Polycystic ovary syndrome and pregnancy - From a clinical perspective

Abstract

For decades, infertility and metabolic health challenges have been the main concerns for women diagnosed with polycystic ovary syndrome (PCOS). Poorer pregnancy outcomes and obstetric complications have only recently been recognized as concerns for women with PCOS. Women diagnosed with PCOS are more often overweight and obese, and the prevalence of pregnancy complications in PCOS is influenced by several co-factors such as body mass index, co-morbidities, and ethnicity. The most frequently reported pregnancy complications in PCOS are gestational diabetes, miscarriage and preterm delivery, hypertension, and preeclampsia. This narrative review focuses on existing evidence and clinical practice for prepregnancy screening, antenatal care, and postpartum follow-up of women with PCOS. We also briefly review treatment options, neonatal outcomes, and breastfeeding. Our aim is to increase awareness about obstetric challenges in PCOS.