• Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking 

      Sofias, Alexandros Marios; Toner, Yohana C.; Meerwaldt, Anu E.; van Leent, Mandy M. T.; Soultanidis, Georgios; Elschot, Mattijs; Gonai, Haruki; Grendstad, Kristin; Flobak, Åsmund; Neckmann, Ulrike; Wolowczyk, Camilla; Fisher, Elizabeth L.; Reiner, Thomas; Davies, Catharina de Lange; Bjørkøy, Geir; Teunissen, Abraham J. P.; Ochando, Jordi; Pérez-Medina, Carlos; Mulder, Willem J. M.; Hak, Sjoerd (Journal article; Peer reviewed, 2020)
      Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ...
    • Two-Dimensional Blood Velocity Estimation for Intracardiac Flow Assessment 

      Fadnes, Solveig (Doktoravhandlinger ved NTNU, 1503-8181; 2014:260, Doctoral thesis, 2014)
      Måling av blodstrømshastigheter i hjertet Ultralyd (ekkokardiografi) og fargedoppler er viktige verktøy som brukes for å detektere og visualisere medfødt hjertefeil. To av de mest vanlige formene for medfødt hjertefeil ...
    • Ubiquitin-proteasome-system and enzymes of energy metabolism in skeletal muscle of patients with HFpEF and HFrEF 

      Adams, Volker; Wunderlich, Sebastian; Mangner, Norman; Hommel, Jennifer; Esefeld, Katrin; Gielen, Stephan; Halle, Martin; Ellingsen, Øyvind; Van Craenenbroeck, Emeline M.; Wisløff, Ulrik; Pieske, Burkert; Linke, Axel; Winzer, Ephraim (Peer reviewed; Journal article, 2021)
      Background Skeletal muscle (SM) alterations contribute to exercise intolerance in heart failure patients with preserved (HFpEF) or reduced (HFrEF) left ventricular ejection fraction (LVEF). Protein degradation via the ...
    • Ultra-high frame rate tissue Doppler imaging, technical feasibility and first clinical experiences 

      Lervik, Lars Christian Naterstad (Doctoral theses at NTNU;2017:332, Doctoral thesis, 2017)
    • Ultrasonic detection of decompression induced vascular microbubbles 

      Eftedal, Olav Sande (Doktoravhandlinger ved NTNU, 1503-8181; 2007:168, Doctoral thesis, 2007)
      Gassbobler kan dannes i kroppen som følge av overmetning av gasser når man går opp til overflaten etter dykking. Det har lenge vært kjent at slike gassbobler kan føre til trykkfallsyke, men mekanismene bak er fortsatt ikke ...
    • Ultrasonic focusing through a steel layer for acoustic imaging 

      Talberg, Andreas Sørbrøden; Dong, Hefeng; Johansen, Tonni Franke; Måsøy, Svein-Erik; Brekke, Svein; Rommetveit, Tarjei (Journal article; Peer reviewed, 2018)
      Ultrasonic tools are being used for imaging in a large variety of fields, spanning from medical applications in a hospital to applications deep down in oil and gas wells. When applying ultrasonic imaging techniques to image ...
    • Ultrasonic well integrity logging using phased array technology 

      Johansen, Tonni Franke; Buschmann, Philip Erik; Røsberg, Knut Marius; Diez, Anja; Viggen, Erlend Magnus (Chapter, 2023)
      Ultrasonic well integrity logging is an important and common procedure for well completion and plug-and-abandonment operations. Typical logging tools employ single-element ultrasound transducers. In medical ultrasound ...
    • Ultrasound and magnetic resonance imaging for group stratification and treatment monitoring in the transgenic adenocarcinoma of the mouse prostate model 

      Fagerland, Stein-Martin Tilrum; Hill, Deborah Katherine; van Wamel, Annemieke; Davies, Catharina de Lange; Kim, Jana (Journal article; Peer reviewed, 2020)
      Background:The transgenic adenocarcinoma of the mouse prostate (TRAMP) is a widelyused genetically engineered spontaneous prostate cancer model. However, both thedegree of malignancy and time of cancer onset vary. While ...
    • Ultrasound cardiac modeling, segmentation and tracking 

      Dikici, Engin (Doktoravhandlinger ved NTNU, 1503-8181; 2013:79, Doctoral thesis, 2013)
      Echocardiography plays a key role in assessing cardiac diseases, especially in evaluating left ventricular (LV) function. It enables real-time, non-invasive, and relatively low cost acquisition of cardiac images. Furthermore, ...
    • Ultrasound detection of vascular decompression bubbles: The influence of new technology and considerations on bubble load 

