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    • Gene expression studies and targeted metabolomics reveal disturbed serine, methionine, and tyrosine metabolism in early hypertensive nephrosclerosis 

      Øvrehus, Marius Altern; Bruheim, Per; Ju, Wenjun; Zelnick, Leila R.; Langlo, Knut Asbjørn Rise; Sharma, Kumar; de Boer, Ian H.; Hallan, Stein (Journal article; Peer reviewed, 2019)
      Introduction Hypertensive nephrosclerosis is among the leading causes of end-stage renal disease, but its pathophysiology is poorly understood. We wanted to explore early metabolic changes using gene expression and targeted ...

    • Gene mining for proline based signaling proteins in cell wall of Arabidopsis thaliana 

      Ihsan, Muhammad Z.; Ahmad, Samina Jam Nazeer; Shah, Zahid Hussain; Rehman, Hafiz M.; Aslam, Zubair; Ahuja, Ishita; Bones, Atle M.; Ahmad, Jam N. (Journal article; Peer reviewed, 2017)
      The cell wall (CW) as a first line of defense against biotic and abiotic stresses is of primary importance in plant biology. The proteins associated with cell walls play a significant role in determining a plant's ...

    • Gene Network Inference and Biochemical Assessment Delineates GPCR Pathways and CREB Targets in Small Intestinal Neuroendocrine Neoplasia 

      Drozdov, Ignat; Svejda, Bernhard; Gustafsson, Björn; Mane, S; Pfragner, Roswitha; Kidd, Mark; Modlin, Irvin M (Journal article; Peer reviewed, 2011)
      Small intestinal (SI) neuroendocrine tumors (NET) are increasing in incidence, however little is known about their biology. High throughput techniques such as inference of gene regulatory networks from microarray experiments ...

    • Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort 

      Tripathi, Sushil; Christie, KR; Balakrishnan, Ravin; Huntley, R; Hill, DP; Thommesen, Liv; Blake, JA; Kuiper, Martin; Lægreid, Astrid (Journal article; Peer reviewed, 2013)
      Transcription factors control which information in a genome becomes transcribed to produce RNAs that function in the biological systems of cells and organisms. Reliable and comprehensive information about transcription ...

    • The Gene Ontology resource: enriching a GOld mine 

      Carbon, Seth J.; Douglass, Eric; Good, Benjamin M; Unni, Deepak R; Harris, Nomi L.; Mungall, Christopher J.; Basu, Siddartha; Chisholm, Rex L.; Dodson, Robert J.; Hartline, Eric; Fey, Petra; Thomas, Paul D.; Albou, Laurent-Philippe; Ebert, Dustin; Kesling, Michael J; Mi, Huaiyu; Muruganujan, Anushya; Huang, Xiaosong; Mushayahama, Tremayne; LaBonte, Sandra A.; Siegele, Deborah A.; Antonazzo, Giulia; Attrill, Helen; Brown, Nick H.; Garapati, Phani; Marygold, Steven J.; Trovisco, Vitor; dos Santos, Gil; Falls, Kathleen; Tabone, Christopher; Zhou, Pinglei; Goodman, Joshua L.; Strelets, Victor B.; Thurmond, Jim; Garmiri, Penelope; Ishtiaq, Rizwan; Rodríguez-López, Milagros; Acencio, Marcio Luis; Kuiper, Martin; Lægreid, Astrid; Logie, Colin; Lovering, Ruth C.; Kramarz, Barbara; Saverimuttu, Shirin C.C.; Pinheiro, Sandra M.; Gunn, Heather; Su, Renzhi; Thurlow, Katherine E.; Chibucos, Marcus; Giglio, Michelle; Nadendla, Suvarna; Munro, James; Jackson, Rebecca; Duesbury, Margaret J.; del-Toro, Noemi; Meldal, Birgit H.M.; Paneerselvam, Kalpana; Perfetto, Livia; Porras, Pablo; Orchard, Sandra; Shrivastava, Anjali (Peer reviewed; Journal article, 2021)
      The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium ...

    • Gene regulation knowledge commons: community action takes care of DNA binding transcription factors 

      Tripathi, Sushil; Vercruysse, Steven; Chawla, Konika; Christie, Karen R.; Blake, Judith A; Huntley, Rachael P.; Orchard, Sandra; Hermjakob, Henning; Thommesen, Liv; Lægreid, Astrid; Kuiper, Martin (Journal article; Peer reviewed, 2016)
      A large gap remains between the amount of knowledge in scientific literature and the fraction that gets curated into standardized databases, despite many curation initiatives. Yet the availability of comprehensive knowledge ...

    • The gene regulation knowledge commons: the action area of GREEKC 

      Kuiper, Martin; Bonello, Joseph; Fernández-Breis, Jesualdo Tomás; Bucher, Philipp; Futschik, Matthias E; Gaudet, Pascale; Kulakovskiy, Ivan V.; Licata, Luana; Logie, Colin; Lovering, Ruth C.; Makeev, Vsevolod J; Orchard, Sandra; Panni, Simona; Perfetto, Livia; Sant, David; Schulz, Stefan M.; Vercruysse, Steven; Zerbino, Daniel; Lægreid, Astrid (Peer reviewed; Journal article, 2022)
      As computational modeling becomes more essential to analyze and understand biological regulatory mechanisms, governance of the many databases and knowledge bases that support this domain is crucial to guarantee reliability ...

