Now showing items 311-330 of 343

    • The Effects of Short-Term Sleep Restriction on Proactive and Reactive Cognitive Control Regions 

      Habli, Sarah (Master thesis, 2020)
      Proaktiv og reaktiv kontroll er to modus av kognitiv kontroll som fungerer på ulike tidsskalaer og aktiverer både overlappende og distinkte hjerneregioner. Ingen tidligere studier har undersøkt hvordan hjerneregioner knyttet ...
    • The Egocentric Hippocampus 

      Carpenter, Jordan (Master thesis, 2021)
      Navigation relies on the integration of incoming sensory information with a stable schema that can be applied to map the current environment. This integration results in a dynamic map of the animal’s position based on ...
    • The Hippocampus Encodes Distances in Multidimensional Feature Space 

      Theves, Stephanie; Fernandez, Guillen; Doeller, Christian Fritz Andreas (Journal article; Peer reviewed, 2019)
      The hippocampal formation encodes maps of the physical environment [1, 2, 3, 4, 5]. A key question in neuroscience is whether its spatial coding principles also provide a universal metric for the organization of non-spatial ...
    • The long-term stability of new hippocampal place fields requires new protein synthesis. 

      Agnihotri, Naveen; Hawkins, Robert; Kandel, ER; Kentros, Clifford (Journal article; Peer reviewed, 2004)
      The hippocampus is critical for formation of spatial memories. Hippocampal pyramidal neurons in freely behaving animals exhibit spatially selective firing patterns, which taken together form an internal representation of ...
    • The nucleus reuniens of the thalamus sits at the nexus of a hippocampus and medial prefrontal cortex circuit enabling memory and behavior 

      Dolleman-van der Weel, Margriet J.; Griffin, Amy L.; Ito, Hiroshi; Shapiro, Matthew L.; Witter, Menno; Vertes, Robert P.; Allen, Timothy A. (Journal article; Peer reviewed, 2019)
      The nucleus reuniens of the thalamus (RE) is a key component of an extensive network of hippocampal and cortical structures and is a fundamental substrate for cognition. A common misconception is that RE is a simple relay ...
    • The retrosplenial cortex: intrinsic connectiviuty and connections with the (para)hippocampal region in the rat. An interactive connectome 

      Sugar, Jørgen Larsen; Witter, Menno; van Strien, Niels; Cappaert, Natalie L.M. (Journal article; Peer reviewed, 2011)
      A connectome is an indispensable tool for brain researchers, since it quickly provides comprehensive knowledge of the brain’s anatomical connections. Such knowledge lies at the basis of understanding network functions. Our ...
    • The Role of Cilia on Zebrafish Olfaction & Behaviour 

      Ege, Mert (Master thesis, 2020)
      The cilium is a ubiquitous organelle found across species on a wide range of cell types. It is a highly varied structure able to fulfill a plethora of functions; from motile cilia serving in cell motility and establishing ...
    • The role of dorsal raphe nucleus and serotonin in fear conditioning 

      Strandhagen, Peter Wessel (Master thesis, 2020)
      Lærings- og hukommelsesprosesser er avgjørende for å overleve for enhver art, og evnen til å lære og forutsi hvilke situasjoner eller miljømessige sammenhenger som er lønnsomme eller farlige kan være fordelaktig. Både ...
    • The Role of Hippocampal Cajal-Retzius Cells in Pyramidal Neuron Maturation 

      Glærum, Ingvild L. (Master thesis, 2021)
      Hippocampusformasjonen er en hjernestruktur som er anerkjent for sin rolle i minnedannelse, læring og representasjon av rom. Ved å studere utviklingen av hippocampus-kretsen, kan vi bygge en forståelse av de nødvendige ...
    • The role of hippocampal spatial representations in contextualization and generalization of fear 

      Lycia, D. de Voogd; Doeller, Christian Fritz Andreas; P.J.Murray, Yannick; M. Barte, Ramona; van der Heide, Anouk; Fernandez, Guillen; J. Hermans, Erno (Journal article; Peer reviewed, 2019)
      Using contextual information to predict aversive events is a critical ability that protects from generalizing fear responses to safe contexts. Animal models have demonstrated the importance of spatial context representations ...
    • The role of mental maps in decision-making 

