Blar i St. Olavs hospital på tittel
Viser treff 1466-1485 av 2460
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Motor activity across delirium motor subtypes in geriatric patients assessed using body-worn sensors: a Norwegian cross-sectional study
(Journal article; Peer reviewed, 2019)Objectives It remains unclear if geriatric patients with different delirium motor subtypes express different levels of motor activity. Thus, we used two accelerometer-based devices to simultaneously measure upright activity ... -
Moving ferromagnetic objects distorting cardiac magnetic resonance imaging
(Peer reviewed; Journal article, 2020) -
MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment
(Journal article; Peer reviewed, 2019)Childhood neuroblastoma is a hypervascular tumor of neural origin, for which antiangiogenic drugs are currently being evaluated; however, predictive biomarkers of treatment response, crucial for successful delivery of ... -
MRI in the Assessment of TMJ-Arthritis in Children with JIA; Repeatability of a Newly Devised Scoring System
(Peer reviewed; Journal article, 2021)Rationale and Objectives: The temporomandibular joint (TMJ) is commonly involved in children with juvenile idiopathic arthritis. The diagnosis and evaluation of the disease progression is dependent on medical imaging. The ... -
MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study
(Peer reviewed; Journal article, 2021)Background - The concept of the use of MRI for image-guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer was introduced 20 years ago. Here, we report on EMBRACE-I, which aimed to evaluate local tumour ... -
MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes
(Peer reviewed; Journal article, 2020)Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 ... -
MRSA-forekomst blant helsepersonell ved smitteoppsporing i sykehus
(Peer reviewed; Journal article, 2018) -
MTHFR C677T and A1298C polymorphism’s effect on risk of colorectal cancer in Lynch syndrome
(Peer reviewed; Journal article, 2023)Lynch syndrome (LS) is characterised by an increased risk of developing colorectal cancer (CRC) and other extracolonic epithelial cancers. It is caused by pathogenic germline variants in DNA mismatch repair (MMR) genes or ... -
Mucosal 5-aminosalicylic acid concentration, drug formulation and mucosal microbiome in patients with quiescent ulcerative colitis
(Journal article; Peer reviewed, 2019)Background 5‐aminosalicylic acid (5‐ASA) is the first‐line therapy for ulcerative colitis (UC). 5‐ASA acts locally in the colonic mucosa by numerous proposed mechanisms, and is metabolised by N‐acetyltransferase (NAT). ... -
Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis
(Peer reviewed; Journal article, 2021)Background Collagenous colitis (CC) is an inflammatory bowel disease where chronic diarrhoea is the main symptom. Diagnostic markers distinguishing between CC and other causes of chronic diarrhoea remain elusive. This study ... -
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
(Peer reviewed; Journal article, 2023)Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 ... -
Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries
(Peer reviewed; Journal article, 2023)Stroke is the second leading cause of death and disability worldwide. Stroke prevalence varies by sex and ancestry, possibly due to genetic heterogeneity between subgroups. We performed a genome-wide meta-analysis of 16 ... -
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
(Peer reviewed; Journal article, 2022)A major challenge of genome-wide association studies (GWASs) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ... -
Multi-modal characterization of vasculature and nanoparticle accumulation in five tumor xenograft models
(Journal article; Peer reviewed, 2018)Preclinical research has demonstrated that nanoparticles and macromolecules can accumulate in solid tumors due to the enhanced permeability and retention effect. However, drug loaded nanoparticles often fail to show increased ... -
Multi-timescale microscopy methods for the characterization of fluorescently-labeled microbubbles for ultrasound-triggered drug release
(Peer reviewed; Journal article, 2021)Microbubble contrast agents hold great promise for drug delivery applications with ultrasound. Encapsulating drugs in nanoparticles reduces systemic toxicity and increases circulation time of the drugs. In a novel approach ... -
Multifactorial assessment of Parkinson’s disease course and outcomes using trajectory modeling in a multiethnic, multisite cohort – extension of the LONG-PD study
(Peer reviewed; Journal article, 2023)Background: The severity, progression, and outcomes of motor and non-motor symptoms in Parkinson’s disease (PD) are quite variable. Following PD cohorts holds promise for identifying predictors of disease severity and ... -
Multimodal Analysis of Secondary Cerebellar Alterations After Pediatric Traumatic Brain Injury
(Peer reviewed; Journal article, 2023)IMPORTANCE: Traumatic brain injury (TBI) is known to cause widespread neural disruption in the cerebrum. However, less is known about the association of TBI with cerebellar structure and how such changes may alter executive ... -
Multimodal individualised intervention to prevent functional decline after stroke: protocol of a randomised controlled trial on long-term follow-up after stroke (LAST-long)
(Peer reviewed; Journal article, 2023)Introduction Multimodal interventions have emerged as new approaches to provide more targeted intervention to reduce functional decline after stroke. Still, the evidence is contradictory. The main objective of the Life ... -
A multiomics disease progression signature of low-risk ccRCC
(Peer reviewed; Journal article, 2022)Clear cell renal cell carcinoma (ccRCC) is the most common renal cancer. Identification of ccRCC likely to progress, despite an apparent low risk at the time of surgery, represents a key clinical issue. From a cohort of ...