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dc.contributor.authorNilsen, Ann Helen
dc.contributor.authorHelvik, Anne-Sofie
dc.contributor.authorThorstensen, Wenche Moe
dc.contributor.authorSalvesen, Øyvind
dc.contributor.authorBugten, Vegard
dc.identifier.citationLaryngoscope Investigative Otolaryngology. 2019, 4 (5), 476-483.nb_NO
dc.description.abstractObjectives Chronic rhinosinusitis (CRS) has an impact on health‐related quality of life (HRQOL). The objective of this study was to examine generic and disease‐specific HRQOL and symptoms in CRS patients with (CRSwNP) and without (CRSsNP) nasal polyps before and 6 months after sinus surgery, and to identify preoperative patient factors associated with HRQOL outcome in the two groups separately. Methods This prospective, observational study consisted of 220 CRSwNP and 196 CRSsNP patients. Generic and disease‐specific HRQOL were measured using the Short‐Form‐Health‐Survey (SF‐36) and Sino‐Nasal‐Outcome‐Test (SNOT‐20). Symptoms were assessed on a visual analog scale. Results Preoperatively, CRSwNP patients reported worse score in general health (SF‐36), rhinologic subset (SNOT‐20): nasal obstruction, nasal discharge, and altered sense of smell compared to CRSsNP patients, who reported worse score in physical role, bodily pain, ear/face subset, and facial pain. After surgery, generic and disease‐specific HRQOL and symptoms improved in both groups. CRSwNP patients had greater improvement in general health, vitality and social function, nasal obstruction, and altered sense of smell, compared to CRSsNP‐patients. In both groups, higher age, daily smoking, and having had sinus surgery previously were associated with less generic HRQOL improvement, in addition to female sex and allergy in CRSsNP patients. Conclusion The greater improvement in general health, vitality, and social function after surgery may indicate a greater potential for generic HRQOL improvement in CRSwNP patients compared to CRSsNP patients. Female sex and allergy was associated with less improvement of generic HRQOL in the CRSsNP group, but not in the CRSwNP group.nb_NO
dc.publisherWiley Periodicals, Inc. on behalf of The Triological Society.nb_NO
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.titleGeneral Health, Vitality, and Social Function After Sinus Surgery in Chronic Rhinosinusitisnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.source.journalLaryngoscope Investigative Otolaryngologynb_NO
dc.description.localcode© 2019 The Authors. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.nb_NO
cristin.unitnameKlinikk for ØNH, kjeve- og øyesykdommer
cristin.unitnameInstitutt for nevromedisin og bevegelsesvitenskap
cristin.unitnameAllmennmedisinsk forskningsenhet i Trondheim
cristin.unitnameInstitutt for samfunnsmedisin og sykepleie

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Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal