Blar i Publikasjoner fra CRIStin - NTNU på tittel

Viser treff 20226-20245 av 37384

    • Loss of glutamate transporter eaat2a leads to aberrant neuronal excitability, recurrent epileptic seizures, and basal hypoactivity 

      Hotz, Adriana L.; Jamali, Ahmed; Rieser, Nicolas N.; Niklaus, Stephanie; Aydin, Ecem; Myren-Svelstad, Sverre; Lalla, Laetitia Noelle Patricia; Jurisch-Yaksi, Nathalie; Yaksi, Emre; Neuhauss, Stephan C.F. (Peer reviewed; Journal article, 2021)
      Astroglial excitatory amino acid transporter 2 (EAAT2, GLT-1, and SLC1A2) regulates the duration and extent of neuronal excitation by removing glutamate from the synaptic cleft. Hence, an impairment in EAAT2 function could ...

    • Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation 

      Rolinski, Milosz; Montaldo, Nicola Pietro; Aksu, Merdane Ezgi; Martin, Sarah Fordyce; Brambilla, Alessandro; Kunath, Nicolas; Johansen, Jostein; Erlandsen, Sten Even; Liabakk, Nina-Beate; Rian, Kristin; Bjørås, Magnar; Sætrom, Pål; van Loon, Barbara (Peer reviewed; Journal article, 2020)
      Alkylating drugs are among the most often used chemotherapeutics. While cancer cells frequently develop resistance to alkylation treatments, detailed understanding of mechanisms that lead to the resistance is limited. Here, ...

    • Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration 

      Felszeghy, Szabolcs; Viiri, Johanna; Paterno, Jussi J.; Hyttinen, Juha M.T.; Koskela, Ali; Chen, Mei; Leinonen, Henri; Tanila, Heikki; Kivinen, Niko; Koistinen, Arto; Toropainen, Elisa; Amadio, Marialaura; Smedowski, Adrian; Reinisalo, Mika; Winiarczyk, Mateusz; Mackiewicz, Jerzy; Mutikainen, Maija; Ruotsalainen, Anna-Kaisa; Kettunen, Mikko; Jokivarsi, Kimmo; Sinha, Debasish; Kinnunen, Kati; Petrovski, Goran; Blasiak, Janusz; Bjørkøy, Geir; Koskelainen, Ari; Skottman, Heli; Urtti, Arto; Salminen, Antero; Kannan, Ram; Ferrington, Deborah A.; Xu, Heping; Levonen, Anna-Liisa; Tavi, Pasi; Kauppinen, Anu; Kaarniranta, Kai (Journal article; Peer reviewed, 2019)
      Age-related macular degeneration (AMD) is a multi-factorial disease that is the leading cause of irreversible and severe vision loss in the developed countries. It has been suggested that the pathogenesis of dry AMD involves ...

    • Loss of statin treatment years during pregnancy and breastfeeding periods in women with familial hypercholesterolemia 

      Klevmoen, Marianne; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Svilaas, Tone; Vesterbekkmo, Elisabeth Kleivhaug; Hovland, Anders; Berge, Christ; van Lennep, Jeanine Roeters; Holven, Kirsten Bjørklund (Peer reviewed; Journal article, 2021)
      Background and aims Women with heterozygous familial hypercholesterolemia (FH) are recommended to initiate statin treatment at the same age as men (from 8 to 10 years of age). However, statins are contraindicated when ...

    • Loss of the arabidopsis protein kinases ANPs affects root cell wall composition, and triggers the cell wall damage syndrome 

      Gigli, Nora; Savatin, Daniel V; Cervone, Felice; Engelsdorf, Timo; De Lorenzo, Giulia (Journal article; Peer reviewed, 2018)
      The Arabidopsis NPK1-related Protein kinases ANP1, ANP2 and ANP3 belong to the MAP kinase kinase kinase (MAPKKK) superfamily and were previously described to be crucial for cytokinesis, elicitor-induced immunity and ...

    • Loss or mislocalization of aquaporin-4 affects diffusion properties and intermediary metabolism in gray matter of mice 

      Pavlin, Tina; Nagelhus, Erlend Arnulf; Brekken, Christian; Eyjolfsson, Elvar M.; Thoren, Anna; Haraldseth, Olav; Sonnewald, Ursula; Ottersen, Ole Petter; Håberg, Asta (Journal article; Peer reviewed, 2017)
      The first aim of this study was to determine how complete or perivascular loss of aquaporin-4 (AQP4) water channels affects membrane permeability for water in the mouse brain grey matter in the steady state. Time-dependent ...

    • Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease 

      Nielsen, Jonas Bille; Rom, Oren; Surakka, Ida; Graham, Sarah E.; Zhou, Wei; Roychowdhury, Tanmoy; Fritsche, Lars; Gagliano Taliun, Sarah; Sidore, Carlo; Liu, Yuhao; Gabrielsen, Maiken Elvestad; Skogholt, Anne Heidi; Wolford, Brooke; Overton, William; Zhao, Ying; Chen, Jin; Zhang, He; Hornsby, Whitney E.; Acheampong, Akua; Grooms, Austen; Schaefer, Amanda; Zajac, Gregory J.M.; Villacorta, Luis; Zhang, Jifeng; Brumpton, Ben Michael; Løset, Mari; Rai, Vivek; Lundegaard, Pia R.; Olesen, Morten S.; Taylor, Kent D.; Palmer, Nicholette D.; Chen, Yii-Der; Choi, Seung Hoan; Lubitz, Steven A.; Ellinor, Patrick T.; Barnes, Kathleen C.; Daya, Michelle; Rafaels, Nicholas; Weiss, Scott T.; Lasky-Su, Jessica; Tracy, Russell P.; Vasan, Ramachandran S.; Cupples, L. Adrienne; Mathias, Rasika A.; Yanek, Lisa R.; Becker, Lewis; Holmen, Oddgeir Lingaas; Åsvold, Bjørn Olav; Willer, Christen; Hveem, Kristian (Peer reviewed; Journal article, 2020)
      Pharmaceutical drugs targeting dyslipidemia and cardiovascular disease (CVD) may increase the risk of fatty liver disease and other metabolic disorders. To identify potential novel CVD drug targets without these adverse ...

