Optical dip probes for near-infrared spectroscopic glucose sensing in peritoneal fluid

Abstract

The aim of this study was to investigate the possibilities of using near infrared spectroscopic measurements to detect and quantify glucose concentration in peritoneal fluid samples. This was done with a fibre dip probe in samples obtained from patients at St. Olavs Hospital. The measurements was done by transflection in small sample volumes, hoping to shed some light the eventual future application of this method in an implantable glucose sensor. The acquired spectra were analysed with the use of the multivariate calibration techniques PCA and PLSR. Particular useful wavelengths were identified by MWPLSR.