Detection of Vulnerable Atherosclerotic Plaque
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Heart attacks are the cause for the majority of deaths in the industrialized world. The underlying cause of most of these deaths is the rupture of vulnerable plaque. As of this day, no widely accepted clinical tool exists for detecting plaques that are prone to rupture, although several techniques are being investigated. This thesis gives an overview of detection modalities that have been proposed for detecting vulnerable plaque with special emphasis on three methods, diffuse reflection spectroscopy, thermography and multiphoton microscopy.
Has partsLilledahl, Magnus Borstad; Haugen, Olav A.; Randeberg, Lise L.; Svaasand, Lars O.. Characterization of atherosclerotic plaque by reflection spectroscopy and thermography: A comparison. Proceedings of SPIE. 5686: 415-425, 2005.
Lilledahl, Magnus Borstad; Barkost, Marianne; Gran, Mari W.; Haugen, Olav A.; Svaasand, Lars O.. The effect of a thin bloodlayer on fluorescence spectroscopy. Proceedings of SPIE. 6078: 60782J-1, 2006.
Lilledahl, Magnus Borstad; Haugen, Olav A.; Barkost, Marianne; Svaasand, Lars O.. Reflection spectroscopy of atherosclerotic plaque. Journal of Biomedical Optics. 11(2): 021005, 2006.
Lilledahl, Magnus Borstad; Larsen, Eivind L.P.; Svaasand, Lars O.. An analytic and numerical study of intravascular thermography of vulnerable plaque. Phys. Med. Biol.. 52: 961-979, 2007.