Browsing St. Olavs hospital by Title

Now showing items 1812-1831 of 2579

    • Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease 

      Gonzalez-Ortiz, Fernando; Kirsebom, Bjørn-Eivind Seljelid; Contador, José; Tanley, Jordan E.; Selnes, Per; Gisladottir, Berglind; Pålhaugen, Lene; Hemminghyth, Mathilde Suhr; Jarholm, Jonas Alexander; Skogseth, Ragnhild Eide; Bråthen, Geir; Grøndtvedt, Gøril; Bjørnerud, Atle; Tecelao, Sandra; Waterloo, Knut; Aarsland, Dag; Fernández-Lebrero, Aida; García-Escobar, Greta; Navalpotro-Gómez, Irene; Turton, Michael; Hesthamar, Agnes; Kac, Przemyslaw R.; Nilsson, Johanna; Luchsinger, Jose; Hayden, Kathleen M.; Harrison, Peter; Puig-Pijoan, Albert; Zetterberg, Henrik; Hughes, Timothy M.; Suárez-Calvet, Marc; Karikari, Thomas K.; Fladby, Tormod; Blennow, Kaj (Journal article; Peer reviewed, 2024)
      Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates ...

    • Plasma Inflammatory Biomarkers Are Associated With Poststroke Cognitive Impairment: The Nor-COAST Study 

      Sandvig, Heidi Vihovde; Aam, Stina; Alme, Katinka Nordheim; Askim, Torunn; Beyer, Mona K.; Ellekjær, Hanne; Ihle-Hansen, Hege Beathe; Lydersen, Stian; Mollnes, Tom Eirik; Munthe-Kaas, Ragnhild; Næss, Halvor; Saltvedt, Ingvild Tina; Seljeseth, Yngve Müller; Thingstad, Anne Pernille Mæhle; Wethal, Torgeir; Knapskog, Anne Brita (Peer reviewed; Journal article, 2023)
      Background: Inflammation is proposed to be involved in the pathogenesis of poststroke cognitive impairment. The aim of this study was to investigate associations between concentrations of systemic inflammatory biomarkers ...

    • Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study 

      Engh, John; Ueland, Thor; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Wedervang-Resell, Kirsten; Weibell, Melissa; Westlye, Lars Tjelta; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole (Peer reviewed; Journal article, 2021)
      Background Immune dysfunction has been implicated in the pathogenesis of schizophrenia and other nonaffective psychosis (SCZ), bipolar spectrum disorder (BIP) and major depressive disorder (MDD). The cytokines B cell-activating ...

    • Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study 

      Dhar, Indu; Lysne, Vegard; Ulvik, Arve; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Kristine Ringdal; Bjørnestad, Espen Øglænd; Olsen, Thomas; Borsholm, Robert Andre; Laupsa-Borge, Johnny; Ueland, Per Magne; Tell, Grethe Seppola; Berge, Rolf Kristian; Mellgren, Gunnar; Bønaa, Kaare Harald; Nygård, Ottar Kjell (Peer reviewed; Journal article, 2023)
      Background Elevated plasma methylmalonic acid (MMA) is reported in patients with established coronary heart disease (CHD) and is considered a marker of vitamin B12 deficiency. Moreover, MMA-dependent reactions have been ...

    • Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation 

      Skaare, Helga; Svensson, My Hanna Sofia; Jenssen, Trond Geir; Åsberg, Anders; Schmidt, Erik Berg; Chandra, Anupam; Ueland, Thor; Mollnes, Tom Eirik; Hartmann, Anders; Eide, Ivar Anders (Journal article; Peer reviewed, 2018)
      Objective The major n-6 polyunsaturated fatty acids linoleic acid (LA) and arachidonic acid (AA) play a role in inflammation and glucose metabolism, which could affect patient and renal transplant survival. Design and ...

    • Plasticity of hippocampal memories in humans 

      Horner, Aidan J.; Doeller, Christian F. (Journal article; Peer reviewed, 2017)
      The human hippocampus is a brain region that supports episodic and spatial memory. Recent experiments have drawn on animal research and computational modelling to reveal how the unique computations and representations of ...

    • Pleural Empyema Caused by Streptococcus intermedius and Fusobacterium nucleatum: A Distinct Entity of Pleural Infections 

      Dyrhovden, Ruben; Eagan, Tomas Mikal Lind; Fløtten, Øystein; Siljan, William Ward; Leegaard, Truls Michael; Bø, Bjørnar; Fardal, Hilde; Grøvan, Fredrik; Kildahl-Andersen, Arne; Larssen, Kjersti Wik; Tilseth, Rune; Hjetland, Reidar; Løes, Sigbjørn Suk; Lindemark, Frode; Tellevik, Marit Gjerde; Breistein, Rebecca Irene; Kommedal, Øyvind (Peer reviewed; Journal article, 2023)
      Background - Many community-acquired pleural infections are caused by facultative and anaerobic bacteria from the human oral microbiota. The epidemiology, clinical characteristics, pathogenesis, and etiology of such ...

