Browsing Institutt for klinisk og molekylær medisin by Subject "VDP::Medisinske Fag: 700"
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Associations between the FTO rs9939609 genotypes and insulin sensitivity, glucose tolerance, energy metabolism, appetite hormones, and diet in patients with severe obesity
(Doctoral theses at NTNU;2022:398, Doctoral thesis, 2022) -
Blood flow calculated in the uterine arteries based on the PixelFlux technique
(Master thesis, 2017)Introduction: We aimed to compare two Doppler methods which calculate blood flow in the uterine arteries. We also aimed to explore associations between blood flow with birthweight and with fetal weight-gain/day from ... -
Cognitive function during disease progression in a rat model of Alzheimer’s disease - Effect of a single bout of exhaustive aerobic exercise
(Master thesis, 2018)Alzheimer’s disease (AD), the most prevalent form of dementia, is a devastating neurodegenerative disorder affecting over 35 million people worldwide. As age is the main risk factor for AD, and no current treatment options ... -
Computational Analysis of DNA Methylation and Gene Expression Patterns in Prostate Cancer
(Master thesis, 2018)DNA methylation is an important contributor for prostate cancer development and progression. It has been studied experimentally for years, but, lately, high-throughput technologies are able to produce genome-wide DNA ... -
Coping strategies for community singing among older adults living with hearing impairment: A mixed methods study
(Master thesis, 2017)Bakgrunn Evnen til å kommunisere er avgjørende for menneskelig samspill. Hele 62% av nordmenn over 65 år har en hørselshemning som påvirker kommunikasjonsevnen. Med en aldrende befolkning vil dette bli et økende problem ... -
Diagnostikk av Mycoplasma genitalium: evaluering av optimalt tidspunkt for urinprøvetaking : kvantitativ PCR-undersøkelse av Mycoplasma genitalium i urinprøver tatt med økende tidsintervall
(Master thesis, 2016)Formålet med studien: Det finnes per i dag ingen internasjonal konsensus vedrørende anbefalt tidsintervall fra siste miksjon til urinprøve bør tas for optimal deteksjon av Mycoplasma genitalium. De nyeste europeiske ... -
Differentiation of women into low- and high-risk for complications during labor
(Master thesis, 2017)Objective: To ensure that women receive adequate care during labor, women are classified according to risk, low- or high-risk. Classification is carried out on admission to the maternity unit, and risk is continuously ... -
Effects of cPLA2α inhibition in the MDAMB-468 cell model system for basal-like breast cancer and/or triple negative breast cancer
(Master thesis, 2016)Basal-like breast cancer (BLBC) is a highly aggressive breast cancer sub-type and represents ~15% of all breast cancers. BLBC are often associated with early age of onset, early relapse and poor overall survival in contrast ... -
Energimetabolisme i skjelettmuskelceller fra smertepasienter : myokiner, smerteopplevelse og effekt av trimetylamin N-oksid
(Master thesis, 2016)Background: Dysfunctional energy metabolism in skeletal muscle is associated with obesity, metabolic syndrome, type 2 diabetes (T2DM) and cardiovascular diseases (CVD). Detrimental changes in energy metabolism are result ... -
Evaluation of a surgical trainee logbook system in Sierra Leone
(Master thesis, 2017)Background Task-sharing is an increasingly used tool to improve surgical capacity in low-income countries. Within task-sharing training programs surgical logbooks are commonly applied for monitoring and evaluation of the ... -
Expression of PPARγ in inflammatory bowel disease: a role in regulating colonic inflammation
(Master thesis, 2017)Background: Inflammatory bowel disease (IBD) is a collective term for the two entities, ulcerative colitis (UC) and Crohn’s disease (CD). They are both characterized by a relapsing inflammation causing destruction of the ... -
Expression of Transforming growth factor beta in Breast Cancer Subtypes
(Master thesis, 2017)Background: Normally, transforming growth factor beta (TGF-b) functions as a tumorsuppressor. But, during carcinogenesis, malignant cells become insensitive to TGF-b´s growth inhibitory abilities, and the traits of TGF-b ... -
Forekomst av komplikasjoner ved gjenopprettelse av normal tarmkontinuitet etter avlastende stomi ved St. Olavs Hospital
(Master thesis, 2016)Bakgrunn: Å gjenopprette normal tarmkontinuitet etter avlastende stomier er beheftet med komplikasjoner. I denne studien ønsket vi å sammenligne resultatene ved St. Olavs hospital fra 2012 til 2015 med andre materialer, ... -
Forekomst av rabdomyolyse hos friske forsøkspersoner etter en hard treningsøkt
(Master thesis, 2017)Bakgrunn Forekomsten av treningsinsdusert rabdomyolyse har vært økende de siste årene. Formålet med studien var å undersøke hvor stor andel av friske forsøkspersoner som utviklet stigning i kreatinkinase (CK) og kreatinin, ... -
Frequency of risk factors and long-term complications in a female population with previously diagnosed diabetes mellitus in rural Nepal
(Master thesis, 2017)Background: Diabetes mellitus (DM) is a noncommunicable disease causing 1.5 million deaths annually in 2012. Its global prevalence is growing dramatically, projecting to 10.4% of the adult population in 2040. Almost 75% ... -
Førekomst og erfaringar med legemiddelinteraksjonar ved sjukehusapotek i Helse Midt-Norge
(Master thesis, 2016)Bakgrunn Apotek er ein viktig arena for å fange opp og handtere legemiddelinteraksjonar. Vurdering og handtering av interaksjonar utgjer ein stor del av farmasøytane sin arbeidskvardag, og kan til tider vere svært ... -
Gynecological complaints and management of women subjected to female genital mutilation - A descriptive study among women attending a university hospital in Norway
(Master thesis, 2017)Abstract Background Female genital mutilation (FGM) is a harmful traditional practice comprising procedures involving partial or total removal of external female genitalia and/or narrowing of the vaginal orifice for ... -
Heterogeneity within the 66cl4 cell line from the 4T1 model of metastatic breast cancer
(Master thesis, 2018)Breast cancer is one of the most common form of cancer among women globally and metastasis is the primary cause of death in breast cancer patients. In the past decades it has been increasingly known that tumors are ... -
IL-32 and multiple myeloma bone disease
(Master thesis, 2016)Multiple myeloma is a malignancy of plasma cells characterized by multiple tumors in the bone marrow and progressive osteolytic bone disease. The bone lesions are caused by increased bone resorption by osteoclasts and ... -
Immunomodulatory effects of iron oxide nanoparticles in two human biological model systems
(Doctoral theses at NTNU;2017:368, Doctoral thesis, 2017)