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The HUNT4 study: the validity of questionnaire-based diagnoses
(Journal article; Peer reviewed, 2019)Background Questionnaire-based headache diagnoses should be validated against diagnoses made by the gold standard, which is personal interview by a headache expert. The diagnostic algorithm with the best diagnostic accuracy ... -
The impact of C-reactive protein levels on headache frequency in the HUNT study 2006-2008
(Journal article; Peer reviewed, 2019)Background Increased high sensitivity C- reactive protein (hs-CRP) levels have been found in many earlier studies on migraine, and recently also in persons with migraine and insomnia. The aim of this study was to see ... -
The impact of headache and chronic musculoskeletal complaints on the risk of insomnia: longitudinal data from the Nord-Trondelag health study
(Journal article; Peer reviewed, 2013)Background A strong relationship between insomnia and painful disorders has been found, but it is still unclear whether chronic pain leads to insomnia. There is a need of large-scale prospective studies to evaluate if ... -
The impact of headache in Europe: principal results of the Eurolight project
(Journal article; Peer reviewed, 2014)Background European data, at least from Western Europe, are relatively good on migraine prevalence but less sound for tension-type headache (TTH) and medication-overuse headache (MOH). Evidence on impact of headache ... -
The Impact of the West Africa Ebola Outbreak on Obstetric Health Care in Sierra Leone
(Journal article; Peer reviewed, 2016)Background As Sierra Leone celebrates the end of the Ebola Virus Disease (EVD) outbreak, we can begin to fully grasp its impact on already weak health systems. The EVD outbreak in West Africa forced many hospitals to ... -
The incidence of diagnosis of Munchausen syndrome, other factitious disorders, and malingering
(Journal article; Peer reviewed, 2019)Background. Systematic studies on factitious disorders and malingering in large populations are rare. To address this issue, we performed a nationwide epidemiological study in Norway on the incidence of these diagnoses in ... -
The interplay between sleeplessness and high-sensitivity C-reactive protein on risk of chronic musculoskeletal pain: longitudinal data from the Tromsø Study
(Journal article; Peer reviewed, 2019)Study Objectives To examine independent associations of sleeplessness and high-sensitivity C-reactive protein (hsCRP) with risk of chronic musculoskeletal pain, and to explore the joint effect of sleeplessness and hsCRP ... -
The methodology of population surveys of headache prevalence, burden and cost: Principles and recommendations from the Global Campaign against Headache
(Journal article; Peer reviewed, 2014)The global burden of headache is very large, but knowledge of it is far from complete and needs still to be gathered. Published population-based studies have used variable methodology, which has influenced findings and ... -
The Norwegian PMS2 founder mutation c.989-1G>T shows high penetrance of microsatellite instable cancers with normal immunohistochemistry
(Journal article; Peer reviewed, 2014)Background Using immunohistochemistry (IHC) to select cases for mismatch repair (MMR) genetic testing, we failed to identify a large kindred with the deleterious PMS2 mutation c.989-1G > T. The purpose of the study was ... -
The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats
(Journal article; Peer reviewed, 2011)Background Activation of peroxisome proliferator-activated receptor (PPAR)gamma is associated with bone loss and increased fracture risk, while PPARalpha activation seems to have positive skeletal effects. To further ... -
The phylogeny and biological function of gastric juice-microbiological consequences of removing gastric acid
(Journal article; Peer reviewed, 2019)Gastric juice is a unique combination of hydrochloric acid (HCl), lipase, and pepsin. Acidic gastric juice is found in all vertebrates, and its main function is to inactivate microorganisms. The phylogenetic preservation ... -
The Predictive Accuracy of the General Movement Assessment for Cerebral Palsy: A Prospective, Observational Study of High-Risk Infants in a Clinical Follow-Up Setting
(Journal article; Peer reviewed, 2019)Background: Early prediction of cerebral palsy (CP) using the General Movement Assessment (GMA) during the fidgety movements (FM) period has been recommended as standard of care in high-risk infants. The aim of this study ... -
The rate and perioperative mortality of caesarean section in Sierra Leone
(Journal article; Peer reviewed, 2019)Introduction Sierra Leone has the world’s highest maternal mortality, partly due to low access to caesarean section. Limited data are available to guide improvement. In this study, we aimed to analyse the rate and mortality ... -
The regional research biobank of central Norway - "One biobank, many collections" :
(Journal article; Peer reviewed, 2012)The term biobank is used to designate a systematized collection of biological specimens, often restricted to specimens of human origin (1). Population biobanks, which mainly receive blood samples from large cohorts, have ... -
The relationship between headache and religious attendance (the Nord-Trøndelag health study-HUNT)
(Journal article; Peer reviewed, 2014)Background Religious belief can be used as a pain coping strategy. Our purpose was to evaluate the relationship between headache and religious activity using prospective data from a large population-based study. Meth ... -
The relationship of anxiety, depression and behavioral problems with recurrent headache in late adolescence - a Young-HUNT follow-up study
(Journal article; Peer reviewed, 2015)Background The comorbidity of headache and psychiatric symptoms is a well-recognized clinical phenomenon, but there are only limited data regarding the temporal relationship between headache and symptoms of anxiety and ... -
The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease
(Journal article; Peer reviewed, 2018)Accumulating evidence demonstrating higher cerebrospinal fluid (CSF) α-synuclein (αSyn) levels and αSyn pathology in the brains of Alzheimer’s disease (AD) patients suggests that αSyn is involved in the pathophysiology of ... -
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
(Journal article; Peer reviewed, 2019)Phagocytosis is a complex process that eliminates microbes and is performed by specialised cells such as macrophages. Toll-like receptor 4 (TLR4) is expressed on the surface of macrophages and recognizes Gram-negative ... -
Thoracic Radiotherapy in Limited-Stage SCLC—a Population-Based Study of Patterns of Care in Norway From 2000 Until 2018
(Peer reviewed; Journal article, 2022)Introduction Twice-daily (BID) thoracic radiotherapy (TRT) of 45 Gy per 30 fractions is recommended for limited-stage (LS) SCLC, but most patients are treated with once-daily (OD) schedules owing to toxicity concerns ... -
Three groups of suspects in police-reported rape cases: First-time suspects, recidivists and unidentified suspects. A comparative study
(Peer reviewed; Journal article, 2019)Background Previous studies show that reported suspects in adult rape cases often have a criminal record, and that many are rape recidivists. Annual numbers of police reported rapes have dramatically increased but the ...