Blar i St. Olavs hospital på tittel

Viser treff 1479-1498 av 2530

    • Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation 

      Niyonzima, Nathalie; Rahman, Jubayer; Kunz, Natalie; West, Erin; Freiwald, Tilo; Desai, Jigar V.; Merle, Nicolas; Gidon, Alexandre; Sporsheim, Bjørnar; Lionakis, Michail S.; Evensen, Kristin; Lindberg, Beate; Skagen, Karolina; Skjelland, Mona; Singh, Parul; Haug, Markus; Ruseva, Marieta M.; Kolev, Martin; Bibby, Jack; Marshall, Olivia; O’Brien, Brett; Deeks, Nigel; Afzali, Behdad; Clark, Richard J.; Woodruff, Trent M.; Pryor, Mylton; Yang, Zhi-Hong; Remaley, Alan T.; Mollnes, Tom Eirik; Hewitt, Stephen M.; Yan, Bingyu; Kazemian, Majid; Kiss, Mate G.; Binder, Christoph J.; Halvorsen, Bente; Espevik, Terje; Kemper, Claudia (Peer reviewed; Journal article, 2021)
      While serum-circulating complement destroys invading pathogens, intracellularly active complement, termed the “complosome,” functions as a vital orchestrator of cell-metabolic events underlying T cell effector responses. ...

    • Mitochondrial genome-wide association study of migraine – the HUNT Study 

      Børte, Sigrid; Zwart, John-Anker; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Thomas, Laurent; Fritsche, Lars G; Surakke, Ida; Nielsen, Jonas B.; Zhou, Wei; Wolford, Brooke; Vigeland, Magnus Dehli; Hagen, Knut; Kristoffersen, Espen Saxhaug; Nyholt, Dale R; Chasman, Daniel I; Brumpton, Ben Michael; Willer, Christen; Winsvold, Bendik K S (Peer reviewed; Journal article, 2020)
      Background Variation in mitochondrial DNA (mtDNA) has been indicated in migraine pathogenesis, but genetic studies to date have focused on candidate variants, with sparse findings. We aimed to perform the first mitochondrial ...

    • Mitochondrial Mechanisms of LRRK2 G2019S Penetrance 

      Delcambre, Sylvie; Ghelfi, Jenny; Ouzren, Nazzima; Grandmougin, Lea; Delbrouck, Catherine; Seibler, Philip; Wasner, Kobi; Aasly, Jan; Klein, Christine; Trinh, Joanne; Pereira, Sandro L; Grünewald, Anne (Peer reviewed; Journal article, 2020)
      Several mutations in leucine-rich repeat kinase-2 (LRRK2) have been associated with Parkinson's disease (PD). The most common substitution, G2019S, interferes with LRRK2 kinase activity, which is regulated by autophosphorylation. ...

    • Mixed reality training application to perform obstetric pulsed-wave Doppler ultrasound 

      Nylund, Maria Emine; Jain, Shubham; Tegnander, Eva; Jensen, Eva Johanne Leknes; Prasolova-Førland, Ekaterina; Lindseth, Frank; Kiss, Gabriel Hanssen (Peer reviewed; Journal article, 2023)
      Pulsed-wave Doppler ultrasound is a widely used technique for monitoring pregnancies. As ultrasound equipment becomes more advanced, it becomes harder to train practitioners to be proficient in the procedure as it requires ...

    • Mn-alginate gels as a novel system for controlled release of Mn2+ in manganese-enhanced MRI 

      Mørch, Yrr Asbjørg; Sandvig, Ioanna; Olsen, Øystein; Donati, Ivan; Thuen, Marte; Skjåk-Bræk, Gudmund; Haraldseth, Olav; Brekken, Christian (Journal article; Peer reviewed, 2012)
      The aim of the present study was to test alginate gels of different compositions as a system for controlled release of manganese ions (Mn2+) for application in manganese‐enhanced MRI (MEMRI), in order to circumvent the ...

    • Mobile Assessments of Mood, Cognition, Smartphone-Based Sensor Activity, and Variability in Craving and Substance Use in Patients With Substance Use Disorders in Norway: Prospective Observational Feasibility Study 

      Lauvsnes, Anders Dahlen Forsmo; Hansen, Tor Ivar; Ankill, Sebastian Øiungen; Bae, Sang Won; Gråwe, Rolf W.; Braund, Taylor A.; Larsen, Mark; Langaas, Mette (Peer reviewed; Journal article, 2023)
      Background: Patients with substance use disorders (SUDs) are at increased risk for symptom deterioration following treatment, with up to 60% resuming substance use within the first year posttreatment. Substance use craving ...