    • Gene regulation of carbon fixation, storage, and utilization in the diatom phaeodactylum tricornutum acclimated to light/dark cycles 

      Chauton, Matilde Skogen; Winge, Per; Brembu, Tore; Vadstein, Olav; Bones, Atle M. (Journal article; Peer reviewed, 2013)
      The regulation of carbon metabolism in the diatom Phaeodactylum tricornutum at the cell, metabolite, and gene expression levels in exponential fed-batch cultures is reported. Transcriptional profiles and cell chemistry ...

    • Gene signatures ESC, MYC and ERG-fusion are early markers of a potentially dangerous subtype of prostate cancer 

      Rye, Morten Beck; Bertilsson, Helena; Drabløs, Finn; Angelsen, Anders; Bathen, Tone Frost; Tessem, May-Britt (Journal article; Peer reviewed, 2014)
      Background Good prognostic tools for predicting disease progression in early stage prostate cancer (PCa) are still missing. Detection of molecular subtypes, for instance by using microarray gene technology, can give new ...

    • General and abdominal obesity and incident asthma in adults: the HUNT study 

      Brumpton, Ben Michael; Langhammer, Arnulf; Romundstad, Pål Richard; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2013)
      Measures of body mass index (BMI) and waist circumference define general obesity and abdominal obesity respectively. While high BMI has been established as a risk factor for asthma in adults, waist circumference has seldom ...

    • General and alcohol-related social media use and mental health: A large-sample longitudinal study 

      Erevik, Eilin K.; Pallesen, Ståle; Vedaa, Øystein; Andreassen, Cecilie Schou; Dhir, Amandeep; Torsheim, Torbjørn (Peer reviewed; Journal article, 2020)
      The current study aimed to investigate if general and alcohol-related social media use predicts symptoms of depression and anxiety. Students in Bergen, Norway, participated in a Web-based survey during fall 2015 (T1) and ...

    • A General and Effective Method for Wall and Protrusion Separation from Facade Point Clouds 

      Cai, Shangshu; Zhang, Shuhang; Zhang, Wuming; Fan, Hongchao; Shao, Jie; Yan, Guangjian; Yu, Sisi; Li, Aiguang; Zhou, Guoqing (Peer reviewed; Journal article, 2023)
      As a critical prerequisite for semantic facade reconstruction, accurately separating wall and protrusion points from facade point clouds is required. The performance of traditional separation methods is severely limited ...

    • General boundary conditions for quasiclassical theory of superconductivity in the diffusive limit: Application to strongly spin-polarized systems 

      Eschrig, Matthias; Cottet, Audrey; Belzig, W; Linder, Jacob (Journal article; Peer reviewed, 2015)
      Boundary conditions in quasiclassical theory of superconductivity are of crucial importance for describing proximity effects in heterostructures between different materials. Although they have been derived for the ballistic ...

    • General bulk-viscous solutions and estimates of bulk viscosity in the cosmic fluid 

      Normann, Ben David; Brevik, Iver Håkon (Journal article; Peer reviewed, 2016)
      We derive a general formalism for bulk viscous solutions of the energy-conservation equation for ρ(a,ζ) ρ(a,ζ) , both for a single-component and a multicomponent fluid in the Friedmann universe. For our purposes, these ...

    • The General Flow Proneness Scale: Aspects of Reliability and Validity of a New 13-Item Scale Assessing Flow 

      Elnes, Magdalena; Sigmundsson, Hermundur (Peer reviewed; Journal article, 2023)
      In this article, we report the development and validation of a new measure for flow proneness. The General Flow Proneness Scale is a quantitative measure which is simple to administer, and is context independent. Test-retest ...

    • A general framework for stock dynamics of populations and built and natural environments 

      Lauinger, Dirk; Billy, Romain Guillaume; Vasquez, Felipe; Mueller, Daniel Beat (Peer reviewed; Journal article, 2021)
      Sustainable development involves a responsible management of the interactions between humans and their built and natural environment. From a physical perspective, the interactions can be characterized as stocks and flows ...

    • General Health, Vitality, and Social Function After Sinus Surgery in Chronic Rhinosinusitis 

      Nilsen, Ann Helen; Helvik, Anne-Sofie; Thorstensen, Wenche Moe; Salvesen, Øyvind; Bugten, Vegard (Journal article; Peer reviewed, 2019)
      Objectives Chronic rhinosinusitis (CRS) has an impact on health‐related quality of life (HRQOL). The objective of this study was to examine generic and disease‐specific HRQOL and symptoms in CRS patients with (CRSwNP) ...

    • General heat transfer correlations for supercritical carbon dioxide heated in vertical tubes for upward and downward flows 

      Ye, Zuliang; Zendehboudi, Alireza; Hafner, Armin; Cao, Feng (Peer reviewed; Journal article, 2022)
      Supercritical CO2 is a promising working fluid for many industrial applications. To improve the performances of relevant components and systems, the prediction of the heat transfer of supercritical CO2 is an important ...

    • General movement optimality score and general movements trajectories following early parent-administrated physiotherapy in the neonatal intensive care unit 

      Ustad, Tordis; Fjørtoft, Toril Larsson; Øberg, Gunn Kristin (Peer reviewed; Journal article, 2021)
      Background The Prechtl General Movement Assessment (GMA) is a reliable tool for the functional assessment of the young nervous system. It is based on a global assessment of the quality of infants' movements. In addition, ...

    • General order conditions for stochastic partitioned Runge–Kutta methods 

      Anmarkrud, Sverre; Debrabant, Kristian; Kværnø, Anne (Journal article; Peer reviewed, 2017)
      In this paper stochastic partitioned Runge–Kutta (SPRK) methods are considered. A general order theory for SPRK methods based on stochastic B-series and multicolored, multishaped rooted trees is developed. The theory is ...