Vis enkel innførsel

dc.contributor.authorIldstad, Fredrik
dc.contributor.authorEllekjær, Hanne
dc.contributor.authorWethal, Torgeir
dc.contributor.authorLydersen, Stian
dc.contributor.authorSund, Janne Kutschera
dc.contributor.authorFjærtoft, Hild
dc.contributor.authorSchüler, Stephan
dc.contributor.authorHorn, Jens
dc.contributor.authorBråthen, Geir
dc.contributor.authorMidtsæther, Ann-Grete
dc.contributor.authorMorsund, Åse Hagen
dc.contributor.authorLillebø, Marja-Liisa
dc.contributor.authorSeljeseth, Yngve Müller
dc.contributor.authorIndredavik, Bent
dc.date.accessioned2019-04-10T06:11:45Z
dc.date.available2019-04-10T06:11:45Z
dc.date.created2019-01-23T21:11:26Z
dc.date.issued2019
dc.identifier.issn1471-2377
dc.identifier.urihttp://hdl.handle.net/11250/2593918
dc.description.abstractBackground Transient ischemic attack (TIA) is a risk factor of stroke. Modern treatment regimens and changing risk factors in the population justify new estimates of stroke risk after TIA, and evaluation of the recommended ABCD2 stroke risk score. Methods From October, 2012, to July, 2014, we performed a prospective, multicenter study in Central Norway, enrolling patients with a TIA within the previous 2 weeks. Our aim was to assess stroke risk at 1 week, 3 months and 1 year after TIA, and to determine the predictive value of the dichotomized ABCD2 score (0–3 vs 4–7) at each time point. We used data obtained by telephone follow-up and registry data from the Norwegian Stroke Register. Results Five hundred and seventy-seven patients with TIA were enrolled of which 85% were examined by a stroke specialist within 24 h after symptom onset. The cumulative incidence of stroke within 1 week, 3 months and 1 year of TIA was 0.9% (95% CI, 0.37–2.0), 3.3% (95% CI, 2.1–5.1) and 5.4% (95% CI, 3.9–7.6), respectively. The accuracy of the ABCD2 score provided by c-statistics at 7 days, 3 months and 1 year was 0.62 (95% CI, 0.39–0.85), 0.62 (95% CI, 0.51–0.74) and 0.64 (95% CI, 0.54–0.75), respectively. Conclusions We found a lower stroke risk after TIA than reported in earlier studies. The ABCD2 score did not reliably discriminate between low and high risk patients, suggesting that it may be less useful in populations with a low risk of stroke after TIA.nb_NO
dc.language.isoengnb_NO
dc.publisherBioMed Centralnb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleStroke risk after transient ischemic attack in a Norwegian prospective cohortnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.journalBMC Neurologynb_NO
dc.identifier.doi10.1186/s12883-018-1225-y
dc.identifier.cristin1664028
dc.description.localcode© The Author(s). 2019. Open Access. Attribution 4.0 International (CC BY 4.0)nb_NO
cristin.unitcode194,65,30,0
cristin.unitcode194,65,35,5
cristin.unitcode194,65,15,0
cristin.unitcode194,65,20,0
cristin.unitnameInstitutt for nevromedisin og bevegelsesvitenskap
cristin.unitnameRKBU Midt-Norge - Regionalt kunnskapssenter for barn og unge - psykisk helse og barnevern
cristin.unitnameInstitutt for klinisk og molekylær medisin
cristin.unitnameInstitutt for samfunnsmedisin og sykepleie
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Navngivelse 4.0 Internasjonal
Med mindre annet er angitt, så er denne innførselen lisensiert som Navngivelse 4.0 Internasjonal