    • Mobile Sensing in Substance Use Research: A Scoping Review 

      Lauvsnes, Anders Dahlen Forsmo; Langaas, Mette; Toussaint, Pieter Jelle; Gråwe, Rolf W. (Peer reviewed; Journal article, 2020)
      Background:Addictive disorders and substance use are significant health challenges worldwide, and relapse is a core component of addictive disorders. The dynamics surrounding relapse and especially the immediate period ...

    • Mode of delivery of Cognitive Behavioral Therapy for Insomnia: a randomized controlled non-inferiority trial of digital and face-to-face therapy 

      Kallestad, Håvard; Scott, Janine Linda; Vedaa, Øystein; Lydersen, Stian; Vethe, Daniel; Morken, Gunnar; Stiles, Tore C; Sivertsen, Børge; Langsrud, Knut (Peer reviewed; Journal article, 2021)
      Study Objectives Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I) has demonstrated efficacy in reducing insomnia severity in self-referred and community samples. It is unknown, however, how dCBT-I compares to ...

    • Modeling Obesity in Norway (The MOON Study): A Decision-Analytic Approach—Prevalence, Costs, and Years of Life Lost 

      Bjørnelv, Gudrun Maria Waaler; Halsteinli, Vidar; Kulseng, Bård Eirik; Sonntag, Diana; Ødegård, Rønnaug (Peer reviewed; Journal article, 2020)
      Background. Limited knowledge exists on the expected long-term effects and cost-effectiveness of initiatives aiming to reduce the burden of obesity. Aim. To develop a Norwegian obesity-focused disease-simulation model: the ...

    • Modeling the diffusion-weighted imaging signal for breast lesions in the b = 200 to 3000 s/mm 2 range: quality of fit and classification accuracy for different representations 

      Vidic, Igor; Egnell, Liv Elisabet; Jerome, Neil Peter; White, Nathan; Karunamuni, Roshan; Rakow-Penner, Rebecca; Dale, Anders M.; Bathen, Tone Frost; Goa, Pål Erik (Peer reviewed; Journal article, 2020)
      Purpose To evaluate different non‐Gaussian representations for the diffusion‐weighted imaging (DWI) signal in the b‐value range 200 to 3000 s/mm2 in benign and malignant breast lesions. Methods Forty‐three patients ...

    • Models, frameworks and theories in the implementation of programs targeted to reduce formal coercion in mental health settings: a systematic review 

      Lantta, Tella; Duxbury, Joy; Haines-Delmont, Alina; Björkdahl, Anna; Husum, Tonje Lossius; Lickiewicz, Jakub; Douzenis, Athanassios; Craig, Elaine; Goodall, Katie; Bora, Christina; Whyte, Rachel; Whittington, Richard Charles (Peer reviewed; Journal article, 2023)
      Introduction: Implementation models, frameworks and theories (hereafter tools) provide researchers and clinicians with an approach to understand the processes and mechanisms for the successful implementation of healthcare ...

    • Moderate and severe traumatic brain injury in general hospitals: a ten-year population-based retrospective cohort study in central Norway 

      Rahim, Shavin; Laugsand, Eivor Alette; Fyllingen, Even Hovig; Rao, Vidar; Pantelatos, Rabea Iris; Müller, Tomm Brostrup; Vik, Anne; Skandsen, Toril (Peer reviewed; Journal article, 2022)
      Background Patients with moderate and severe traumatic brain injury (TBI) are admitted to general hospitals (GHs) without neurosurgical services, but few studies have addressed the management of these patients. This ...

    • Moderate continuous or high intensity interval exercise in heart failure with reduced ejection fraction: Differences between ischemic and non-ischemic etiology 

      Halle, Martin; Prescott, Eva Bossano; Craenenbroeck, Emeline M Van; Beckers, Paul; Videm, Vibeke; Karlsen, Trine; Feiereisen, Patrick; Winzer, Ephraim B.; Mangner, Norman; Snoer, Martin; Christle, Jeffrey W.; Dalen, Håvard; Støylen, Asbjørn; Esefeld, Katrin; Heitkamp, Melanie; Spanier, Bianca; Axel, Linke; Ellingsen, Øyvind; Delagardelle, Charles (Peer reviewed; Journal article, 2022)
      Background Exercise for heart failure (HF) with reduced ejection fraction (HFrEF) is recommended by guidelines, but exercise mode and intensities are not differentiated between HF etiologies. We, therefore, investigated ...