      Kaplan, Raphael; Schuck, Nicolas W.; Doeller, Christian F. (Journal article; Peer reviewed, 2017)
      A growing body of work is investigating the use of mental maps during decision-making. Here we discuss how decision-making organizes experiences according to an internal model of the current task, thereby structuring memory. ...
    • The spatial representations acquired in CA3 by self-organizing recurrent connections 

      Cerasti, Erika; Treves, Alessandro (Journal article; Peer reviewed, 2013)
      Neural computation models have hypothesized that the dentate gyrus (DG) drives the storage in the CA3 network of new memories including, e.g., in rodents, spatial memories. Can recurrent CA3 connections self-organize, ...
    • The Stochastic Complexity of Spin Models: Are Pairwise Models Really Simple? 

      Beretta, Alberto; Battistin, Claudia; de Mulatier, Clelia; Mastromatteo, Iacopo; Marsili, Matteo (Journal article; Peer reviewed, 2018)
      Models can be simple for different reasons: because they yield a simple and computationally efficient interpretation of a generic dataset (e.g., in terms of pairwise dependencies)—as in statistical learning—or because they ...
    • The Subthalamic Nucleus: Unravelling New Roles and Mechanisms in the Control of Action 

      Bonnevie, Tora; Zaghloul, Kareem (Journal article; Peer reviewed, 2018)
      How do we decide what we do? This is the essence of action control, the process of selecting the most appropriate response among multiple possible choices. Suboptimal action control can involve a failure to initiate or ...
    • The Time Window for Generation of Dendritic Spikes by Coincidence of Action Potentials and EPSPs is Layer Specific in Somatosensory Cortex 

      Ledergerber, Debora; Larkum, Matthew Evan (Journal article; Peer reviewed, 2012)
      The precise timing of events in the brain has consequences for intracellular processes, synaptic plasticity, integration and network behaviour. Pyramidal neurons, the most widespread excitatory neuron of the neocortex have ...
    • Theta phase-coordinated memory reactivation reoccurs in a slow-oscillatory rhythm during NREM sleep 

      Schreiner, Thomas; Doeller, Christian Fritz Andreas; Jensen, Ole; Rasch, Björn; Staudigl, Tobias (Journal article; Peer reviewed, 2018)
      It has been proposed that sleep’s contribution to memory consolidation is to reactivate prior encoded information. To elucidate the neural mechanisms carrying reactivation-related mnemonic information, we investigated ...
    • Topography of Place Maps along the CA3-to-CA2 Axis of the Hippocampus 

      Lu, Li; Igarashi, Kei M; Witter, Menno; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2015)
      We asked whether the structural heterogeneity of the hippocampal CA3-CA2 axis is reflected in how space is mapped onto place cells in CA3-CA2. Place fields were smaller and sharper in proximal CA3 than in distal CA3 and ...
    • Toroidal topology of population activity in grid cells 

      Gardner, Richard J.; Hermansen, Erik; Pachitariu, Marius; Burak, Yoram; Baas, Nils A.; Dunn, Benjamin Adric; Moser, May-Britt; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2022)
      The medial entorhinal cortex is part of a neural system for mapping the position of an individual within a physical environment1. Grid cells, a key component of this system, fire in a characteristic hexagonal pattern of ...
    • Towards modeling of neuronal networks in HUWE1-induced XLID 

      Ask, Torvald Fossåen (Master thesis, 2020)
      Intellektuell forstyrrelse (ID) er en utviklingsforstyrrelse karakterisert av manglende intellektuelle funksjoner og adaptive evner. Denne lidelsen rammer tilnærmet 2% av den vestlige populasjonen. X-koblet ID (XLID) er ...
    • Trans-Synaptic Spread of Tau Pathology In Vivo 

      Liu, L; Drouet, V; Wu, JW; Witter, Menno; Small, Scott A; Clelland, C; Duff, K (Journal article; Peer reviewed, 2012)
      Tauopathy in the brain of patients with Alzheimer’s disease starts in the entorhinal cortex (EC) and spreads anatomically in a defined pattern. To test whether pathology initiating in the EC spreads through the brain along ...