Browsing St. Olavs hospital by Title
Now showing items 1226-1245 of 2460
-
Intranasal analgesia for acute moderate to severe pain in children – a systematic review and meta-analysis
(Peer reviewed; Journal article, 2023)Background Children in acute pain often receive inadequate pain relief, partly from difficulties administering injectable analgesics. A rapid-acting, intranasal (IN) analgesic may be an alternative to other parenteral ... -
Intraoperative 3D ultrasound-guided resection of diffuse low-grade gliomas: radiological and clinical results
(Peer reviewed; Journal article, 2019)OBJECTIVE Extent of resection (EOR) and residual tumor volume are linked to prognosis in low-grade glioma (LGG) and there are various methods for facilitating safe maximal resection in such patients. In this prospective ... -
Intraoperative risk factors for peritumoral infarctions following glioma surgery
(Peer reviewed; Journal article, 2022)Background Surgical intraoperative risk factors for peritumoral infarctions are not much studied. In the present study, we explore the possible association between intraoperative factors and infarctions diagnosed from ... -
Intraoperatively local infiltration anesthesia in hemiarthroplasty patients reduces the needs of opioids: a randomized, double-blind, placebo-controlled trial with 96 patients in a fast-track hip fracture setting
(Peer reviewed; Journal article, 2022)Background and purpose — Local infiltration analgesia (LIA) is commonly used as a component in multimodal analgesia. Pain management directed towards hip fracture patients operated on with hemiarthroplasty is often based ... -
Intrapartum ultrasound assessment of cervical dilatation and its value in detecting active labor
(Peer reviewed; Journal article, 2018)Introduction We aimed to examine the agreement between ultrasound and digital vaginal examination in assessing cervical dilatation in an African population and to assess the value of ultrasound in detecting active ... -
Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
(Peer reviewed; Journal article, 2023)Colorectal and ovarian cancers frequently develop peritoneal metastases with few treatment options. Intraperitoneal chemotherapy has shown promising therapeutic effects, but is limited by rapid drug clearance and systemic ... -
Intraperitoneal insulin administration in pigs: Effect on circulating insulin and glucose levels
(Peer reviewed; Journal article, 2021)Introduction The effect of intraperitoneal insulin infusion has limited evidence in the literature. Therefore, the aim of the study was to investigate the pharmacokinetics and pharmacodynamics of different intraperitoneal ... -
Intratumor DNA methylation heterogeneity in glioblastoma: Implications for DNA methylation-based classification
(Peer reviewed; Journal article, 2019)Background. A feature of glioblastoma (GBM) is cellular and molecular heterogeneity, both within and between tumors. This variability causes a risk for sampling bias and potential tumor escape from future targeted therapy. ... -
Intravenous Iron Treatment in the Prevention of Iron Deficiency and Anaemia After Roux-en-Y Gastric Bypass
(Peer reviewed; Journal article, 2020)Background Iron absorption is disturbed after Roux-en-Y gastric bypass (RYGB) and iron deficiency with or without anaemia affects almost half of all patients. Intravenous iron is an option when per oral iron is insufficient ... -
Intraventricular Vector Flow Imaging with Blood Speckle Tracking in Adults: Feasibility, Normal Physiology and Mechanisms in Healthy Volunteers
(Peer reviewed; Journal article, 2021)This study examines the feasibility of blood speckle tracking for vector flow imaging in healthy adults and describes the physiologic flow pattern and vortex formation in relation to the wall motion in the left ventricle. ... -
Introducing fairness in Norwegian air ambulance base location planning
(Peer reviewed; Journal article, 2021)Background A primary task of the Norwegian helicopter emergency medical services (HEMS) is to provide advanced medical care to the critical ill and injured outside of hospitals. Where HEMS bases are located, directly ... -
The introduction of a regional Norwegian HEMS coordinator: an assessment of the effects on response times, geographical service areas and severity scores
(Peer reviewed; Journal article, 2022)Background Due to unwanted delays and suboptimal resource control of helicopter emergency medical services (HEMS), regional HEMS coordinators have recently been introduced in Norway. This may represent an unnecessary ... -
Investigating a Potential Causal Relationship Between Maternal Blood Pressure During Pregnancy and Future Offspring Cardiometabolic Health
(Peer reviewed; Journal article, 2021)Observational epidemiological studies have reported that higher maternal blood pressure (BP) during pregnancy is associated with increased future risk of offspring cardiometabolic disease. However, it is unclear whether ... -
Investigating causal relations between sleep traits and risk of breast cancer in women: Mendelian randomisation study
(Peer reviewed; Journal article, 2019)Objective To examine whether sleep traits have a causal effect on risk of breast cancer. Design Mendelian randomisation study. Setting UK Biobank prospective cohort study and Breast Cancer Association Consortium ... -
Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study
(Peer reviewed; Journal article, 2021)Background Sedentary behaviour is associated with disease, but the molecular mechanisms are not understood. Valid biomarkers with predictive and explanatory properties are required. Therefore, we have investigated traditional ... -
Investigating optimal β-cell-preserving treatment in latent autoimmune diabetes in adults: Results from a 21-month randomized trial
(Peer reviewed; Journal article, 2019)Aims To compare outcomes of glucagon‐stimulated C‐peptide tests (GSCTs) in people with latent autoimmune diabetes in adults (LADA) after a 21‐month intervention with either insulin or the dipeptidyl peptidase‐4 inhibitor ... -
Investigating survival, quality of life and cognition in PROton versus photon therapy for IDH- mutated diffuse grade 2 and 3 GLIOmas (PRO-GLIO): a randomised controlled trial in Norway and Sweden
(Peer reviewed; Journal article, 2023)Abstract Introduction The use of proton therapy increases globally despite a lack of randomised controlled trials demonstrating its efficacy and safety. Proton therapy enables sparing of non-neoplastic tissue from ... -
Investigating the causal interplay between sleep traits and risk of acute myocardial infarction: a Mendelian randomization study
(Peer reviewed; Journal article, 2023)Background Few studies have investigated the joint effects of sleep traits on the risk of acute myocardial infarction (AMI). No previous study has used factorial Mendelian randomization (MR) which may reduce confounding, ... -
Investigating the effect of sex and ketosis on weight-loss-induced changes in appetite
(Peer reviewed; Journal article, 2019)Background Diet-induced weight loss (WL) is usually accompanied by increased appetite, a response that seems to be absent when ketogenic diets are used. It remains unknown if sex modulates the appetite suppressant effect ... -
Investigation to identify individual socioeconomic and health determinants of suicidal ideation using responses to a cross-sectional, community-based public health survey
(Peer reviewed; Journal article, 2021)Abstract Objectives To address a gap in knowledge by simultaneously assessing a broad spectrum of individual socioeconomic and potential health determinants of suicidal ideation (SI) using validated measures in a large UK ...