    • Moderately increased albuminuria, chronic kidney disease and incident dementia: the HUNT study 

      Gabin, Jessica Mira; Romundstad, Solfrid; Saltvedt, Ingvild; Holmen, Jostein (Journal article; Peer reviewed, 2019)
      Background Epidemiologic studies has shown an association of albuminuria and low estimated glomerular filtration rate (eGFR) with dementia, but the findings are inconsistent. This study examines the association between ...

    • Modes of e-Health delivery in secondary prevention programmes for patients with coronary artery disease: A systematic review 

      Brørs, Gunhild; Pettersen, Trond Røed; Hansen, Tina B.; Fridlund, Bengt Gotthard Anton; Hølvold, Linn Benjaminsen; Lund, Hans; Norekvål, Tone M. (Peer reviewed; Journal article, 2019)
      Background: Electronic health (e-Health) interventions are emerging as an effective alternative model for improving secondary prevention of coronary artery disease (CAD). The aim of this study was to describe the effectiveness ...

    • Modifiable factors affecting older patients' quality of life and physical function during cancer treatment 

      Kirkhus, Lene; Harneshaug, Magnus; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Bergh, Sverre; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Kirkevold, Øyvind; Borza, Tom; Saltvedt, Ingvild; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)
      Background Maintaining physical function and quality of life (QoL) are prioritized outcomes among older adults. We aimed to identify potentially modifiable factors affecting older patients' physical function and QoL ...

    • Modified prolonged exposure therapy as Early Intervention after Rape (The EIR-study): study protocol for a multicenter randomized add-on superiority trial 

      Haugen, Tina; Halvorsen, Joar Øveraas; Friborg, Oddgeir; Simpson, Melanie Rae; Mork, Paul Jarle; Mikkelsen, Gustav; Elklit, Ask; Rothbaum, Barbara O.; Schei, Berit; Hagemann, Cecilie Therese (Peer reviewed; Journal article, 2023)
      Background Sexual assault and rape are the traumatic life events with the highest probability for posttraumatic stress disorder (PTSD), which can have devastating consequences for those afflicted by the condition. Studies ...

    • The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms 

      Venizelos, Andreas; Elvebakken, Hege; Perren, Aurel; Nikolaienko, Oleksii; Deng, Wei; Lothe, Inger Marie Bowitz; Couvelard, Anne; Hjortland, Geir Olav; Sundlöv, Anna; Svensson, Johanna; Garresori, Herish; Kersten, Christian; Hofsli, Eva; Detlefsen, Sönke; Krogh, Merete; Sørbye, Halfdan; Knappskog, Stian (Peer reviewed; Journal article, 2021)
      High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare but have a very poor prognosis and represent a severely understudied class of tumours. Molecular data for HG GEP-NEN are limited, and ...

    • Molecular status 36 months after TKI discontinuation in CML is highly predictive for subsequent loss of MMR—final report from AFTER-SKI 

      Richter, Johan; Lübking, Anna; Söderlund, Stina; Lotfi, Kourosh; Markevärn, Berit; Själander, Anders; Stenke, Leif; Deneberg, Stefan; Ahlstrand, Erik; Myhr-Eriksson, Kristina; Panayiotidis, Panayiotis; Gedde-Dahl, Tobias; Žáčková, Daniela; Mayer, Jiří; Olsson-Strömberg, Ulla; Mahon, Francois-Xavier; Saussele, Susanne; Hjorth-Hansen, Henrik; Koskenvesa, Perttu (Peer reviewed; Journal article, 2021)

    • More than just a bed: Mental health service users' experiences of self-referral admission 

      Olsø, Turid Møller; Gudde, Camilla Buch; Moljord, Inger Elise Opheim; Evensen, Gretha Helen; Antonsen, Dag Øivind; Eriksen, Lasse (Peer reviewed; Journal article, 2016)
      Background Several community mental health centres and mental hospitals in Norway now allow users with a diagnosis of severe mental illness to self-refer for admission. This give a group of service users who are well-known ...