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DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
(Peer reviewed; Journal article, 2020)The DNA glycosylase Neil2 is a member of the base excision repair (BER) family of enzymes, which are important for repair of oxidative DNA damage. Specifically, Neil2 participates in repair of oxidized bases in single-stranded ... -
DNA Methylation Adds Prognostic Value to Minimal Residual Disease Status in Pediatric T-Cell Acute Lymphoblastic Leukemia
(Peer reviewed; Journal article, 2016)Background. Despite increased knowledge about genetic aberrations in pediatric T-cell acute lymphoblastic leukemia (T-ALL), no clinically feasible treatment-stratifying marker exists at diagnosis. Instead patients are ... -
DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival
(Peer reviewed; Journal article, 2022)Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ... -
DNA methylation profiling for molecular classification of adult diffuse lower-grade gliomas
(Peer reviewed; Journal article, 2021)Background - DNA methylation profiling has facilitated and improved the classification of a wide variety of tumors of the central nervous system. In this study, we investigated the potential utility of DNA methylation ... -
DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome-including in elderly patients
(Peer reviewed; Journal article, 2022)Elderly patients represent a growing proportion of individuals with glioblastoma, who however, are often excluded from clinical trials owing to poor expected prognosis. We aimed at identifying age-related molecular differences ... -
Do Breast Cancer Patients Manage to Participate in an Outdoor, Tailored, Physical Activity Program during Adjuvant Breast Cancer Treatment, Independent of Health and Socio-Demographic Characteristics?
(Peer reviewed; Journal article, 2022)Exercise could reduce the side-effects of adjuvant breast cancer treatment; however, socio-demographic, health, and intervention conditions may affect patients’ adherence to interventions. This study aimed to examine ... -
Do Childhood Boarding School Experiences Predict Health, Well-Being and Disability Pension in Adults? A SAMINOR Study
(Peer reviewed; Journal article, 2020)Indigenous Sámi and Kven minority children in Norway were during the 20th century placed at boarding schools to hasten their adoption of the Norwegian majority language and culture. This is the first population-based study ... -
Do differences in diagnostic criteria for late fetal growth restriction matter?
(Peer reviewed; Journal article, 2023)BACKGROUND Criteria for diagnosis of fetal growth restriction differ widely according to national and international guidelines, and further heterogeneity arises from the use of different biometric and Doppler reference ... -
Do Gastric Signet Ring Cell Carcinomas and ECL‐Cell Neuroendocrine Tumours Have a Common Origin?
(Peer reviewed; Journal article, 2022)Gastric cancer is a heterogenous group of tumours, and a better understanding of the carcinogenesis and cellular origin of the various sub-types could affect prevention and future treatment. Gastric neuroendocrine tumours ... -
Do Norwegians with diabetes have a healthier diet than the general population?
(Journal article; Peer reviewed, 2013)Objective: Review current knowledge about dietary habits among people with diabetes in Norway compared with the general population and nutrient- and food-based dietary recommendations. Method: Baseline dietary data from ... -
Do patients with gastroesophageal reflux disease exhibit compromised bone quality prior to proton pump inhibitor therapy?
(Peer reviewed; Journal article, 2021)Patients with gastroesophageal reflux disease (GERD) are routinely treated with proton pump inhibitors (PPIs), despite many reports of increased fracture risk associated with PPI use. Notably, the skeletal properties in ... -
Do Various Respirator Models Fit the Workers in the Norwegian Smelting Industry?
(Journal article; Peer reviewed, 2019)Background Respirator fit testing is a method to assess if the respirator provides an adequate face seal for the worker. Methods Workers from four Norwegian smelters were invited to participate in the study, and 701 ... -
Does a history of cardiovascular disease or cancer affect mortality after SARS-CoV-2 infection?
(Peer reviewed; Journal article, 2021)BAKGRUNN Hjerte- og karsykdommer og kreft har vært beskrevet som mulige risikofaktorer for død av covid-19. Hensikten med studien er å undersøke om tidligere påvist hjerte- og karsykdom eller kreft har påvirket risiko for ... -
Does caesarean delivery in the first pregnancy increase the risk for adverse outcome in the second? A registry-based cohort study on first and second singleton births in Norway
(Peer reviewed; Journal article, 2020)Objective To explore if newborns in the second pregnancy following a previous caesarean delivery (CD) have higher risk of perinatal mortality or cerebral palsy than newborns in pregnancies following a previous vaginal ... -
Does Change in Physical Activity During the Initial Phase of the COVID-19 Pandemic Predict Psychological Symptoms in Physically Active Adults? A Six-Month Longitudinal Study
(Peer reviewed; Journal article, 2022)Objectives: The current study aimed to investigate if change in physical activity during the initial phase of the COVID-19 pandemic predicted severity of anxiety and depression symptoms 6 months later in physically active ... -
Does diabetes influence the probability of experiencing chronic low back pain? A population-based cohort study: the Nord-Trøndelag Health Study
(Journal article; Peer reviewed, 2019)Objective Low back pain (LBP) is a major problem in modern society and it is important to study possible risk factors for this disorder. People with diabetes are often affected by LBP, but whether diabetes represents a ... -
Does implementation of a standardized pathway of stroke care affect functional outcome after stroke?
(Journal article; Peer reviewed, 2022) -
Does occupational therapy delay or reduce the proportion of patients that receives thumb carpometacarpal joint surgery? A multicentre randomised controlled trial
(Peer reviewed; Journal article, 2019)Objectives: To evaluate whether occupational therapy, provided in the period between referral and surgical consultation, might delay or reduce the need of surgery in thumb carpometacarpal joint (CMCJ) osteoarthritis and ... -
Does preoperative health-related quality of life predict survival in high-grade glioma patients? – a prospective study
(Peer reviewed; Journal article, 2019)Purpose: To explore if preoperative patient-reported health-related quality of life (HRQoL) provides additional prognostic value as a supplement to other preoperatively known clinical factors in patients with high-grade ... -
Does regular antenatal exercise promote exclusive breastfeeding during the first 3 months of life? Secondary analyses of a randomized controlled trial
(Peer reviewed; Journal article, 2023)Introduction: Exclusive breastfeeding (EBF) and antenatal exercise are independently associated with positive short- and long-term health effects for women and their children. The aims of the study were to investigate ...