• Trajectory of cardiac troponin T following moderate-to-severe COVID-19 and the association with cardiac abnormalities 

      Øvrebotten, Tarjei; Mecinaj, Albulena; Stavem, Knut; Ghanima, Waleed; Brønstad, Eivind; Durheim, Michael Thomas; Lerum, Tøri Vigeland; Josefsen, Tony Andre; Grimsmo, Jostein; Heck, Siri Lagethon; Omland, Torbjørn; Ingul, Charlotte Ingeborg Björk; Einvik, Gunnar; Myhre, Peder Langeland (Journal article; Peer reviewed, 2024)
      Background COVID-19 has been associated with cardiac troponin T (cTnT) elevations and changes in cardiac structure and function, but the link between cardiac dysfunction and high-sensitive cardiac troponin T (hs-cTnT) in ...
    • Trajectory of health-related quality of life during the last year of life in patients with advanced non-small–cell lung cancer 

      Kristensen, Are Korsnes; Grønberg, Bjørn Henning; Fløtten, Øystein; Kaasa, Stein; Solheim, Tora S (Peer reviewed; Journal article, 2022)
      Background The aims of this study were to assess the trajectory of health-related quality of life (HRQOL) during the last year of life in patients with advanced non-small–cell lung cancer (NSCLC) and to explore when and ...
    • Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease 

      Zheng, Jie; Zhang, Yuemiao; Rasheed, Humaira; Walker, Venexia M.; Sugawara, Yuka; Li, Jiachen; Leng, Yue; Elsworth, Benjamin; Wootton, Robyn E.; Fang, Si; Yang, Qian; Burgess, Stephen; Haycock, Philip C.; Borges, Maria Carolina; Carnegie, Rebecca; Cho, Yoonsu; Howell, Amy; Robinson, Jamie; Thomas, Laurent; Brumpton, Ben Michael; Hveem, Kristian; Hallan, Stein; Franceschini, Nora; Morris, Andrew P.; Köttgen, Anna; Pattaro, Cristian; Wuttke, Matthias; Yamamoto, Masayuki; Kashihara, Naoki; Akiyama, Masato; Kanai, Masahiro; Matsuda, Koichi; Kamatani, Yoichiro; Okada, Yukinori; Walters, Robin; Millwood, Iona Y.; Chen, Zhengming; Smith, George Davey; Barbour, Sean; Yu, Canqing; Åsvold, Bjørn Olav; Zhang, Hong; Gaunt, Tom R. (Peer reviewed; Journal article, 2021)
      Background: This study was to systematically test whether previously reported risk factors for chronic kidney disease (CKD) are causally related to CKD in European and East Asian ancestries using Mendelian randomization. ...
    • Trans-fatty acids and survival in renal transplantation 

      Chandra, Anupam; Svensson, My Hanna Sofia; Åsberg, Anders; Schmidt, Erik Berg; Bjerve, Kristian S; Jenssen, Trond Geir; Hartmann, Anders; Ueland, Thor; Eide, Ivar Anders (Journal article; Peer reviewed, 2018)
      Objective High consumption of trans-fatty acids (TFAs) is associated with increased mortality. Design and methods Observational cohort study of 1.988 Norwegian renal transplant recipients with a median follow-up time ...
    • Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas 

      Cobo, Isidoro; Martinelli, Paola; Flández, Marta; Bakiri, Latifa; Zhang, Mingfeng; Carrillo-de-Santa-Pau, Enrique; Jia, Jinping; Lobo, Víctor J. Sánchez-Arévalo; Megías, Diego; Felipe, Irene; del Pozo, Natalia; Millán, Irene; Thommesen, Liv; Bruland, Torunn; Olson, Sara H.; Smith, Jill; Schoonjans, Kristina; Bamlet, William R.; Petersen, Gloria M.; Malats, Núria; Amundadóttir, Laufey T.; Wagner, Erwin F.; Real, Francisco X. (Journal article; Peer reviewed, 2018)
      Chronic inflammation increases the risk of developing one of several types of cancer. Inflammatory responses are currently thought to be controlled by mechanisms that rely on transcriptional networks that are distinct from ...
    • Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease 

