Blar i Institutt for bioteknologi og matvitenskap på tittel
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Mechanistic basis of substrate–O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study
(Peer reviewed; Journal article, 2020)Lytic polysaccharide monooxygenases (LPMOs) have a unique ability to activate molecular oxygen for subsequent oxidative cleavage of glycosidic bonds. To provide insight into the mode of action of these industrially important ... -
Meeting Report: 1st International Functional Metagenomics Workshop May 7-8, 2012, St. Jacobs, Ontario, Canada
(Journal article; Peer reviewed, 2013)This report summarizes the events of the 1st International Functional Metagenomics Workshop. The workshop was held on May 7 and 8, 2012, in St. Jacobs, Ontario, Canada and was focused on building an international functional ... -
Melbillelarver (Tenebrio molitor) som kjøtterstatter. Produktutvikling, forbrukeraksept og holdninger
(Bachelor thesis, 2023)Den økende verdensbefolkningen gjør det nødvendig å utforske bærekraftige proteinkilder for å møte økende matbehov. Insekter er en del av kostholdet til mennesker i enkelte deler av verden, likevel har ikke vestlige ... -
Mesophilic Aeromonas spp. isolated from ready-to-eat seafood: Insight into antimicrobial resistance, virulence factors, and growth kinetics in food
(Doctoral theses at NTNU;2023:279, Doctoral thesis, 2023)With the current trend of consuming fresh, natural, and convenient food, ready-to-eat (RTE) seafood, such as sushi, sashimi, or cold-smoked fish products, has gained popularity. Increased consumption of RTE seafood poses ... -
Metabolic analyses of stress response in a non-cancerous cell line exposed to Cisplatin and a novel PCNA-interacting motif
(Master thesis, 2013)Several proteins involved in DNA-damage repair have been found to interact with the proliferating cell nuclear antigen (PCNA) through a novel PCNA-interacting motif, an amino acid sequence called the AlkB homologue 2 ... -
Metabolic and Lipidomic Profling of Docosahexaenoic acid Producing Aurantiochytrium sp. T66
(Master thesis, 2020)Fiskeoljeproduksjonen er hovedkilden til omega-3 fettsyrer i fôr til lakseoppdrett, og tilførselen av fiskeolje har blitt en begrenset ressurs. Samtidig forventes det at den marine akvakulturen vil fortsette å vokse, og ... -
Metabolic Changes in Response to Cell Cycle Synchronization and Treatment with Chemotherapeutic Drugs: Targeted and Non-Targeted Mass Spectrometric Analysis of Human Cell Lines
(Master thesis, 2013)In life sciences, the rise of the omics-era the recent decades has greatly contributed to increased understanding of biological systems. The latest addition to the omics group is metabolomics ? the science that aims at ... -
Metabolic engineering of B. methanolicus for production of 3-hydroxypropionic acid
(Master thesis, 2020)Bacillus methanolicus er en Gram-positiv, stavformet, metylotrof og termofil bakterie som kan vokse på metanol som eneste karbonkilde, noe som gjør den til en attraktiv vertsorganisme for mikrobiell produksjon av diverse ... -
Metabolic engineering of Bacillus methanolicus for production of recombinant proteins and acetoin from methanol
(Doctoral theses at NTNU;2020:339, Doctoral thesis, 2020)The use of methanol as a carbon source for industrial biotechnology is a tantalizing prospect. Methanol is highly abundant, and has a long history of efficient, large-scale production. It can be produced abiotically from ... -
Metabolic Engineering of Bacillus methanolicus MGA3 for Production of Acetoin
(Master thesis, 2018)Being a pure, inexpensive, non-food chemical that can be sustainably produced, methanol has attracted great interest as a carbon feedstock for microbial production of commodity/specialty chemicals. In this thesis, ... -
Metabolic engineering of Bacillus methanolicus MGA3 for the production of enantiopure 2,3-butanediol
(Master thesis, 2023)Metanol som råstoff for mikrobiell produksjon av verdiøkende kjemikalier har flere fordeler i forhold til kostnad og bærekraft. I denne masteroppgaven var målet å lage rekombinante Bacillus methanolicus MGA3 stammer for ... -
Metabolic engineering of Bacillus methanolicus towards methanol-based lactam production
(Master thesis, 2020)Industriell bioteknologi er en av de største og mest fremtidsrettede feltene som har vokst fram i det 21ste århundret. Det har mange applikasjoner innen viktige industrielle områder som medisin, planteproduksjon, og ... -
Metabolic engineering of Corynebacterium glutamicum for de novo production of 3-hydroxycadaverine
(Peer reviewed; Journal article, 2022)Functionalization of amino acids and their derivatives opens up the possibility to produce novel compounds with additional functional groups, which can expand their application spectra. Hydroxylation of polyamide building ... -
Metabolic engineering of industrially relevant strains for the production of riboflavin from sustainable feedstocks
(Doctoral theses at NTNU;2024:95, Doctoral thesis, 2024)There is an increasing demand for agricultural land and other resources necessary to feed an expanding world population. This has led to a growing interest in using sustainable feedstocks to produce value-added compounds ... -
Metabolic Engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol
(Peer reviewed; Journal article, 2023)The growing need of next generation feedstocks for biotechnology spurs an intensification of research on the utilization of methanol as carbon and energy source for biotechnological processes. In this paper, we introduced ... -
Metabolic engineering to understand and control productionof l-glutamate from methanol by the methylotrophic thermotolerant bacterium Bacillus methanolicus
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:337, Doctoral thesis, 2013)The production of L-glutamate and L-lysine together excides 3.5 million tons annually and are the most important amino acids in production volume. Their production is based on fermentation processes with the bacterium ... -
Metabolic memory underlying minimal residual disease in breast cancer
(Peer reviewed; Journal article, 2021)Tumor relapse from treatment-resistant cells (minimal residual disease, MRD) underlies most breast cancer-related deaths. Yet, the molecular characteristics defining their malignancy have largely remained elusive. Here, ... -
Metabolic network layout using biochemical coordinates
(Master thesis, 2022)De kjemiske egenskapene til molekyler er preget av numeriske verdier kjent som molekylære deskriptorer og beregnes fra molekylære representasjoner i kjeminformatiske verktøy. Ulike molekylære deskriptorer brukes for å ... -
Metabolic Profiling of Cisplatin and ATX-101 Induced Stress-responses in the Bladder Cancer Cell Line T24
(Master thesis, 2016)Proliferating cell nuclear antigen (PCNA) is a protein central in many cellular processes through its numerous protein interaction partners. Recently, it has been shown that several proteins involved in stress related ... -
Metabolic Profiling of Escherichia coli BL21 During Recombinant Protein Production with Varying Expression Vector Characteristics
(Master thesis, 2022)The production of recombinant proteins usingmicrobial cell factories such as Escherichia coli (E. coli) is both a high value industry and a growing area of interest for the field of metabolomics. While historical industrial ...