    • A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial–temporal regulation of histone arginine methylation in neurodevelopment 

      Lin, Xiaolin; Wang, Wei; Yang, Mingyi; Damseh, Nadirah; Sousa, Mirta; Jacob, Fadi; lång, anna ulrika; Kristiansen, Elise; Pannone, Marco; Kissova, Miroslava; Almaas, Runar; Kusnierczyk, Anna; Siller, Richard; Shahrour, Maher; Al-Ashhab, Motee; Abu-Libdeh, Bassam; Tang, Wannan; Slupphaug, Geir; Elpeleg, Orly; Bøe, Stig Ove; Eide, Lars; Sullivan, Gareth John; Rinholm, Johanne Egge; Song, Hongjun; Ming, Guo-li; van Loon, Barbara; Edvardson, Simon; Ye, Jing; Bjørås, Magnar (Peer reviewed; Journal article, 2023)
      Background Oxidation Resistance 1 (OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, antioxidant ...

    • Lost and found twice: Discussion of an early post-glacial single-edged tanged point from Brodgar on Orkney, Scotland 

      Ballin, Torben Bjarke; Bjerck, Hein Bjartmann (Journal article; Peer reviewed, 2016)
      Over the last few decades it has been shown that Scotland was settled – or at least occasionally visited – during the late Upper Palaeolithic period. The finds include diagnostic artefacts of Hamburgian, Federmesser and ...

    • Lost Futures? Educated Youth Precarity and Protests in the Oromia Region, Ethiopia 

      Abebe, Tatek (Peer reviewed; Journal article, 2020)
      Drawing on ethnographic fieldwork, this article explores the connections between young people's livelihoods, education and visions of the future in Ethiopia. It engages with educated youth's narratives of precarity, ...

    • Lost in motivation: The case of a Norwegian community healthcare project ethical reflection 

      Nilsen, Heidi Rapp; Ringholm, Toril Merete (Journal article; Peer reviewed, 2019)
      Innovations are needed to meet increasing challenges in public healthcare, and type of motivation has been identified as a pivotal factor for the success of an innovation. New public management crowd out the intrinsic ...

    • Lost in motivation? The case of a Norwegian community healthcare project on ethical reflection 

      Nilsen, Heidi Rapp; Ringholm, Toril Merete (Journal article; Peer reviewed, 2019)
      Innovations are needed to meet increasing challenges in public healthcare, and type of motivation has been identified as a pivotal factor for the success of an innovation. New public management crowd out the intrinsic ...

    • Lost in the loop - A qualitative study on patient experiences of care in standardized cancer patient pathways 

      Solberg, Monica; Berg, Geir Vegar; Andreassen, Hege Kristin (Peer reviewed; Journal article, 2023)
      Background: The Norwegian health authorities introduced standardized cancer patient pathways (CPPs) in 2015, aiming to reduce practice variations across hospitals and regions, and improve the continuity, coordination and ...

    • Lost in Translation? Multiple Discursive Strategies and the Interpretation of Sustainability in the Norwegian Salmon Farming Industry 

      Aarset, Bernt; Carson, Siri Granum; Wiig, Heidi; Måren, Inger Elisabeth; Marks, Jessica (Peer reviewed; Journal article, 2020)
      The term ‘sustainability’ is vague and open to interpretation. In this paper we analyze how firms use the term in an effort to make the concept their own, and how it becomes a premise for further decisions, by applying a ...

    • The Lottery Fantasy and Social Mobility in Eighteenth-Century Venetian Literature: Carlo Goldoni, Pietro Chiari, and Giacomo Casanova 

      Haugen, Marius Warholm (Peer reviewed; Journal article, 2022)
      This article examines the lottery fantasy as a cultural figure and literary topic in the works of Carlo Goldoni, Pietro Chiari, and Giacomo Casanova. The lottery fantasy is to be understood as the dream of social ascension ...

    • Louis Vuitton in the bazaar: Negotiating the value of counterfeit goods in Shanghai's Xiangyang market 

      Hansen, Gard Hopsdal; Møller, Henrik Kloppenborg (Journal article; Peer reviewed, 2017)
      Abstract: Much work on counterfeiting takes the perspective of brand holders and focuses on strategies for restricting the infringement of their intellectual property rights (IPR). This article takes a different approach. ...

    • Louise Labé: «Nouvelle Sappho» eller «créature de papier»? 

      Svelstad, Per Esben (Journal article; Peer reviewed, 2012)

    • Louise Labés feministiske epistel: Ein eksklusiv fellesskap 

      Myren-Svelstad, Per Esben (Journal article; Peer reviewed, 2016)
      The French poet Louise Labé (152?–1564) has been portrayed for the last century as an early feminist. But is Labé’s vision of a liberated future only relevant for those who possess the «commodity» of intellectual goods? ...

    • The (love & hate) role of entropy in process metallurgy 

      Tveit, Halvard; Kolbeinsen, Leiv (Journal article, 2019)
      Abstract. Process metallurgy is the basis for the production, refining and recycling of metals and is based on knowledge of transport phenomena, thermodynamics and reaction kinetics, and of their interaction in high ...

    • Love in the Mother Tongue: Per Fokstad’s Philosophy of Education 

      Svendsen, Stine H. Bang (Peer reviewed; Journal article, 2024)