• Perirhinal firing patterns are sustained across large spatial segments of the task environment 

      Bos, Jeroen J.; Vinck, Martin; van Mourik-Donga, Laura; Jackson, Jadin C.; Witter, Menno; Pennartz, Cyriel M.A. (Journal article; Peer reviewed, 2017)
      Spatial navigation and memory depend on the neural coding of an organism’s location. Fine-grained coding of location is thought to depend on the hippocampus. Likewise, animals benefit from knowledge parsing their environment ...
    • Phase transitions and asymmetry between signal comprehension and production in biological communication 

      Salahshour, Mohammad; Rouhani, Shahin; Roudi, Yasser (Journal article; Peer reviewed, 2019)
      We introduce a model for collective information acquisition from the environment, in a biological population. In this model, individuals can make noisy observations of the environment, and communicate their observation by ...
    • Physical navigation through a conceptual space 

      St. John, Natalie (Master thesis, 2019)
      Navigation of a physical space is facilitated by spatially tuned neurons in the hippocampal formation. These cells are thought to instantiate a cognitive map, affording an animal with an internal representation of its ...
    • Physiological properties of neurons in bat entorhinal cortex exhibit an inverse gradient along the dorsal–ventral axis compared to entorhinal neurons in rat 

      Heys, James G; Shay, Christopher F; MacLeod, Katrina M; Witter, Menno; Moss, Cynthia F; Hasselmo, Michael E (Journal article; Peer reviewed, 2016)
      Medial entorhinal cortex (MEC) grid cells exhibit firing fields spread across the environment on the vertices of a regular tessellating triangular grid. In rodents, the size of the firing fields and the spacing between the ...
    • Place Cell Rate Remapping by CA3 Recurrent Collaterals 

      Solstad, Trygve; Yousif, HN; Sejnowski, TJ (Journal article; Peer reviewed, 2014)
      Episodic-like memory is thought to be supported by attractor dynamics in the hippocampus. A possible neural substrate for this memory mechanism is rate remapping, in which the spatial map of place cells encodes contextual ...
    • Place cells in the hippocampus: Eleven maps for eleven rooms 

      Alme, Charlotte; Miao, Chenglin; Jezek, Karel; Treves, Alessandro; Moser, Edvard Ingjald; Moser, May-Britt (Journal article; Peer reviewed, 2014)
      The contribution of hippocampal circuits to high-capacity episodic memory is often attributed to the large number of orthogonal activity patterns that may be stored in these networks. Evidence for high-capacity storage in ...
    • Place cells, grid cells, and memory 

      Moser, May-Britt; Rowland, David Clayton; Moser, Edvard Ingjald (Journal article; Peer reviewed, 2015)
      The hippocampal system is critical for storage and retrieval of declarative memories, including memories for locations and events that take place at those locations. Spatial memories place high demands on capacity. Memories ...
    • Placental inflammation by HMGB1 activation of TLR4 at the syncytium 

      Tangerås, Line Haugstad; Silva, Gabriela; Stødle, Guro; Gierman, Lobke; Skei, Bente; Collett, Karin; Beversmark, Anne Lise; Skråstad, Ragnhild Bergene; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2018)
      Introduction: Normal pregnancy is characterized by an elevated inflammatory state involving the placenta. The placental inflammation is further increased in preeclampsia, resulting in release of harmful danger signals to ...
    • Placental inflammation by HMGB1 activation of TLR4 at the syncytium 

      Tangerås, Line Haugstad; Silva, Gabriela; Stødle, Guro; Gierman, Lobke; Skei, Bente; Collett, Karin; Beversmark, Anne Lise; Skråstad, Ragnhild Bergene; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2018)
      Normal pregnancy is characterized by an elevated inflammatory state involving the placenta. The placental inflammation is further increased in preeclampsia, resulting in release of harmful danger signals to the maternal ...
    • Plasticity of hippocampal memories in humans 

      Horner, Aidan J.; Doeller, Christian F. (Journal article; Peer reviewed, 2017)
      The human hippocampus is a brain region that supports episodic and spatial memory. Recent experiments have drawn on animal research and computational modelling to reveal how the unique computations and representations of ...
    • Posterior parietal cortex 

