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Working Memory Training in Amnestic and Non-amnestic Patients With Mild Cognitive Impairment: Preliminary Findings From Genotype Variants on Training Effects

dc.contributor.authorHernes, Susanne Miriam Sørensen
dc.contributor.authorFlak, Marianne Møretrø
dc.contributor.authorLøhaugen, Gro Christine Christensen
dc.contributor.authorSkranes, Jon Sverre
dc.contributor.authorHol, Haakon Ramsland
dc.contributor.authorMadsen, Bengt-Ove
dc.contributor.authorKnapskog, Anne Brita
dc.contributor.authorEngvig, Andreas
dc.contributor.authorPripp, Are Hugo
dc.contributor.authorUlstein, Ingun
dc.contributor.authorLona, Trine Eli.b.
dc.contributor.authorZhang, Xin
dc.contributor.authorChang, Linda
dc.date.accessioned2022-10-19T07:17:14Z
dc.date.available2022-10-19T07:17:14Z
dc.date.created2021-04-08T12:46:08Z
dc.date.issued2021
dc.identifier.issn1663-4365
dc.identifier.urihttps://hdl.handle.net/11250/3026893
dc.description.abstractWorking memory training (WMT) effects may be modulated by mild cognitive impairment (MCI) subtypes, and variations in APOE-epsilon (APOE-ε) and LMX1A genotypes. Sixty-one individuals (41 men/20 women, mean age 66 years) diagnosed with MCI (31 amnestic/30 non-amnestic) and genotyped for APOE-ε and LMX1A completed 4 weeks/20-25 sessions of WMT. Cognitive functions were assessed before, 4 weeks and 16 weeks after WMT. Except for Processing Speed, the non-amnestic MCI group (naMCI) outperformed the amnestic MCI (aMCI) group in all cognitive domains across all time-points. At 4 weeks, working memory function improved in both groups (pen_US
dc.language.isoengen_US
dc.publisherFrontiersen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleWorking Memory Training in Amnestic and Non-amnestic Patients With Mild Cognitive Impairment: Preliminary Findings From Genotype Variants on Training Effectsen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.volume13en_US
dc.source.journalFrontiers in Aging Neuroscienceen_US
dc.identifier.doi10.3389/fnagi.2021.624253
dc.identifier.cristin1902953
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal