• Incidence of the diagnosis of factitious disorders - Nationwide comparison study between Germany and Norway 

      Geile, Julian; Aasly, Jan; Madea, Burkhard; Schrader, Harald (Peer reviewed; Journal article, 2020)
      Factitious disorders (FD) like Munchausen syndrome are well known to most physicians, yet the corresponding ICD-10 diagnosis F68.1 remains severely under-assigned and often misdiagnosed. To approach this problem, we conducted ...
    • Incidence of thrombotic complications in hospitalised and non-hospitalised patients after COVID-19 diagnosis 

      Tholin, Birgitte; Ghanima, Waleed Khalid; Einvik, Gunnar; Aarli, Bernt Bøgvald; Brønstad, Eivind; Skjønsberg, Ole Henning; Stavem, Knut (Peer reviewed; Journal article, 2021)
      Infection with coronavirus disease-2019 (COVID-19) may predispose for venous thromboembolism (VTE). There is wide variation in reported incidence rates of VTE in COVID-19, ranging from 3% to 85%. Therefore, the true incidence ...
    • Incidence of Young Onset Dementia in Central Norway: A Population-Based Study 

      Kvello-Alme, Marte; Bråthen, Geir; White, Linda Rosemary; Sando, Sigrid Botne (Peer reviewed; Journal article, 2020)
      Background: The epidemiology of young onset dementia is little researched compared to late onset dementia. Information on incidence rates is vital for medical professionals, and for government planning purposes. Objective: ...
    • Incidence, Mechanisms of Injury and Mortality of Severe Traumatic Brain Injury: An Observational Population-Based Cohort Study from New Zealand and Norway 

      Weber, Clemens; Andreassen, Joakim Stray; Isles, Siobhan; Thorsen, Kenneth; McBride, Paul; Søreide, Kjetil; Civil, Ian (Peer reviewed; Journal article, 2022)
      Background - Comparing trauma registry data from different countries can help to identify possible differences in epidemiology, which may help to improve the care of trauma patients. Methods - This study directly compares ...
    • Incidence, recurring admissions and mortality of severe bacterial infections and sepsis over a 22-year period in the population-based HUNT study 

      Liyanarachi, Kristin Vardheim; Solligård, Erik; Mohus, Randi Marie; Åsvold, Bjørn Olav; Rogne, Tormod; Damås, Jan Kristian (Peer reviewed; Journal article, 2022)
      Purpose Severe bacterial infections are important causes of hospitalization and loss of health worldwide. In this study we aim to characterize the total burden, recurrence and severity of bacterial infections in the ...
    • An incomplete Circle of Willis is not a risk factor for white matter hyperintensities: The Tromsø Study 

      Hindenes, Lars Bakke; Håberg, Asta Kristine; Mathiesen, Ellisiv B; Vangberg, Torgil Riise (Peer reviewed; Journal article, 2020)
      Objective The Circle of Willis (CoW) is often underdeveloped or incomplete, leading to suboptimal blood supply to the brain. As hypoperfusion is thought to play a role in the aetiology of white matter hyperintensities ...
    • Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies 

      Syrogiannouli, Lamprini; Wildisen, Lea; Meuwese, Christiaan; Bauer, Douglas C.; Cappola, Anne R.; Gussekloo, Jacobijn; den Elzen, Wendy P. J.; Trompet, Stella; Westendorp, Rudi G. J.; Jukema, J. Wouter; Ferrucci, Luigi; Ceresini, Graziano; Åsvold, Bjørn Olav; Chaker, Layal; Peeters, Robin P.; Imaizumi, Misa; Ohishi, Waka; Vaes, Bert; Völzke, Henry; Sgarbi, Josè A.; Walsh, John P.; Dullaart, Robin P. F.; Bakker, Stephan J. L.; Iacoviello, Massimo; Rodondi, Nicolas; Del Giovane, Cinzia (Peer reviewed; Journal article, 2022)
      Background: In non-randomized studies (NRSs) where a continuous outcome variable (e.g., depressive symptoms) is assessed at baseline and follow-up, it is common to observe imbalance of the baseline values between the ...
    • Increase in curative treatment and survival of lung cancer in Norway 2001-2016 

      Solberg, Steinar; Nilssen, Yngvar; Brustugun, Odd Terje; Grimsrud, Tom Kristian; Haram, Per Magnus; Helbekkmo, Nina; Helland, Åslaug; Hjelde, Harald Harris; Jakobsen, Bjørn; Møller, Bjørn; Petersen, Martin; Strand, Trond-Eirik; Wahl, Sissel Gyrid Freim; Aanerud, Marianne; Fjellbirkeland, Lars (Peer reviewed; Journal article, 2019)
      We have studied the alterations in the use of curative treatment and the outcome for lung cancer patients in Norway 2001–2016. The Cancer Registry of Norway has a practically complete registration of all cancer diagnoses, ...
    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O’Connell, Kevin; Ueland, Thor; Ahmed, Mashhood Sheikh; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John Abel; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Auten Weibell, Melissa; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2022)
      Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...
    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O'Connell, Kevin Sean; Ueland, Thor; Sheikh, Mashhood Ahmed; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2021)
      Background -Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...
    • Increased deformation of the left ventricle during exercise test measured by global longitudinal strain can rule out significant coronary artery disease in patients with suspected unstable angina pectoris 

