Browsing St. Olavs hospital by Title
Now showing items 2042-2061 of 2452
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Semiquantitative Real-Time PCR to Distinguish Pneumocystis Pneumonia from Colonization in a Heterogeneous Population of HIV-Negative Immunocompromised Patients
(Peer reviewed; Journal article, 2021)Pneumocystis jirovecii is a threat to iatrogenically immunosuppressed individuals, a heterogeneous population at rapid growth. We assessed the ability of an in-house semiquantitative real-time PCR assay to discriminate ... -
Sentenced to die in prison: Reflections on whole life orders
(Peer reviewed; Journal article, 2022) -
Separating parental and treatment contributions to perinatal health after fresh and frozen embryo transfer in assisted reproduction: A cohort study with within-sibship analysis
(Peer reviewed; Journal article, 2021)Background Compared to naturally conceived children, adverse perinatal outcomes are more common among children born after assisted reproductive technology with fresh embryo transfer (fresh-ET) or frozen embryo transfer ... -
Separating the genetics of childhood and adult obesity: a validation study of genetic scores for body mass index in adolescence and adulthood in the HUNT Study
(Peer reviewed; Journal article, 2020)From a life-course perspective, genetic and environmental factors driving childhood obesity may have a lasting inf luence on health later in life. However, how obesity trajectories vary throughout the life-course remains ... -
Serotonin—A Driver of Progressive Heart Valve Disease
(Peer reviewed; Journal article, 2022)It is well known that some serotoninergic drugs and neuroendocrine tumors producing serotonin (5-HT) may induce valvular heart disease by stimulation of proliferation of valvular cells via interaction with a 5-HT receptor ... -
Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomization analysis of the HUNT study
(Journal article; Peer reviewed, 2018)We aimed to investigate potential causal associations between serum 25-hydroxyvitamin D [25(OH)D] levels and incidence of lung cancer overall and histologic types. We performed a Mendelian randomization (MR) analysis using ... -
Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: An observational study Cancer palliative care
(Peer reviewed; Journal article, 2015)Background:The feasibility and clinical implication of drug monitoring of morphine, morphine-6-glucuronide (M6G)and morphine-3-glucuronide (M3G) need further investigation. This study aimed to determine what predicts ... -
Serum Concentrations of Selected Poly- and Perfluoroalkyl Substances (PFASs) in Pregnant Women and Associations with Birth Outcomes. A Cross-Sectional Study from Southern Malawi
(Journal article; Peer reviewed, 2023)Pervasive exposure to per-and polyfluoroalkyl substances (PFASs) shows associations with adverse pregnancy outcomes. The aim of the present study was to examine the determinants of different serum PFAS concentrations in ... -
Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
(Journal article; Peer reviewed, 2018)Background The IL-6 receptor antagonist tocilizumab has been shown to attenuate the proatherogenic lipoprotein a [Lp(a)] in rheumatoid arthritis. We evaluated if a single dose of tocilizumab reduced Lp(a) in patients with ... -
Serum metabolome associated with severity of acute traumatic brain injury
(Peer reviewed; Journal article, 2022)Complex metabolic disruption is a crucial aspect of the pathophysiology of traumatic brain injury (TBI). Associations between this and systemic metabolism and their potential prognostic value are poorly understood. Here, ... -
Serum neurofilament as a predictor of 10-year grey matter atrophy and clinical disability in multiple sclerosis: a longitudinal study
(Peer reviewed; Journal article, 2022)Background - The predictive value of serum neurofilament light chain (sNfL) on long-term prognosis in multiple sclerosis (MS) is still unclear. Objective - Investigate the relation between sNfL levels over a 2-year period ... -
Serum NMR-Based Metabolomics Profiling Identifies Lipoprotein Subfraction Variables and Amino Acid Reshuffling in Myeloma Development and Progression
(Peer reviewed; Journal article, 2023)Multiple myeloma (MM) is an incurable hematological cancer. It is preceded by monoclonal gammopathy of uncertain significance (MGUS)—an asymptomatic phase. It has been demonstrated that early detection increases the 5-year ... -
Serum or Plasma for Quantification of Direct Oral Anticoagulants?
(Peer reviewed; Journal article, 2022)Background: Direct oral anticoagulants are increasingly replacing vitamin K antagonists for prevention of stroke in patients with atrial fibrillation, partly owing to the lack of a need for routine monitoring. Therapeutic ... -
Serumkonsentrasjonsmåling av gentamicin hos barn
(Peer reviewed; Journal article, 2023)BAKGRUNN Gentamicin brukes ofte ved alvorlige infeksjoner hos barn. Det har værtrutine i Norge å måle serumkonsentrasjon av gentamicin re før andre ellertredje dose (0-prøve) for å vurdere risiko fortoksisitet. Den ... -
Serumkonsentrasjonsmåling av gentamicin hos barn
(Peer reviewed; Journal article, 2023)BAKGRUNN Gentamicin brukes ofte ved alvorlige infeksjoner hos barn. Det har vært rutine i Norge å måle serumkonsentrasjon av gentamicin rett før andre eller tredje dose (0-prøve) for å vurdere risiko for toksisitet. Den ... -
Severe bradycardia and hypotension in anaesthetized pigs: Possible interaction between octreotide, xylazine, and atropine: A case series
(Peer reviewed; Journal article, 2023)Pigs are common animal models in diabetes research. Streptozotocin-induced destruction of pancreatic β-cells is used to induce diabetes in conscious pigs. However, in short-term non-recovery experiments, suppression of ... -
Severe traumatic brain injury in Norway: impact of age on outcome
(Journal article; Peer reviewed, 2013)Objective: The aim of this study was to investigate the influence of age on mortality and 3-month outcome in a Norwegian cohort of patients with severe traumatic brain injury (TBI). Methods: Norwegian residents ≥ 16 years ... -
Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder
(Peer reviewed; Journal article, 2022)Girls and boys might differ in autistic symptoms and associated cognitive difficulties such as executive function (EF). We investigated sex differences in the relationship between parent rated EF and autistic symptoms in ... -
Sex Differences and Similarities in Risk Factors of Physical Aggression in Adolescence
(Peer reviewed; Journal article, 2022)Considerable research has documented risk factors of physical aggression in adolescence. However, less is known of sex differences in these associations. The current study addressed this important area by examining sex ... -
Sex hormones and sperm parameters after adjuvant oxaliplatin-based treatment for colorectal cancer
(Peer reviewed; Journal article, 2022)Background The incidence of colorectal cancer (CRC) in individuals of fertile age is increasing. Oxaliplatin is a cornerstone treatment in the adjuvant setting for stage III and high-risk stage II CRC. Limited data exist ...