      Whitlock, Jonathan (Journal article; Peer reviewed, 2017)
      The posterior parietal cortex, along with temporal and prefrontal cortices, is one of the three major associative regions in the cortex of the mammalian brain. It is situated between the visual cortex at the caudal pole ...
    • Posterior parietal cortex of the rat: Architectural delineation and thalamic differentiation 

      Olsen, Grethe Mari; Witter, Menno (Journal article; Peer reviewed, 2016)
      This study refines the characterization of the rat parietal cortical domain in terms of cyto- and chemoarchitecture as well as thalamic connectivity. We recognize three subdivisions of the posterior parietal cortex (PPC), ...
    • Postnatal Development of Functional Projections from Parasubiculum and Presubiculum to Medial Entorhinal Cortex in the Rat 

      Canto, Cathrin Barbara; Koganezawa, Noriko; Lagartos-Donate, Maria Jose; O'Reilly, Kally; Mansfelder, Huibert D; Witter, Menno (Journal article; Peer reviewed, 2019)
      Neurons in parasubiculum (PaS), presubiculum (PrS), and medial entorhinal cortex (MEC) code for place (grid cells) and head direction. Directional input has been shown to be important for stable grid cell properties in ...
    • Postnatal Development of Projections of the Postrhinal Cortex to the Entorhinal Cortex in the Rat 

      Donate Lagartos, Maria Jose; Doan, Thanh Pierre; Bettencourt, Girao Paulo Jorge; Witter, Menno (Journal article; Peer reviewed, 2022)
    • Postnatal development of retrosplenial projections to the parahippocampal region of the rat 

      Sugar, Jørgen; Witter, Menno (Journal article; Peer reviewed, 2016)
      The rat parahippocampal region (PHR) and retrosplenial cortex (RSC) are cortical areas important for spatial cognition. In PHR, head-direction cells are present before eye-opening, earliest detected in postnatal day (P)11 ...
    • Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming 

      Bergmann, Tobias; Liu, Yong; Skov, Jonathan; Mogus, Leo; Lee, Julie; Pfisterer, Ulrich; Handfield, Louis-Francois; Asenjo-Martinez, Andrea; Lisa-Vargas, Irene; Seemann, Stefan E.; Lee, Jimmy Tsz Hang; Patikas, Nikolaos; Kornum, Birgitte Rahbek; Denham, Mark; Hyttel, Poul; Witter, Menno; Gorodkin, Jan; Pers, Tune H.; Hemberg, Martin; Khodosevich, Konstantin; Hall, Vanessa Jane (Journal article; Peer reviewed, 2022)
    • Projections from somatosensory areas to perirhinal cortex in the mouse 

      Kasper Kjelsberg (Master thesis, 2019)
      Abstract The perirhinal cortex (PER) is an association area belonging to the medial temporal lobe and is situated along the rhinal sulcus on the lateral surface of rodent brain. Perirhinal cortex can be divided into area ...
    • Projections of the insular cortex to orbitofrontal and medial prefrontal cortex: A tracing study in the rat 

      Mathiasen, Mathias; Aggleton, John P.; Witter, Menno Peter (Peer reviewed; Journal article, 2023)
      The dense fiber pathways that connect the insular cortex with frontal cortices are thought to provide these frontal areas with interoceptive information, crucial for their involvement in executive functions. Using anterograde ...
    • Quantifying the parvalbumin-positive interneurons in the rodent lateral and medial entorhinal cortex 

      Laja, Arthur (Master thesis, 2019)
      The entorhinal cortex (EC) has been implicated in many functions related to spatial navigation, memory, and the perception of time. It is the major input and output pathway to the hippocampus, and this puts an enormous ...
    • Rapid encoding of task regularities in the human hippocampus guides sensorimotor timing 

      Polti, Ignacio; Nau, Matthias; Kaplan, Raphael; van Wassenhove, Virginie; Doeller, Christian Fritz Andreas (Peer reviewed; Journal article, 2022)
      The brain encodes the statistical regularities of the environment in a task-specific yet flexible and generalizable format. Here, we seek to understand this process by bridging two parallel lines of research, one centered ...