Now showing items 770-789 of 2469

    • European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation 

      Budu-Aggrey, Ashley; Kilanowski, Anna; Sobczyk, Maria K.; Shringarpure, Suyash S.; Mitchell, Ruth; Reis, Kadri; Reigo, Anu; Mägi, Reedik; Nelis, Mari; Tanaka, Nao; Brumpton, Ben Michael; Thomas, Laurent Francois; Sole-Navais, Pol; Flatley, Christopher; Espuela-Ortiz, Antonio; Herrera-Luis, Esther; Lominchar, Jesus V. T.; Bork-Jensen, Jette; Marenholz, Ingo; Arnau-Soler, Aleix; Jeong, Ayoung; Fawcett, Katherine A.; Baurecht, Hansjorg; Rodriguez, Elke; Alves, Alexessander Couto; Kumar, Ashish; Sleiman, Patrick M.; Chang, Xiao; Medina-Gomez, Carolina; Hu, Chen; Xu, Cheng-jian; Qi, Cancan; El-Heis, Sarah; Titcombe, Philip; Antoun, Elie; Fadista, João; Wang, Carol A.; Thiering, Elisabeth; Wu, Baojun; Kress, Sara; Kothalawala, Dilini M.; Kadalayil, Latha; Duan, Jiasong; Zhang, Hongmei; Hadebe, Sabelo; Hoffmann, Thomas; Jorgenson, Eric; Choquet, Hélène; Risch, Neil; Njølstad, Pål Rasmus; Andreassen, Ole; Johansson, Stefan; Almqvist, Catarina; Gong, Tong; Ullemar, Vilhelmina; Karlsson, Robert; Magnusson, Patrik K. E.; Szwajda, Agnieszka; Burchard, Esteban G.; Thyssen, Jacob P.; Hansen, Torben; Kårhus, Line L.; Dantoft, Thomas M.; Jeanrenaud, Alexander C.S.N.; Ghauri, Ahla; Arnold, Andreas; Homuth, Georg; Lau, Susanne; Nöthen, Markus M.; Hübner, Norbert; Imboden, Medea; Visconti, Alessia; Falchi, Mario; Bataille, Veronique; Hysi, Pirro; Ballardini, Natalia; Boomsma, Dorret I.; Hottenga, Jouke J.; Müller-Nurasyid, Martina; Ahluwalia, Tarunveer S.; Stokholm, Jakob; Chawes, Bo; Schoos, Ann-Marie M.; Esplugues, Ana; Bustamante, Mariona; Raby, Benjamin; Arshad, Syed; German, Chris; Esko, Tõnu; Milani, Lili A.; Metspalu, Andres; Terao, Chikashi; Abuabara, Katrina; Løset, Mari; Hveem, Kristian; Jacobsson, Bo; Pino-Yanes, Maria; Strachan, David P.; Grarup, Niels; Linneberg, Allan; Lee, Young-Ae; Probst-Hensch, Nicole; Weidinger, Stephan; Jarvelin, Marjo-Riitta; Melén, Erik; Hakonarson, Hakon; Irvine, Alan D.; Jarvis, Deborah; Nijsten, Tamar; Duijts, Liesbeth; Vonk, Judith M.; Koppelmann, Gerard H.; Godfrey, Keith M.; Barton, Sheila J.; Feenstra, Bjarke; Pennell, Craig E.; Sly, Peter D.; Holt, Patrick G.; Williams, L. Keoki; Bisgaard, Hans; Bønnelykke, Klaus; Curtin, John; Simpson, Angela; Murray, Clare; Schikowski, Tamara; Bunyavanich, Supinda; Weiss, Scott T.; Holloway, John W.; Min, Josine L.; Brown, Sara J.; Standl, Marie; Paternoster, Lavinia (Peer reviewed; Journal article, 2023)
      Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery ...
    • European guidelines on microscopic colitis: United European Gastroenterology (UEG) and European Microscopic Colitis Group (EMCG) statements and recommendations 

