Browsing Institutt for sirkulasjon og bildediagnostikk by Title
Now showing items 1097-1116 of 1866
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Metabolic profiling of colorectal cancer organoids: A comparison between high-resolution magic angle spinning magnetic resonance spectroscopy and solution nuclear magnetic resonance spectroscopy of polar extracts
(Peer reviewed; Journal article, 2022)Patient-derived cancer cells cultured in vitro are a cornerstone of cancer metabolism research. More recently, the introduction of organoids has provided the research community with a more versatile model system. Physiological ... -
Metabolic re-wiring of isogenic breast epithelial cell lines following epithelial to mesenchymal transition
(Journal article; Peer reviewed, 2017)Epithelial to mesenchymal transition (EMT) has implications in tumor progression and metastasis. Metabolic alterations have been described in cancer development but studies focused on the metabolic re-wiring that takes ... -
Metabolic reprogramming supports the invasive phenotype in malignant melanoma
(Journal article; Peer reviewed, 2015)Invasiveness is a hallmark of aggressive cancer like malignant melanoma, and factors involved in acquisition or maintenance of an invasive phenotype are attractive targets for therapy. We investigated melanoma phenotype ... -
Metabolic response to everolimus in patient-derived triple negative breast cancer xenografts
(Journal article; Peer reviewed, 2017)Patients with triple-negative breast cancer (TNBC) are unresponsive to endocrine and anti-HER2 pharmacotherapy, limiting their therapeutic options to chemotherapy. TNBC is frequently associated with abnormalities in the ... -
Metabolite and lipoprotein responses and prediction of weight gain during breast cancer treatment
(Journal article; Peer reviewed, 2018)Background Breast cancer treatment has metabolic side effects, potentially affecting risk of cardiovascular disease (CVD) and recurrence. We aimed to compare alterations in serum metabolites and lipoproteins during treatment ... -
Metabolomic biomarkers in serum and urine in women with preeclampsia
(Journal article, 2014)Objective To explore the potential of magnetic resonance (MR) metabolomics for study of preeclampsia, for improved phenotyping and elucidating potential clues to etiology and pathogenesis. Methods Urine and serum ... -
Metabolomic Biomarkers of Preeclampsia: An NMR Protocol Development and Pilot Study
(Master thesis, 2012)Preeclampsia is a serious complication of pregnancy, which presents risk to both the expectant mother and to the fetus. It affects 3-8% of pregnancies, resolves only upon delivery, and is a major cause of preterm birth. ... -
Metabolomics identifies placental dysfunction and confirms Flt-1 (FMS-like tyrosine kinase receptor 1) biomarker specificity
(Journal article; Peer reviewed, 2019)Clinical end-stage parameters define the pregnancy disorders preeclampsia and fetal growth restriction while classification of the underlying placental dysfunction is missing and urgently needed. Flt-1 (FMS-like tyrosine ... -
Metacognitions are associated with subjective memory problems in individuals on sick leave due to chronic fatigue
(Peer reviewed; Journal article, 2016)Background: Subjective cognitive impairments are frequent, but poorly understood in patients with chronic fatigue. We hypothesized that maladaptive metacognitive beliefs at baseline were associated with baseline subjective ... -
Metacognitive Beliefs as Predictors of Return to Work After Intensive Return-to-Work Rehabilitation in Patients With Chronic Pain, Chronic Fatigue and Common Psychological Disorders: Results From a Prospective Trial
(Peer reviewed; Journal article, 2020)Background: Metacognitions are associated with work status, but no research has examined to what extent metacognitions before treatment and change in metacognitions following treatment predict return to work (RTW) ... -
Metal Artifact Reduction for Total Hip Replacement in MRI
(Master thesis, 2019)Projektets baggrund: Philips 1.5 T-scanneren gennemgik en hardware-og softwareopgradering. Under denne proces var nogle af protokollerne ikke blevet opgraderet. Den gyldne standard pseudotumor hofte protokol bestod af 4 ... -
Method for Designing Semantic Annotation of Sepsis Signs in Clinical Text
(Chapter, 2023)Annotated clinical text corpora are essential for machine learning studies that model and predict care processes and disease progression. However, few studies describe the necessary experimental design of the annotation ... -
MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas
(Peer reviewed; Journal article, 2020)O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment ... -
MicroRNA as biomarkers in colorectal cancer
(Master thesis, 2016)Colorectal cancer (CRC) is one of the worlds leading causes of cancer-related deaths in both men and women. Nearly 1.4 million new cases were reported in 2012 and over half of the cases ended in death. High mortality rates ... -
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
(Peer reviewed; Journal article, 2019)Matrix metalloproteinases (MMP) are important for cardiac remodeling. Recently, microRNA (miR)-451a has been found to inhibit the expression of both MMP-2 and MMP-9 in human malignancies, but its role in cardiomyocytes has ... -
Microscale nuclear magnetic resonance gradient chip
(Peer reviewed; Journal article, 2022)We propose a design, micro fabrication process, and nuclear magnetic resonance (NMR) based evaluation, of a magnetic field gradient chip. The uni-axial linear z-gradient coil design was computed by a stream-function method, ... -
Midterm Outcomes for Endovascular Repair of Thoraco-Abdominal Aortic Aneurysms
(Journal article; Peer reviewed, 2022) -
Migraine and endothelial function: The HUNT3 Study.
(Journal article; Peer reviewed, 2016)Background: Reduced endothelial function is associated with elevated risk of cardiovascular disease, but evidence on the association between migraine and endothelial function is conflicting. The aim of this population-based ... -
Minimally invasive beat-by-beat monitoring of cardiac power in normal hearts and during acute ventricular dysfunction
(Journal article; Peer reviewed, 2016)Cardiac power, the product of aortic flow and blood pressure, appears to be a fundamental cardiovascular parameter. The simplified version named cardiac power output (CPO), calculated as the product of cardiac output (CO) ... -
Minor Myocardial Scars in Association with Cardiopulmonary Function after COVID-19
(Peer reviewed; Journal article, 2023)Background: Myocardial scars detected by cardiovascular magnetic resonance (CMR) imaging after COVID-19 have caused concerns regarding potential long-term cardiovascular consequences. Objective: The objective of this study ...