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dc.contributor.authorBruland, Torunn
dc.contributor.authorØstvik, Ann Elisabet
dc.contributor.authorSandvik, Arne Kristian
dc.contributor.authorHansen, Marianne Dore
dc.date.accessioned2022-04-26T08:44:41Z
dc.date.available2022-04-26T08:44:41Z
dc.date.created2021-10-16T14:08:54Z
dc.date.issued2021
dc.identifier.issn1661-6596
dc.identifier.urihttps://hdl.handle.net/11250/2992736
dc.description.abstractUlcerative colitis is characterized by relapsing and remitting colonic mucosal inflammation. During the early stages of viral infection, innate immune defenses are activated, leading to the rapid release of cytokines and the subsequent initiation of downstream responses including inflammation. Previously, intestinal viruses were thought to be either detrimental or neutral to the host. However, persisting viruses may have a role as resident commensals and confer protective immunity during inflammation. On the other hand, the dysregulation of gut mucosal immune responses to viruses can trigger excessive, pathogenic inflammation. The purpose of this review is to discuss virus-induced innate immune responses that are at play in ulcerative colitis.en_US
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleHost-Viral Interactions in the Pathogenesis of Ulcerative Colitisen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.source.volume22en_US
dc.source.journalInternational Journal of Molecular Sciencesen_US
dc.source.issue19en_US
dc.identifier.doi10.3390/ijms221910851
dc.identifier.cristin1946404
dc.relation.projectSamarbeidsorganet mellom Helse Midt-Norge og NTNU: 90285400en_US
dc.relation.projectSamarbeidsorganet mellom Helse Midt-Norge og NTNU: 90660400en_US
dc.relation.projectSamarbeidsorganet mellom Helse Midt-Norge og NTNU: 90660401en_US
dc.relation.projectSamarbeidsorganet mellom Helse Midt-Norge og NTNU: 90545800en_US
dc.relation.projectSamarbeidsorganet mellom Helse Midt-Norge og NTNU: 90546600en_US
dc.relation.projectNorges forskningsråd: 223255en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal