Blar i Institutt for klinisk og molekylær medisin på tidsskrift "EMBO Journal"

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    • Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity 

      Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B; Brech, A; Latz, Eicke; Espevik, Terje (Journal article; Peer reviewed, 2006)
      Immune responses are initiated when molecules of microbial origin are sensed by the Toll‐like receptors (TLRs). We now report the identification of essential molecular components for the trafficking of the lipopolysaccharide ...

    • LRRK2 to the rescue of damaged endomembranes 

      Radulovic, Maja; Stenmark, Harald Alfred (Peer reviewed; Journal article, 2020)
      Mutations in several genes encoding for lysosomal proteins are involved in Parkinson's disease (PD). In this issue, Herbst et al (2020) show that PD-related leucine-rich repeat kinase 2 (LRRK2) is activated in response to ...

    • Sealing holes in cellular membranes 

      Zhen, Yan; Radulovic, Maja; Vietri, Marina; Stenmark, Harald (Peer reviewed; Journal article, 2021)
      The compartmentalization of eukaryotic cells, which is essential for their viability and functions, is ensured by single or double bilayer membranes that separate the cell from the exterior and form boundaries between the ...