Blar i Institutt for klinisk og molekylær medisin på emneord "VDP::Medical disciplines: 700"
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A Dual Role of Autophagy in Disease Prevention and Drug Resistance
(Doctoral thesis at NTNU;2015:310, Doctoral thesis, 2015)Aging is associated with various diseases, such as neurodegenerative diseases. However, individual risk of developing these age-related diseases clearly varies due to differences in both genetic and environmental factors. ... -
A Toll-like receptor 7/8 ligand secreted by a myeloma cell line induces primary bone marrow stromal cells to produce survival promoting cytokines
(Master thesis, 2015)Multiple myeloma (MM) is a cancer of plasma cells, which accumulate in the bone marrow (BM). The BM milieu provides MM cells with survival and proliferation signals. Toll-like receptors (TLRs) are immune receptors that ... -
An Attempt to Elucidate the Genes Encoding the Surface Exposed Proteins R3, Z1 and Z2 in Two Strains of Streptococcus agalactiae from Zimbabwe
(Master thesis, 2014)Surface exposed proteins of Streptococcus agalactiae (GBS) may be used in serotyping and may have a potential role as vaccine candidates. The proteins R3 and the recently discovered Z1 and Z2 were found to be important ... -
Analysis of protein-nucleic acids interactions involved in handling of genotoxic stress
(Doctoral theses at NTNU;2016:323, Doctoral thesis, 2016) -
Androgen receptor expression in breast cancer subtypes
(Master thesis, 2016)Background The androgen receptor (AR) is frequently expressed in breast cancer, and associated with good prognosis in ER-positive breast cancers. Due to its high prevalence, AR is also a possible target for therapeutic ... -
Antimicrobial peptides targeting the beta-clamp
(Doctoral theses at NTNU;2023:94, Doctoral thesis, 2023) -
Are mirror movements associated with bimanual hand function among children with unilateral spastic cerebral palsy?
(Master thesis, 2016)Children and adolescents with unilateral spastic cerebral palsy (USCP) may experience mirror movements (MM). The amount of MM may indicate differences in the organization of the cortico-spinal motor tracts, which may ... -
Aspects of assessment, classification and treatment of cancer pain
(Doctoral theses at NTNU;2020:31, Doctoral thesis, 2020) -
Atherosclerotic and obesity-associated inflammation : focus on cholesterol crystals, complement and coagulation
(Master thesis, 2015)Atherosclerosis is a chronic inflammatory disease of the arterial wall, and a leading cause of death worldwide. An emerging role for the complement system in the pathogenesis of atherosclerosis is demonstrated by the ... -
Autophagy as a Survival Mechanism or a Cause of Disease
(Doctoral thesis at NTNU;2016:52, Doctoral thesis, 2016)Proper turnover of cellular components is crucial for all cells. If damaged or excessive content in the cell is not removed at a sufficient pace, normal cell functions may be compromised. The same may occur if the ... -
Beauty and the Beast: The Multifaceted Potential of Mesenchymal Stem Cells in Bone Health and Disease
(Doctoral thesis at NTNU;2015:171, Doctoral thesis, 2015)Mesenkymale stamceller: Biologi og terapeutisk potensiale: Skjelettet er det som holder kroppen vår oppe, beskytter organene våre og det er samtidig en viktig kilde for kalsium og fosfater. Humant beinvev består av en ... -
The burden of rheumatoid arthritis - physical fitness, function, and mortality
(Doctoral theses at NTNU;2023:243, Doctoral thesis, 2023)Patients with rheumatoid arthritis (RA) have higher mortality rates than the general population as well as lower cardiorespiratory fitness. They also have an increased risk of myocardial infarction of similar magnitudes ... -
Caesarean Sections in Sierra Leone An Evaluation in the Light of the Lancet Global Surgery Indicators
(Doctoral theses at NTNU;2021:402, Doctoral thesis, 2021)Background: Two third of the world’s population does not have adequate access to timely safe and affordable surgical services. The Lancet Commission on Global Surgery has defined a framework with six indicators and targets ... -
Can ultrasound predict labor outcome in operative vaginal deliveries?
(Doctoral theses at NTNU;2020:183, Doctoral thesis, 2020) -
Cancer pain assessment, classification and patient reported outcomes in the evaluation of treatment effect
(Doctoral theses at NTNU;2016:328, Doctoral thesis, 2016)Pain is common in patients with cancer and it has a strong impact on quality of life. Despite the development of guidelines, cancer pain treatment is suboptimal. This is often due to lack of efficient, standardized and ... -
Cancer pain – clinical studies on prevalence and treatment with nasal fentanyl
(Doctoral thesis at NTNU;2016:81, Doctoral thesis, 2016)Summary in English: Pain is one of the most feared symptoms among cancer patients. Studies show that about 50% of all cancer patients experience pain and these numbers are increasing for patients with advanced disease. ... -
Causal role of human bocavirus 1 in respiratory tract infections in children
(Doctoral theses at NTNU;2016:257, Doctoral thesis, 2016)Norsk sammendrag: Humant bocavirus 1 og luftveisinfeksjoner hos barn Humant bocavirus 1 (HBoV1) ble oppdaget i 2005 i luftveisprøver fra barn med luftveisinfeksjon. Det tilhører familien Parvoviridae, og var det første ... -
Challenges in implementing circulating tumor DNA analyses in lung cancer research
(Doctoral theses at NTNU;2023:327, Doctoral thesis, 2023)Lung cancer is the leading cause of cancer-related deaths worldwide, including Norway. This study focused on non-small cell lung cancer (NSCLC), the most common subtype, and aimed to enhance the classification of NSCLC ... -
Checkpoint Inhibition in Multiple Myeloma
(Doctoral theses at NTNU;2019:107, Doctoral thesis, 2019) -
Claims for compensation from gynecological patients - what can we learn?
(Doctoral theses at NTNU;2021:327, Doctoral thesis, 2021)