    • Pneumonitis and fibrosis after breast cancer radiotherapy: occurrence and treatment-related predictors 

      Karlsen, Jarle; Tandstad, Torgrim; Sowa, Piotr; Salvesen, Øyvind; Stenehjem, Jo S.; Lundgren, Steinar; Reidunsdatter, Randi Johansen (Peer reviewed; Journal article, 2021)
      Background Radiation pneumonitis (RP) and radiation fibrosis (RF) are common side effects after breast cancer (BC) radiotherapy (RT). However, there is a great variation in the frequency of RP and RF. This study presents ...

    • Polycystic ovary syndrome and extremely preterm birth: A nationwide register-based study 

      Valgeirsdottir, Heiddis; Poromaa, Inger Sundström; Kallak, Theodora Kunovac; Vanky, Eszter; Akhter, Tansim; Roos, Nathalie; Stephansson, Olof; Wikström, Anna-Karin (Peer reviewed; Journal article, 2021)
      Women with polycystic ovary syndrome (PCOS) have increased risk of pregnancy complications, including preterm birth before 37 weeks. However, if this increased risk also includes extremely preterm births (<28 weeks) is ...

    • Polycystic ovary syndrome and pregnancy - From a clinical perspective 

      Vanky, Eszter; Løvvik, Tone Shetelig (Peer reviewed; Journal article, 2020)
      For decades, infertility and metabolic health challenges have been the main concerns for women diagnosed with polycystic ovary syndrome (PCOS). Poorer pregnancy outcomes and obstetric complications have only recently been ...

    • Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy 

      Thomas, Hannah S.; Weiser, Thomas G.; Drake, Thomas M.; Knight, Stephen R.; Fairfield, Cameron; Ademuyiwa, Adesoji O.; Lossius, William J; Havemann, Ingemar; Thorsen, Kenneth; Narvestad, Jon; Søreide, Kjetil; Wold, Trude Beate; Nymo, Linn Såve; Veen, Torhild; Kanani, Arezo; Styles, Kristian; Herikstad, Ragnar; Larsen, Johannes Wiik; Søreide, Jon Arne; Jensen, Elisabeth; Gran, Mads; Aahlin, Eirik Kjus; Gaarder, Christine; Monrad-Hansen, Peter Wiel; Næss, Pål Aksel; Lauzikas, Giedrius; Wiborg, Joachim; Holte, Silje; Augestad, Knut Magne; Banipal, Gurpreet Singh; Monteleone, Michela; Moe, Thomas Tetens; Schultz, Johannes Kurt; Bliksøen, Marte; Aguilera-Arevalo, Maria-Lorena; Alexander, Philip; Al-Saqqa, Sara W.; Borda-Luque, Giuliano; Costas-Chavarri, Ainhoa; Ntirenganya, Faustin; Fitzgerald, J. Edward; Fergusson, Stuart J.; Glasbey, James C.; Ingabire, J.C. Allen; Ismaïl, Lawani; Salem, Hosni Khairy; Kojo, Anyomih Theophilus Teddy; Lapitan, Mari Carmela; Lilford, Richard J.; Mihaljevic, Andre L. (Peer reviewed; Journal article, 2019)
      Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to ...

    • Poor prognosis patients with inoperable locally advanced NSCLC and large tumors benefit from palliative chemoradiotherapy: A subset analysis from a randomized clinical phase III trial 

      Strøm, Hans Henrik; Bremnes, Roy M.; Sundstrøm, Stein Harald; Helbekkmo, Nina; Aasebø, Ulf (Peer reviewed; Journal article, 2014)
      Introduction: Poor prognosis patients with bulky stage III locally advanced non–small-cell lung cancer may not be offered concurrent chemoradiotherapy (CRT). Following a phase III trial concerning the effect of palliative ...