      Escudero-hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Munch, Andreas (Peer reviewed; Journal article, 2021)
      Background and aims: The pathophysiology of the inflammatory bowel disease collagenous colitis (CC) is poorly described. Our aim was to use RNA sequencing of mucosal samples from patients with active CC, CC in remission, ...
    • Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project 

      Nordeng, Hedvig Marie Egeland; Wegler, Christine; Lindqvist, Annika; Melander, Erik; Magnusson, Mikaela; Gandia, Peggy; Panchaud, Alice; Baranczewski, Pawel; Spigset, Olav (Peer reviewed; Journal article, 2023)
      Data on drug transfer into human breast milk are sparse. This study aimed to quantify concentrations of cetirizine and levocetirizine in breast milk and to estimate drug exposure to infants. Breastfeeding women at least ...
    • Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding 

      Amundsen, Siri; Nordeng, Hedvig; Nordeng, Hedvig Marie Egeland; Fuskevåg, Ole Martin; Nordmo, Elisabet; Nordmo, Elisabet N; Sager, Georg; Spigset, Olav (Peer reviewed; Journal article, 2021)
      Clinical data on the transfer of triptans into human breast milk remain scarce. In a lactation study including 19 breastfeeding women with migraine, we examined the excretion of six different triptans into milk. Following ...
    • Transfusion of red blood cells in coronary surgery: is there an effect on long-term mortality when adjusting for risk factors and postoperative complications? 

      Tran, Long; Greiff, Guri; Pleym, Hilde; Wahba, Alexander; Stenseth, Roar; Videm, Vibeke (Peer reviewed; Journal article, 2017)
      OBJECTIVES The aim of this study was to compare long-term mortality in patients undergoing primary isolated coronary artery bypass grafting who received ≥1 units of red blood cells (RBCs) or no RBCs. We hypothesized that ...
    • Transfusion practice in Central Norway - a regional cohort study in patients suffering from major haemorrhage 

      Carlsen, Marte Irene Skille; Brede, Jostein Rødseth; Medby, Christian; Uleberg, Oddvar (Peer reviewed; Journal article, 2024)
      Background: In patients with major hemorrhage, balanced transfusions and limited crystalloid use is recommended in both civilian and military guidelines. This transfusion strategy is often applied in the non-trauma patient ...
    • Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats 

      Berger, Hester Rijkje; Nyman, Axel Karl Gottfrid; Morken, Tora Sund; Widerøe, Marius (Journal article; Peer reviewed, 2019)
      Melatonin has potential neuroprotective capabilities after neonatal hypoxia-ischemia (HI), but long-term effects have not been investigated. We hypothesized that melatonin treatment directly after HI could protect against ...
    • Transient global amnesia: 7 Tesla MRI reveals more hippocampal lesions with diffusion restriction compared to 1.5 and 3 Tesla MRI 

      Unsgård, Runa Geirmundsdatter; Doan, Thanh Pierre; Nordlid, Knut; Kvistad, Kjell Arne; Goa, Pål Erik; Berntsen, Erik Magnus (Journal article; Peer reviewed, 2022)
    • Transient ischemic attack or migraine with aura? 

      Alstadhaug, Karl Bjørnar; Tronvik, Erling Andreas; Aamodt, Anne Hege (Peer reviewed; Journal article, 2023)
      Migraine or migraine-like symptoms can contribute to a delayed stroke diagnosis. However, migraine with aura is a common stroke mimic and often the basis for acute thrombolytic therapy. It is probably also the reason why ...
    • Transitioning patients with juvenile idiopathic arthritis to adult care: the Nordic experience 

