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The retrosplenial cortex: intrinsic connectiviuty and connections with the (para)hippocampal region in the rat. An interactive connectome

Sugar, Jørgen Larsen; Witter, Menno; van Strien, Niels; Cappaert, Natalie L.M.
Journal article, Peer reviewed
Published version
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URI
http://hdl.handle.net/11250/2621521
Date
2011
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  • Institutt for nevromedisin og bevegelsesvitenskap [1645]
  • Institutt for sirkulasjon og bildediagnostikk [1012]
  • Kavliinstitutt for nevrovitenskap [171]
  • Publikasjoner fra CRIStin - NTNU [19793]
Original version
10.3389/fninf.2011.00007
Abstract
A connectome is an indispensable tool for brain researchers, since it quickly provides comprehensive knowledge of the brain’s anatomical connections. Such knowledge lies at the basis of understanding network functions. Our first comprehensive and interactive account of brain connections comprised the rat hippocampal–parahippocampal network. We have now added all anatomical connections with the retrosplenial cortex (RSC) as well as the intrinsic connections of this region, because of the interesting functional overlap between these brain regions. The RSC is involved in a variety of cognitive tasks including memory, navigation, and prospective thinking, yet the exact role of the RSC and the functional differences between its subdivisions remain elusive. The connectome presented here may help to define this role by providing an unprecedented interactive and searchable overview of all connections within and between the rat RSC, parahippocampal region and hippocampal formation.
Publisher
Frontiers Media
Journal
Frontiers in Neuroinformatics

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