      Miehlke, Stephan; Guagnozzi, Danila; Zabana, Yamile; Tontini, Gian E; Fiehn, Anne-Marie Kanstrup; Wildt, Signe; Bohr, Johan; Bonderup, Ole K.; Bouma, Gerd; D’Amato, Mauro; Engel, Peter Johan Heiberg; Fernandez-Banares, Fernando; Macaigne, Gilles; Hjortswang, Henrik; Hultgren-Hörnquist, Elisabeth; Koulaouzidis, Anastasios; Kupcinskas, Jouzas; Landolfi, Stefania; Latella, Giovanni; Lucendo, Alfredo; Lyutakov, Ivan; Madisch, Ahmed; Magro, Fernando; Marlicz, Wojciech; Mihaly, Emese; Munck, Lars Kristian; Østvik, Ann Elisabet; Patai, Árpád V; Penchev, Plamen; Skonieczna-Żydecka, Karolina; Verhaegh, Bas; Münch, Andreas (Peer reviewed; Journal article, 2020)
      Introduction Microscopic colitis is a chronic inflammatory bowel disease characterised by normal or almost normal endoscopic appearance of the colon, chronic watery, nonbloody diarrhoea and distinct histological abnormalities, ...
    • Evaluating Evidence-Based Content, Features of Exercise Instruction, and Expert Involvement in Physical Activity Apps for Pregnant Women: Systematic Search and Content Analysis 

      Hayman, Melanie J; Alfrey, Kristie-Lee; Waters, Kim; Cannon, Summer; Mielke, Gregore I; Keating, Shelley E; Mena, Gabriela P; Mottola, Michelle F; Evenson, Kelly R; Davenport, Margie H; Barlow, S Ariel; Budzynski-Seymour, Emily; Comardelle, Natalie; Dickey, Madison; Harrison, Cheryce L; Kebbe, Maryam; Moholdt, Trine; Moran, Lisa J; Nagpal, Taniya S; Schoeppe, Stephanie; Alley, Stephanie; Brown, Wendy J; Williams, Susan; Vincze, Lisa (Peer reviewed; Journal article, 2022)
      Background: Guidelines for physical activity and exercise during pregnancy recommend that all women without contraindications engage in regular physical activity to improve both their own health and the health of their ...
    • Evaluating the Impact of High Intensity Interval Training on Axial Psoriatic Arthritis Based on MR Images 

      Chronaiou, Ioanna; Giskeødegård, Guro F.; Neubert, Ales; Hoffmann-Skjøstad, Tamara Viola; Thomsen, Ruth Stoklund; Hoff, Mari; Bathen, Tone Frost; Sitter, Beathe (Journal article; Peer reviewed, 2022)
      High intensity interval training (HIIT) has been shown to benefit patients with psoriatic arthritis (PsA). However, magnetic resonance (MR) imaging has uncovered bone marrow edema (BME) in healthy volunteers after vigorous ...
    • Evaluation of a surgical task sharing training programme's logbook system in Sierra Leone 

      Svendsen, Øyvind Veel; Helgerud, C; van Duinen, Aalke Johan; Salvesen, Øyvind; George, Peter M.; Bolkan, Håkon Angell (Journal article; Peer reviewed, 2019)
      Background Personal logbooks are universally applied for monitoring and evaluation of surgical trainees; however, the quality and accuracy of such logbooks in low income countries (LICs) are poorly examined. Logbooks ...
    • The evaluation of aortic stenosis, how the new guidelines are implemented across Europe: A survey by EACVI 

      Michalski, Blazej; Dweck, Mark R.; Marsan, Nina Ajmone; Cameli, Matteo; D'Andrea, Antonello; Carvalho, Ricardo Fontes; Holte, Espen; Podlesnikar, Tomaz; Manka, Robert; Haugaa, Kristina (Peer reviewed; Journal article, 2020)
      Aortic stenosis (AS) is the most prevalent valvular disease in developed countries, with a prevalence that is set to expand further with an ageing population. The most recent guidelines on valvular heart disease published ...
    • Evaluation of medical and surgical treatments for hidradenitis suppurativa using real-life data from the Scandinavian registry (HISREG) 

