Blar i St. Olavs hospital på tittel
Viser treff 28-47 av 2579
-
A small molecule activator of AKT does not reduce ischemic injury of the rat heart
(Journal article; Peer reviewed, 2015)Background Activation of protein kinase AKT is required for cardioprotection by ischemic preconditioning, and transgenic overexpression of AKT protects the heart against ischemia. However, it is unknown whether acute ... -
ABCD3-I and ABCD2 Scores in a TIA Population with Low Stroke Risk
(Peer reviewed; Journal article, 2021)Objectives. We aimed to evaluate the ABCD3-I score and compare it with the ABCD2 score in short- (1 week) and long-term (3 months; 1 year) stroke risk prediction in our post-TIA stroke risk study, MIDNOR TIA. Materials and ... -
Abdominal aerobic endurance exercise reveals spot reduction exists : a randomized controlled trial
(Peer reviewed; Journal article, 2023)The existence of spot reduction, exercise-induced local body fat reduction, has been debated for half a century. Although the evidence is equivocal, no study has applied aerobic endurance training closely matching interventions ... -
Absent exercise-induced improvements in fat oxidation in women with polycystic ovary syndrome after high-intensity interval training
(Peer reviewed; Journal article, 2021)Background: Polycystic ovary syndrome (PCOS) and metabolic inflexibility are linked to insulin resistance, and women with PCOS appear to be metabolic inflexible in the rested, insulin-stimulated state. Exercise training ... -
Absorption and pharmacokinetics of bupivacaine after bilateral topical administration in tonsillar fossae for posttonsillectomy pain relief
(Journal article; Peer reviewed, 2024)No previous studies have investigated the systemic absorption of bupivacaine when used topically for posttonsillectomy pain. The present study was undertaken to investigate the pharmacokinetics of bupivacaine after ... -
Abusive episodes among home-dwelling persons with dementia and their informal caregivers: a cross-sectional Norwegian study
(Peer reviewed; Journal article, 2022)Background: Elder abuse is a serious issue with a global prevalence of 15.7% in the community setting. Persons with dementia are at higher risk of elder abuse than the older population in general. With a high and increasing ... -
Academic detailing as a method to improve general practitioners’ drug prescribing in type 2 diabetes: evaluation of changes in prescribing
(Peer reviewed; Journal article, 2023)Objective To investigate the effect of an academic detailing intervention on the utilisation of type 2 diabetes medication among general practitioners. Design We developed an academic detailing campaign based on the ... -
Accelerometer-measured physical activity at 3 months as a predictor of symptoms of depression and anxiety 1 year after stroke: a multicentre prospective cohort study in central Norway
(Peer reviewed; Journal article, 2023)Objectives: To study sedentary behaviour and physical activity at 3 months as predictors for symptoms of depression and anxiety at 1-year post-stroke. Design: A prospective cohort study. Patients: Patients with ... -
Acceptability and feasibility of enhanced cognitive behavioral therapy (eCBT) for children and adolescents with obsessive–compulsive disorder
(Peer reviewed; Journal article, 2021)Introduction Obsessive–compulsive disorder (OCD) is a disabling mental health disorder affecting 1–3% of children and adolescents. Cognitive behavioral therapy (CBT) is recommended as the first-line treatment, but is limited ... -
Acceptance and commitment therapy (ACT) for professional staff burnout: a systematic review and narrative synthesis of controlled trials
(Peer reviewed; Journal article, 2022)Background: Staff working in people-oriented professions are vulnerable to burnout which is negatively associated with professional well-being and service-user care. Aim: To investigate if interventions based on Acceptance ... -
Acceptance and use of a clinical decision support system in musculoskeletal pain disorders – the SupportPrim project
(Journal article; Peer reviewed, 2023)Background We have developed a clinical decision support system (CDSS) based on methods from artificial intelligence to support physiotherapists and patients in the decision-making process of managing musculoskeletal (MSK) ... -
Access site complications after transfemoral aortic valve implantation - a comparison of Manta and ProGlide
(Journal article, 2018)Background: Despite decreasing sheath diameter, access site bleeding and vascular complications are still a major concern in transfemoral aortic valve implantation (TAVI), and may increase morbidity and even increase ... -
Accuracy and Complication Rates of External Ventricular Drain Placement With Twist Drill and Bolt System Versus Standard Trephine and Tunnelation: A Retrospective Population-Based Study
(Peer reviewed; Journal article, 2020)Background: An external ventricular drain (EVD) is typically indicated in the presence of hydrocephalus and increased intracranial pressure (ICP). Procedural challenges have prompted the development of different methods ... -
Accuracy of breast cancer lesion classification using intravoxel incoherent motion diffusion-weighted imaging is improved by the inclusion of global or local prior knowledge with bayesian methods
(Journal article; Peer reviewed, 2019)Background Diffusion‐weighted MRI (DWI) has potential to noninvasively characterize breast cancer lesions; models such as intravoxel incoherent motion (IVIM) provide pseudodiffusion parameters that reflect tissue perfusion, ... -
Accuracy of neuropathic pain measurements in patients with symptoms of polyneuropathy: validation of painDETECT, Self-Completed Leeds Assessment of Neuropathic Symptoms and Signs, and Douleur Neuropathique 4
(Peer reviewed; Journal article, 2022)Pain is a common symptom in patients referred to polyneuropathy assessment. Diagnostic evaluation and choice of treatment may depend on whether the pain is likely to be neuropathic or not. This study aimed to investigate ... -
ACL Reconstruction Patients Have Increased Risk of Knee Arthroplasty at 15 Years of Follow-up : Data from the Norwegian Knee Ligament Register and the Norwegian Arthroplasty Register from 2004 to 2020
(Peer reviewed; Journal article, 2022)Background: Anterior cruciate ligament (ACL) injury is considered a risk factor for osteoarthritis. The primary aim of the present study was to investigate the cumulative risk of, and risk factors associated with, a ... -
Actigraphy assessment of motor activity and sleep in patients with alcohol withdrawal syndrome and the effects of intranasal oxytocin
(Peer reviewed; Journal article, 2020)Background and aims The alcohol withdrawal syndrome increases autonomic activation and stress in patients during detoxification, leading to alterations in motor activity and sleep irregularities. Intranasal oxytocin has ... -
Active conventional treatment and three different biological treatments in early rheumatoid arthritis: Phase IV investigator initiated, randomised, observer blinded clinical trial
(Peer reviewed; Journal article, 2020)Objective To evaluate and compare benefits and harms of three biological treatments with different modes of action versus active conventional treatment in patients with early rheumatoid arthritis. Design Investigator ... -
Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors
(Peer reviewed; Journal article, 2020)Activins belong to the transforming growth factor (TGF)-β family of multifunctional cytokines and signal via the activin receptors ALK4 or ALK7 to activate the SMAD2/3 pathway. In some cases, activins also signal via the ...