    • Poorer sleep health is associated with altered brain activation during cognitive control processing in healthy adults 

      Smevik, Hanne; Habli, Sarah; Saksvik, Simen Berg; Kliem, Elisabeth; Evensmoen, Hallvard Røe; Conde, Virginia; Petroni, Agustin; Asarnow, Robert F.; Dennis, Emily L.; Eikenes, Live; Kallestad, Håvard; Sand, Trond Halfdan; Thompson, Paul M.; Saksvik-Lehouillier, Ingvild; Håberg, Asta; Olsen, Alexander (Peer reviewed; Journal article, 2023)
      This study investigated how proactive and reactive cognitive control processing in the brain was associated with habitual sleep health. BOLD fMRI data were acquired from 81 healthy adults with normal sleep (41 females, age ...

    • A population-based study of caesarean section in women with juvenile idiopathic arthritis 

      Skorpen, Anna Carina G.; Lydersen, Stian; Salvesen, Kjell Åsmund Blix; Wallenius, Marianne (Peer reviewed; Journal article, 2023)
      Objectives: The literature on delivery methods in women with JIA is limited. Active inflammation is a risk factor for caesarean section (CS) in other arthritic diseases. A CS entails a higher risk for complications than ...

    • Possible strategies for use of artificial intelligence in screen-reading of mammograms, based on retrospective data from 122,969 screening examinations 

      Larsen, Marthe; Aglen, Camilla Flåt; Hoff, Solveig Roth; Lund-Hanssen, Håkon; Hofvind, Solveig Sand-Hanssen (Peer reviewed; Journal article, 2022)
      Objectives Artificial intelligence (AI) has shown promising results when used on retrospective data from mammographic screening. However, few studies have explored the possible consequences of different strategies for ...

    • Post mortem tissue distribution of quetiapine in forensic autopsies 

      Breivik, Håvard; Frost, Joachim; Løkken, Trine Nordgård; Slørdal, Lars (Peer reviewed; Journal article, 2020)
      The antipsychotic drug quetiapine is widely used, and increasingly prescribed off-label. Furthermore, quetiapine use has been linked to increased mortality rates, most likely due to a range of cardiovascular and metabolic ...

    • Post-concussion symptoms three months after mild-to-moderate TBI: characteristics of sick-listed patients referred to specialized treatment and consequences of intracranial injury 

      Fure, Silje Christine Reistad; Howe, Emilie; Spjelkavik, Øystein; Røe, Cecilie; Rike, Per-Ola; Olsen, Alexander; Ponsford, Jennie; Andelic, Nada; Løvstad, Marianne (Journal article; Peer reviewed, 2021)
      Objective: To present pre-injury, injury-related, work-related and post-injury characteristics, and to compare patients with and without traumatic intracranial abnormalities, in a treatment-seeking sample with persistent ...

    • Post-discharge suicide among high-risk psychiatric inpatients: Risk factors and warnings signs 

      Prestmo, Astrid; Høyen, Karina Sagmo; Vaaler, Arne Einar; Torgersen, Terje; Kvithyld, Tuva Prestmo; Cohen, Lisa Janet; Drange, Ole Kristian (Peer reviewed; Journal article, 2023)
      Background The present study explored the predictive value of a novel suicide risk assessment with regard to suicide deaths within three years of discharge from an acute inpatient unit. The contributions of the different ...

    • Post-Fracture Risk Assessment: Target The Centrally Sited Fractures First! A Sub-Study of NoFRACT 

      Borgen, Tove Tveitan; Bjørnerem, Åshild; Solberg, Lene Bergendal; Andreasen, Camilla; Brunborg, Cathrine; Stenbro, May-Britt; Hübschle, Lars Michael; Froholdt, Anne; Figved, Wender; Apalset, Ellen Margrete; Gjertsen, Jan-Erik; Basso, Trude; Lund, Ida; Hansen, Ann Kristin; Stutzer, Jens-Meinhard; Omsland, Tone Kristin; Nordsletten, Lars; Frihagen, Frede Jon; Eriksen, Erik Fink (Peer reviewed; Journal article, 2019)
      The location of osteoporotic fragility fractures adds crucial information to post-fracture risk estimation. Triaging patients according tofracture site for secondary fracture prevention can therefore be of interest to ...

    • Post-stroke Cognitive Impairment—Impact of Follow-Up Time and Stroke Subtype on Severity and Cognitive Profile: The Nor-COAST Study 

      Aam, Stina; Einstad, Marte Stine; Munthe-Kaas, Ragnhild; Lydersen, Stian; Ihle-Hansen, Hege; Knapskog, Anne Brita; Ellekjær, Hanne; Seljeseth, Yngve Müller; Saltvedt, Ingvild (Peer reviewed; Journal article, 2020)
      Background: Post-stroke cognitive impairment (PSCI) is common, but evidence of cognitive symptom profiles, course over time, and pathogenesis is scarce. We investigated the significance of time and etiologic stroke subtype ...