 months after traumatic brain injury: results from CENTER-TBI 

      Howe, Emilie Isager; Andelic, Nada; Brunborg, Cathrine; Zeldovich, Marina; Helseth, Eirik; Skandsen, Toril; Olsen, Alexander; Fure, Silje Christine Reistad; Theadom, Alice; Rauen, Katrin; Madsen, Benedikte Årebrot; Jacobs, Bram; van der Naalt, Joukje; Tartaglia, Maria Carmela; Einarsen, Cathrine Elisabeth; Storvig, Gøril; Tronvik, Erling Andreas; Tverdal, Cathrine Buaas; von Steinbüchel, Nicole; Røe, Cecilie; Hellstrøm, Torgeir (Journal article; Peer reviewed, 2024)
      Background: Headache is a prevalent and debilitating symptom following traumatic brain injury (TBI). Large-scale, prospective cohort studies are needed to establish long-term headache prevalence and associated factors after ...

    • Frequency of Boiled Potato Consumption and All-Cause and Cardiovascular Disease Mortality in the Prospective Population-Based HUNT Study 

      Moholdt, Trine; Nilsen, Tom I. L. (Peer reviewed; Journal article, 2021)
      Few studies have assessed the association between potato consumption and mortality, especially cardiovascular disease (CVD) mortality. Our objective was to investigate the association between consumption of boiled potatoes ...

    • Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study 

      Andelic, Nada; Røe, Cecilie; Brunborg, Cathrine; Zeldovich, Marina; Løvstad, Marianne; Løke, Daniel; Borgen, Ida Maria Henriksen; Voormolen, Daphne; Howe, Emilie; Forslund, Marit Vindal; DAHL, HILDE MARGRETE; von Steinbuechel, Nicole; Helseth, Eirik; Røise, Olav; Frisvold, Shirin; Anke, Audny; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Background Fatigue is one of the most commonly reported subjective symptoms following traumatic brain injury (TBI). The aims were to assess frequency of fatigue over the first 6 months after TBI, and examine whether fatigue ...

    • The frequency of intrapartum caesarean section use with the WHO partograph versus Zhang's guideline in the Labour Progression Study (LaPS): a multicentre, cluster-randomised controlled trial 

      Bernitz, Stine; Dalbye, Inger Sofie Rebecka; Zhang, Jun; Eggebø, Torbjørn Moe; Frøslie, Kathrine Frey; Olsen, Inge Christoffer; Blix, Ellen; Øian, Pål (Peer reviewed; Journal article, 2018)
      Background There is an ongoing debate concerning which guidelines and monitoring tools are most beneficial for assessing labour progression, to help prevent use of intrapartum caesarean section (ICS). The WHO partograph ...

    • Frontoamygdala hyperconnectivity predicts affective dysregulation in adolescent moderate-severe TBI 

      Bickart, Kevin C.; Olsen, Alexander; Dennis, Emily L.; Babikian, Talin; Hoffman, Ann N.; Snyder, Aliyah; Sheridan, Christopher A.; Fischer, Jesse T.; Giza, Christopher C.; Choe, Meeryo C.; Asarnow, Robert F. (Peer reviewed; Journal article, 2022)
      In survivors of moderate to severe traumatic brain injury (msTBI), affective disruptions often remain underdetected and undertreated, in part due to poor understanding of the underlying neural mechanisms. We hypothesized ...

    • Fully digital self-screening for atrial fibrillation with patch electrocardiogram 

      Sandberg, Edvard Liljedahl; Halvorsen, Sigrun; Berge, Trygve; Grimsmo, Jostein; Atar, Dan; Fensli, Rune Werner; Grenne, Bjørnar Leangen; Jortveit, Jarle (Peer reviewed; Journal article, 2023)
      Aims Atrial fibrillation (AF) is the most common arrhythmia worldwide. The AF is associated with severe mortality, morbidity, and healthcare costs, and guidelines recommend screening people at risk. However, screening ...

    • Fully Integrated Oncology and Palliative Care Services at a Local Hospital in Mid-Norway: Development and Operation of an Innovative Care Delivery Model 

      Brenne, Anne-Tove; Knudsen, Anne Kari; Raj, Sunil Xavier; Skjelvan, Laila Strand; Lund, Jo-Åsmund; Thronæs, Morten; Løhre, Erik Torbjørn; Hågensen, Liv Ågot; Brunelli, Cinzia; Kaasa, Stein (Peer reviewed; Journal article, 2020)
      Introduction Early access to cancer palliative care is recommended. Descriptions of structures and processes of outpatient palliative care clinics operated within smaller hospitals are scarce. This paper presents the ...