Browsing St. Olavs hospital by Title
Now showing items 2273-2292 of 2475
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Thoracic Radiotherapy in Limited-Stage SCLC—a Population-Based Study of Patterns of Care in Norway From 2000 Until 2018
(Peer reviewed; Journal article, 2022)Introduction Twice-daily (BID) thoracic radiotherapy (TRT) of 45 Gy per 30 fractions is recommended for limited-stage (LS) SCLC, but most patients are treated with once-daily (OD) schedules owing to toxicity concerns ... -
Three groups of suspects in police-reported rape cases: First-time suspects, recidivists and unidentified suspects. A comparative study
(Peer reviewed; Journal article, 2019)Background Previous studies show that reported suspects in adult rape cases often have a criminal record, and that many are rape recidivists. Annual numbers of police reported rapes have dramatically increased but the ... -
Three-year mortality in previously hospitalized older patients from rural areas - the importance of co-morbidity and self-reported poor health
(Journal article; Peer reviewed, 2013)Background The risk factors for mortality after hospitalization in older persons are not fully understood. The aim of the present study was to examine the three-year (1,096 days) mortality in previously hospitalized older ... -
Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)
(Peer reviewed; Journal article, 2023)Purpose Thrombocytopenia (platelet count < 150 × 109/L) is common in intensive care unit (ICU) patients and is likely associated with worse outcomes. In this study we present international contemporary data on ... -
Thromboembolic events after high-intensity training duringcisplatin-based chemotherapy for testicular cancer: Casereports and review of the literature
(Peer reviewed; Journal article, 2020)The randomized “Testicular cancer and Aerobic and Strength Training trial” (TAST‐trial) aimed to evaluate the effect of high‐intensity interval training (HIIT) on cardiorespiratory fitness during cisplatin‐based chemotherapy ... -
Thromboembolic Events During Treatment with Cisplatin-based Chemotherapy in Metastatic Testicular Germ-cell Cancer 2000–2014: A Population-based Cohort Study
(Peer reviewed; Journal article, 2021)Background Cisplatin-based chemotherapy (CBCT) in testicular cancer (TC) is associated with elevated venous thromboembolism (VTE) risk, but trials evaluating the safety and efficacy of thromboprophylaxis are lacking. ... -
Thrombosis and bleedings in a cohort of cancer patients treated with apixaban for venous thromboembolism
(Peer reviewed; Journal article, 2020)Introduction: The direct oral anti-coagulants (DOAC) edoxaban and rivaroxaban are suggested treatment alternatives for cancer-associated venous thromboembolism (VTE) together with low molecular-weight heparins. New studies ... -
Thyroid function, pernicious anemia and erythropoiesis: a two-sample Mendelian randomization study
(Peer reviewed; Journal article, 2022)Autoimmune thyroid disease (AITD) and pernicious anemia (PA) often coexist, but the directionality is unknown. In a two-sample Mendelian randomization (MR) analysis, using summary statistics from large genome-wide association ... -
Thyroid hypofunction in aging testicular cancer survivors
(Peer reviewed; Journal article, 2021)Purpose Thyroid hypofunction is a late effect observed in several groups of cancer survivors, but has to date not been evaluated in-depth in testicular cancer survivors (TCSs). We investigated the prevalence of thyroid ... -
Thyroid Status During Pregnancy in Women With Polycystic Ovary Syndrome and the Effect of Metformin
(Peer reviewed; Journal article, 2022)Objective: Polycystic ovary syndrome (PCOS) and hypothyroidism are related conditions, and both are associated with adverse pregnancy outcomes. Knowledge is lacking about the complex interaction between thyroid status and ... -
Time to classify tumours of the stomach and the kidneys according to cell of origin
(Peer reviewed; Journal article, 2021)Abstract: Malignant tumours are traditionally classified according to their organ of origin and whether they are of epithelial (carcinomas) or mesenchymal (sarcomas) origin. By histological appearance the site of origin ... -
Time to diagnosis in young onset alzheimer's disease: A population-based study from central Norway
(Peer reviewed; Journal article, 2021)Background: Young onset dementia is associated with a longer time to diagnosis compared to late onset dementia. Earlier publications have indicated that atypical presentation is a key contributing factor to the diagnostic ... -
Time-dependent effects on circulating cytokines in patients with LADA: A decrease in IL-1ra and IL-1 beta is associated with progressive disease
(Peer reviewed; Journal article, 2022)Background Cytokines and chemokines participate in autoimmune processes at cellular targets which include insulin-producing beta cells. To which extent such participation is reflected in the circulation has not been ... -
Time-dependent effects on circulating cytokines in patients with LADA: A decrease in IL1-ra and IL-1 beta is associated with progressive disease
(Peer reviewed; Journal article, 2022)Background - Cytokines and chemokines participate in autoimmune processes at cellular targets which include insulin-producing beta cells. To which extent such participation is reflected in the circulation has not been ... -
Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity: A randomized controlled trial
(Peer reviewed; Journal article, 2022)Summary Diet modification and exercise training are primary lifestyle strategies for obesity management, but poor adherence rates limit their effectiveness. Time-restricted eating (TRE) and high-intensity interval training ... -
Timing of severe toxicity from chemotherapy in patients with lung cancer
(Journal article; Peer reviewed, 2020)Background/Aim: The aim of this study was to investigate the timing of severe toxicity in lung cancer patients receiving chemotherapy. Patients and Methods: Patients with advanced non-small cell lung cancer or limited ... -
Tinder use and romantic relationship formations: A large-scale longitudinal sStudy
(Peer reviewed; Journal article, 2020)The current paper aims to investigate if Tinder use predicts romantic relationship formation 1 year later and to identify demographic, personality, mental health, and substance use covariates in the relationship between ... -
TIRAP/Mal Positively Regulates TLR8‐Mediated Signaling via IRF5 in Human Cells
(Peer reviewed; Journal article, 2022)Toll-like receptor 8 (TLR8) recognizes single-stranded RNA of viral and bacterial origin as well as mediates the secretion of pro-inflammatory cytokines and type I interferons by human monocytes and macrophages. TLR8, as ... -
Tissue microstructure is linked to MRI parameters and metabolite levels in prostate cancer
(Peer reviewed; Journal article, 2016)Introduction: Magnetic resonance imaging (MRI) can portray spatial variations in tumor heterogeneity, architecture, and its microenvironment in a non-destructive way. The objective of this study was to assess the relationship ... -
TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies
(Peer reviewed; Journal article, 2020)Inflammation and oxidative stress at the maternal‐fetal interface characterize the placental dysfunction that underlies the pregnancy disorder preeclampsia. Specialized fetal trophoblasts directly interact with leukocytes ...