      Grimstad, Øystein; Tzellos, Thrasyvoulos; Dufour, Deirdre Nathalie; Bremnes, Øyvind Magne; Skoie, Inger Marie; Snekvik, Ingrid; Jarnæss, Elisabeth; Kyrgidis, Anathassios; Ingvarsson, Gisli (Peer reviewed; Journal article, 2019)
      Background: Hidradenitis suppurativa (HS) substantially affects health-related quality-of-life outcomes. Most treatment options are supported by low quality of evidence without validated outcomes. Objective: The aim of ...
    • Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial 

      Barratt-Due, Andreas; Olsen, Inge Christoffer; Nezvalova-Henriksen, Katerina; Kåsine, Trine; Lund-Johansen, Fridtjof; Hoel, Hedda Benedicte; Holten, Aleksander Rygh; Tveita, Anders Aune; Mathiessen, Alexander; Haugli, Mette; Eiken, Ragnhild; Kildal, Anders Benjamin; Berg, Åse; Johannessen, Asgeir; Heggelund, Lars; Dahl, Tuva Børresdatter; Skåra, Karoline Hansen; Pawel, Mielnik; Le, Lan Ai Kieu; Thoresen, Lars; Ernst, Gernot; Hoff, Dag Arne Lihaug; Skudal, Hilde Kristin; Kittang, Bård Reiakvam; Olsen, Roy Bjørkholt; Tholin, Birgitte; Ystrøm, Carl Magnus; Skei, Nina Vibeche; Tran, Trung; Dudman, Susanne Gjeruldsen; Andersen, Jan Terje; Hannula, Raisa; Dalgard, Olav; Finbråten, Ane-Kristine; Tonby, Kristian; Blomberg, Bjørn; Aballi, Saad; Fladeby, Cathrine; Steffensen, Anne Katrine; Müller, Fredrik; Dyrhol-Riise, Anne Ma; Trøseid, Marius; Aukrust, Pål (Peer reviewed; Journal article, 2021)
      Background: New treatment modalities are urgently needed for patients with COVID-19. The World Health Organization (WHO) Solidarity trial showed no effect of remdesivir or hydroxychloroquine (HCQ) on mortality, but the ...
    • Evaluation of the EQ-5D-3L and 5L versions in low back pain patients 

      Garratt, Andrew; Furunes, Håvard; Hellum, Christian; Solberg, Tore; Brox, Jens Ivar; Storheim, Kjersti; Johnsen, Lars Gunnar (Peer reviewed; Journal article, 2021)
      Background The EuroQol EQ-5D is one of the most widely researched and applied patient-reported outcome measures worldwide. The original EQ-5D-3L and more recent EQ-5D-5L include three and five response categories respectively. ...
    • Evaluation of the proliferation markers Ki-67/MIB-1, mitosin, survivin, pHH3, and DNA topoisomerase II alpha in human anaplastic astrocytomas - an immunohistochemical study 

      Habberstad, Andreas Hanssønn; Gulati, Sasha; Torp, Sverre Helge (Journal article; Peer reviewed, 2011)
      Background Histological malignancy grading of astrocytomas can be challenging despite criteria given by the World Health Organisation (WHO). Grading is fundamental for optimal prognostication and treatment, and additional ...
    • Evaluation of treatment with two weeks of doxycycline on macrolide-resistant strains of Mycoplasma genitalium: a retrospective observational study 

      Gossé, Marianne; Nordbø, Svein Arne; Pukstad, Brita (Peer reviewed; Journal article, 2021)
      Background Increasing macrolide resistance makes treatment of Mycoplasma genitalium infections challenging. The second-line treatment is moxifloxacin, an antibiotic drug best avoided due to the potential of severe side ...
    • Evaluering av konsekvensene av lovendring om særreaksjoner og varetektssurrogat 

      Holst, Øyvind; Mindestrømmen, Martin; Flåan, Oksana; Rypdal, Knut (Research report, 2021)
      Denne rapporten oppsummerer en evaluering av konsekvensene av lovendringer om tidsbestemt særreaksjon og varetektssurrogat. Terskelen for å ta ut tiltale for en tidsbestemt særreaksjon ser ut til å ligge høyt. Dette ser ...
    • Even low level of physical activity is associated with reduced mortality among people with metabolic syndrome, a population based study (the HUNT 2 study, Norway) 