      Karlsen, Sigve; Melichova, Daniela; Dahlslett, Thomas; Grenne, Bjørnar; Sjøli, Benthe; Smiseth, Otto A.; Edvardsen, Thor; Brunvand, Harald (Peer reviewed; Journal article, 2022)
      Background Noninvasive identification of significant coronary artery disease (CAD) in patients with unstable angina pectoris (UAP) is challenging. Exercise stress testing has been used for years in patients with suspected ...
    • Increased expression of individual genes in whole blood is associated with late-stage lung cancer at and close to diagnosis 

      Urbarova, Ilona Halva; Skogholt, Anne Heidi; Sun, Yi-Qian; Mai, Xiao-Mei; Grønberg, Bjørn Henning; Sandanger, Torkjel Manning; Sætrom, Pål; Nøst, Therese Haugdahl (Peer reviewed; Journal article, 2023)
      Lung cancer (LC) mortality rates are still increasing globally. As survival is linked to stage, there is a need to identify markers for earlier LC diagnosis and individualized treatment. The whole blood transcriptome of ...
    • Increased incidence of inflammatory bowel disease on etanercept in juvenile idiopathic arthritis regardless of concomitant methotrexate use 

      van Straalen, Joeri W.; Krol, Roline; Giancane, Gabriella; Panaviene, Violeta; Ailioaie, Laura Marinela; Dolezalova, Pavla; Cattalini, Marco; Susic, Gordana; Sztajnbok, Flavio; Maritsi, Despoina; Constantin, Tamas; Sawhney, Sujata; Rygg, Marite; Oliveira, Sheila K.; Nordal, Ellen Berit; Saad-Magalhaes, C; Rubio-Perez, Nadina; Jelusic, Marija; de Roock, Sytze; Wulffraat, Nico; Ruperto, Nicolino; Swart, Joost Frans; International Trials Org, Paediatric Rheumatology (Peer reviewed; Journal article, 2021)
      Objectives: To describe risk factors for inflammatory bowel disease (IBD) development in a cohort of children with juvenile idiopathic arthritis (JIA). Methods: JIA patients who developed IBD were identified from the ...
    • Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer 

      Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael; Johansson, Mattias; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål (Peer reviewed; Journal article, 2022)
      Lung cancer (LC) incidence is increasing globally and altered levels of microRNAs (miRNAs) in blood may contribute to identification of individuals with LC. We identified miRNAs differentially expressed in peripheral blood ...
    • Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer 

      Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael; Johansson, Mattias; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål (Peer reviewed; Journal article, 2022)
      Lung cancer (LC) incidence is increasing globally and altered levels of microRNAs (miRNAs) in blood may contribute to identification of individuals with LC. We identified miRNAs differentially expressed in peripheral blood ...
    • Increased long-term risk for hypertension in kidney donors – a retrospective cohort study 

      Haugen, Anders Johan Smedman; Hallan, Stein; Langberg, Nina Elisabeth Borthen; Dahle, Dag Olav; Pihlstrøm, Hege; Birkeland, Kåre I.; Reisæter, Anna Varberg; Midtvedt, Karsten; Hartmann, Anders; Holdaas, Hallvard; Mjøen, Geir (Peer reviewed; Journal article, 2020)
      Kidney donors may be at increased risk of end-stage renal disease and premature mortality. Elevated blood pressure after donation may contribute to the increased risks. In this cohort study, we have assessed long-term risk ...
    • Increased membrane Ca<sup>2+</sup> permeability drives astrocytic Ca<sup>2+</sup> dynamics during neuronal stimulation at excitatory synapses 

      Hjukse, Jarand Berg; Fernández de la Puebla, Mario; Vindedal, Gry Fluge; Sprengel, Rolf; Jensen, Vidar; Nagelhus, Erlend Arnulf; Tang, Wannan (Peer reviewed; Journal article, 2023)
      Astrocytes are intricately involved in the activity of neural circuits; however, their basic physiology of interacting with nearby neurons is not well established. Using two-photon imaging of neurons and astrocytes during ...
    • Increased mortality in hip fracture patients living alone: A NOREPOS study 

      Dahl, Cecilie; Holvik, Kristin; Meyer, Haakon E; Stigum, Hein; Solbakken, Siri Marie; Schei, Berit; Søgaard, Anne Johanne; Omsland, Tone Kristin (Peer reviewed; Journal article, 2021)
      Hip fracture is associated with excess mortality, persisting for many years after the fracture. Several factors may affect survival; however, the role of social support has been less studied. Living situation could be an ...
    • Increased Mortality in Young-Onset Parkinson's Disease 

      Hustad, Eldbjørg; Myklebust, Tor Åge; Gulati, Sasha; Aasly, Jan (Peer reviewed; Journal article, 2021)
      Objective Few studies have followed Parkinson’s disease (PD) patients from the time of diagnosis to the date of death. This study compared mortality in the Trondheim PD cohort to the general population, investigated causes ...
    • Increased Oxidative Stress Markers in Cerebrospinal Fluid from Healthy Subjects with Parkinson's Disease-Associated LRRK2 Gene Mutations 

      Loeffler, David A.; Klaver, Andrea C.; Coffey, Mary P.; Aasly, Jan; LeWitt, Peter A. (Peer reviewed; Journal article, 2017)
      Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of inherited Parkinson’s disease (PD). The most common PD-associated LRRK2 mutation, G2019S, induces increased production of reactive ...