      Mikola, Katriina; Rebane, Katariina; Arnstad, Ellen Dalen; Berntson, Lillemor; Fasth, Anders; Glerup, Mia; Herlin, Troels; Kautiainen, Hannu; Nielsen, Susan; Nordal, Ellen Berit; Peltoniemi, Suvi; Rygg, Marite; Rypdal, Veronika; Zak, Marek; Aalto, Kristiina (Peer reviewed; Journal article, 2022)
      Background With juvenile idiopathic arthritis (JIA), there are several protocols and practices used worldwide for the transition from paediatric to adult care. In this study, we examined the transferral rates and disease ...
    • Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action 

      Manchia, Mirko; Vieta, Eduard; Smeland, Olav Bjerkehagen; Altimus, Cara; Bechdolf, Andreas; Bellivier, Frank; Bergink, Veerle; Fagiolini, Andrea; Geddes, John R.; Hajek, Tomas; Henry, Chantal; Kupka, Ralph; Lagerberg, Trine Vik; Licht, Rasmus W.; Martinez-Cengotitabengoa, Monica; Morken, Gunnar; Nielsen, René E.; Pinto, Ana Gonzalez; Reif, Andreas; Rietschel, Marcella; Ritter, Philipp; Schulze, Thomas G.; Scott, Janine Linda; Severus, Emanuel; Yildiz, Aysegul; Kessing, Lars Vedel; Bauer, Michael; Goodwin, Guy M.; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2020)
      Bipolar disorder (BD) is a major healthcare and socio-economic challenge. Despite its substantial burden on society, the research activity in BD is much smaller than its economic impact appears to demand. There is a consensus ...
    • Transposition of the apophysis of the greater trochanter for reconstruction of the femoral head after septic hip arthritis in children : 4 children followed for more than 15 years 

      Benum, Pål (Journal article; Peer reviewed, 2011)
      Background and purpose Total necrosis of the femoral head after infection in children during their first months of life gives a dislocated hip with severe leg shortening. A new femoral head can be achieved with subtrochanteric ...
    • The trauma system and the patient - A national, regional and individual perspective 

      Uleberg, Oddvar (Peer reviewed; Journal article, 2019)
      Morbidity and mortality following traumatic injuries constitute a substantial global health challenge. This thesis aimed to describe the current challenges of trauma on a national, regional and individual level. Study 1 ...
    • Traumefokusert kognitiv atferdsterapi for barn og ungdom med PTSD og kompleks PTSD 

      Eidhammer, Sandra Ekelund; Jahr, Håkon Larsen; Blix, Ines; Jensen, Tine Kristin (Peer reviewed; Journal article, 2019)
      Many youth develop complex symptoms after traumatic events. To capture this the ICD-11 has recently added complex posttraumatic stress disorder (CPTSD) as a sibling condition to PTSD. CPTSD includes the three PTSD clusters ...
    • Travel time and perinatal mortality after emergency caesarean sections: an evaluation of the 2-hour proximity indicator in Sierra Leone 

      van Duinen, Aalke Johan; Adde, Håvard Askim; Fredin, Hans Ola; Holmer, Hampus; Hagander, Lars; Koroma, Alimamy Philip; Koroma, Michael M.; Leather, Andy; Wibe, Arne; Bolkan, Håkon Angell (Peer reviewed; Journal article, 2020)
      Introduction Longer travel times are associated with increased adverse maternal and perinatal outcomes. Geospatial modelling has been increasingly used to estimate geographic proximity in emergency obstetric care. In this ...
    • Treatment and 30-day mortality after myocardial infarction in prostate cancer patients: A population-based study from Norway 

      Forster, Rachel Bedenis; Kjellstadli, Camilla; Myklebust, Tor Åge; Egeland, Grace M.; Sulo, Gerhard; Bjørge, Tone; Bønaa, Kaare Harald; Juliusson, Pétur Benedikt; Kvåle, Rune (Peer reviewed; Journal article, 2022)
      Introduction: There is limited knowledge about the use of invasive treatment and mortality after acute myocardial infarction (AMI) in prostate cancer (PCa) patients. We therefore wanted to compare rates of invasive treatment ...