      Stensvold, Dorthe; Nauman, Javaid; Nilsen, Tom Ivar Lund; Wisløff, Ulrik; Slørdahl, Stig Arild; Vatten, Lars Johan (Journal article; Peer reviewed, 2011)
      Background Low levels of physical activity may increase the risk of developing metabolic syndrome, a cluster of metabolic factors that are associated with the risk of premature death. It has been suggested that physical ...
    • Evening light environments can be designed to consolidate and increase the duration of REM-sleep 

      Vethe, Daniel; Drews, Henning Johannes; Scott, Janine Linda; Engstrøm, Morten; Heglum, Hanne Siri Amdahl; Grønli, Janne; Wisor, J.P.; Sand, Trond; Lydersen, Stian; Kjørstad, Kaia; Faaland, Patrick; Vestergaard, Cecilie Lund; Langsrud, Knut; Kallestad, Håvard (Peer reviewed; Journal article, 2022)
      Evening exposure to short-wavelength light has disruptive effects on circadian rhythms and sleep. These effects can be mitigated by blocking short-wavelength (blue) frequencies, which has led to the development of evening ...
    • Evidence of impaired bone quality in men with type 1 diabetes: A cross-sectional study 

      Syversen, Unni; Mosti, Mats Peder; Mynarek, Ida Maria; Vedal, Trude Seselie Jahr; Aasarød, Kristin Matre; Basso, Trude; Reseland, Janne E.; Thorsby, Per Medbøe; Asvold, Bjorn O.; Eriksen, Erik Fink; Stunes, Astrid Kamilla (Peer reviewed; Journal article, 2021)
      Objective Type 1 diabetes (T1D) is associated with substantial fracture risk. Bone mineral density (BMD) is, however, only modestly reduced, suggesting impaired bone microarchitecture and/or bone material properties. Yet, ...
    • Evolution and risk factors of anal incontinence during the first 6 years after first delivery: a prospective cohort study 

      Johannessen, Hege Hølmo; Mørkved, Siv; Stordahl, Arvid; Wibe, Arne; Falk, Ragnhild Sørum (Journal article; Peer reviewed, 2020)
    • Examination of the knowledge gap of return-to-work outcomes in routine outpatient treatment for common mental disorders: a systematic review 

      Lundqvist, Jakob Samuel; Brattmyr, Lars Martin; Lindberg, Martin Schevik; Havnen, Audun; Solem, Stian; Hjemdal, Odin (Peer reviewed; Journal article, 2023)
      Objective: Little is known about the effects of routine mental health care on return-to-work (RTW) outcomes. This systematic review aimed to summarize and evaluate the effects of clinical representative psychotherapy on ...
    • Examining 3-month test-retest reliability and reliable change using the Cambridge Neuropsychological Test Automated Battery 

      Karlsen, Rune Hatlestad; Karr, Justin E.; Saksvik, Simen Berg; Lundervold, Astri J.; Hjemdal, Odin; Olsen, Alexander; Iverson, Grant L.; Skandsen, Toril (Peer reviewed; Journal article, 2020)
      The Cambridge Neuropsychological Test Automated Battery (CANTAB) is a battery of computerized neuropsychological tests commonly used in Europe in neurology and psychiatry studies, including clinical trials. The purpose of ...
    • Examining differences in placental efficiency following exposure to antidepressants and current depression: Findings from an Australian pregnancy cohort study 

      Galbally, Megan; Watson, Stuart J.; Spigset, Olav; Lappas, Martha; Walker, Susan; Lewis, Andrew J. (Peer reviewed; Journal article, 2022)
      Introduction Placental dysfunction and inefficiency, is important in understanding fetal growth restriction and low birth weight. Two recent studies have examined the relationship between antidepressant use in pregnancy ...
    • Examining the educational impact of the mini-CEX: a randomised controlled study 

      Smeby, Susanne Skjervold; Espeland, Torvald; Berg, Erik Andreas Rye; Samstad, Eivind; Lillebo, Børge; Slørdahl, Tobias Schmidt (Journal article; Peer reviewed, 2021)
      Background: The purpose of this study is to evaluate the mini-Clinical Evaluation Exercise (mini-CEX) as a formative assessment tool among undergraduate medical students, in terms of student perceptions, effects on direct ...