dc.contributor.author | Haugen, Anders Johan Smedman | |
dc.contributor.author | Hallan, Stein | |
dc.contributor.author | Langberg, Nina Elisabeth Borthen | |
dc.contributor.author | Dahle, Dag Olav | |
dc.contributor.author | Pihlstrøm, Hege | |
dc.contributor.author | Birkeland, Kåre I. | |
dc.contributor.author | Reisæter, Anna Varberg | |
dc.contributor.author | Midtvedt, Karsten | |
dc.contributor.author | Hartmann, Anders | |
dc.contributor.author | Holdaas, Hallvard | |
dc.contributor.author | Mjøen, Geir | |
dc.date.accessioned | 2022-11-28T13:43:58Z | |
dc.date.available | 2022-11-28T13:43:58Z | |
dc.date.created | 2020-10-14T14:00:06Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Transplant International. 2020, 33 (5), 536-543. | en_US |
dc.identifier.issn | 0934-0874 | |
dc.identifier.uri | https://hdl.handle.net/11250/3034517 | |
dc.description.abstract | Kidney donors may be at increased risk of end-stage renal disease and premature mortality. Elevated blood pressure after donation may contribute to the increased risks. In this cohort study, we have assessed long-term risk for the development of hypertension in kidney donors compared to a control group potentially eligible as donors. Follow-up data were obtained from previous living kidney donors. A healthy control group with baseline assessment from similar time periods as the donor nephrectomies was selected. Hypertension was defined as blood pressure >140/90, use of blood pressure medication, or established diagnosis of hypertension. Stratified logistic regression was used to estimate risk of hypertension at follow-up, adjusted for systolic blood pressure at baseline, age at follow-up, time since donation/baseline, gender, smoking at baseline, and BMI at baseline. A total of 368 donors (36%) had hypertension at follow-up, and 241 of these (23%) were using blood pressure medication. In adjusted stratified logistic regression analyses, odds ratio for hypertension was significantly increased (1.25, 95% confidence interval 1.12–1.39, P < 0.001) in donors compared with controls. Kidney donors appear to be at increased long-term risk for hypertension compared with healthy controls. This finding supports regular follow-up of blood pressure in kidney donors. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Increased long-term risk for hypertension in kidney donors – a retrospective cohort study | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | acceptedVersion | en_US |
dc.source.pagenumber | 536-543 | en_US |
dc.source.volume | 33 | en_US |
dc.source.journal | Transplant International | en_US |
dc.source.issue | 5 | en_US |
dc.identifier.doi | 10.1111/tri.13576 | |
dc.identifier.cristin | 1839579 | |
cristin.ispublished | true | |
cristin.fulltext | postprint | |
cristin.qualitycode | 1 | |