      Blogg, Lesley S; Gennser, Mikael; Møllerløkken, Andreas; Brubakk, Alf O (Journal article; Peer reviewed, 2014)
      INTRODUCTION: Diving often causes the formation of 'silent' bubbles upon decompression. If the bubble load is high, then the risk of decompression sickness (DCS) and the number of bubbles that could cross to the arterial ...
    • Ultrasound imaging in neurosurgery: Delineation of tumours for resection control 

      Selbekk, Tormod (Doktoravhandlinger ved NTNU, 1503-8181; 2013:85, Doctoral thesis, 2013)
      Complete removal, as opposed to only partial removal, of all macroscopic tumor tissue is associated with longer survival for most of the brain tumours. Ultrasound is an imaging technique that can contribute to increase the ...
    • Ultrasound imaging of blood flow based on high frame rate acquisition and adaptive signal processing 

      Ekroll, Ingvild Kinn (Doktoravhandlinger ved NTNU, 1503-8181; 2013:54, Doctoral thesis, 2013)
      Ultrasound imaging of blood flow is in widespread use for assessment of atherosclerotic disease. Imaging of the carotid arteries is of special interest, as blood clots from atherosclerotic plaques may follow the blood ...
    • Ultrasound Improves the Delivery and Therapeutic Effect of Nanoparticle-Stabilized Microbubbles in Breast Cancer Xenografts 

      Snipstad, Sofie; Berg, Sigrid; Mørch, Ýrr Asbjørg; Bjørkøy, Astrid; Sulheim, Einar; Hansen, Rune; Grimstad, Ingeborg; van Wamel, Annemieke; Maaland, Astri Fjelde; Torp, Sverre Helge; Davies, Ruth Catharina de Lange (Journal article; Peer reviewed, 2017)
      Compared with conventional chemotherapy, encapsulation of drugs in nanoparticles can improve efficacy and reduce toxicity. However, delivery of nanoparticles is often insufficient and heterogeneous because of various ...
    • Ultrasound in image-guided spine surgery: Enabling technologies and first steps 

      Bø, Lars Eirik (Doctoral theses at NTNU;2018:257, Doctoral thesis, 2018)
      Most people experience back pain at some point in their life. While most of these conditions are treated nonoperatively, surgical treatment has been shown to be both effective and cost effective compared to nonoperative ...
    • Ultrasound speckle reduction using generative adversial networks 

      Dietrichson, Fabian Sødal; Smistad, Erik; Østvik, Andreas; Løvstakken, Lasse (Journal article; Peer reviewed, 2018)
      Generative adversial networks (GANs) have shown its ability to create realistic and accurate image-to-image transformation. The goal of this work was to investigate whether deep convolutional GANs can learn to perform ...
    • Ultrasound Strain Rate Imaging of Individual Muscle Motor Units 

      Heger, Max; Stavdahl, Øyvind; Torp, Hans (Journal article; Peer reviewed, 2014)
      Skeletal muscle is organized in motor units, each comprising a motor neuron and all its connected muscle fibres. The arrival of an action potential (a neural “impulse”) causes the fibers to contract, they exhibit a twitch. ...
    • Ultrasound-based Estimation of Strain in Abdominal Aortic Aneurysm 

      Brekken, Reidar (Doktoravhandlinger ved NTNU, 1503-8181; 2012:369, Doctoral thesis, 2012)
      Abdominal aortic aneurysm (AAA) is a vascular disease resulting in a permanent local dilatation of the abdominal aorta. Different studies estimate the prevalence of AAA to 1.3-8.9% of men and 1.0-2.2% of women over 60 years ...
    • Ultrasound-based quantification of myocardial deformation and rotation 

      Crosby, Jonas (Doktoravhandlinger ved NTNU, 1503-8181; 2009:33, Doctoral thesis, 2009)
    • Ultrasound-mediated delivery and distribution of polymeric nanoparticles in the normal brain parenchyma of a metastatic brain tumour model 

      Baghirov, Habib; Snipstad, Sofie; Sulheim, Einar; Berg, Sigrid; Hansen, Rune; Thorsen, Frits; Mørch, Ýrr Asbjørg; Davies, Catharina de Lange; Åslund, Andreas (Journal article; Peer reviewed, 2018)
      The treatment of brain diseases is hindered by the blood-brain barrier (BBB) preventing most drugs from entering the brain. Focused ultrasound (FUS) with microbubbles can open the BBB safely and reversibly. Systemic drug ...
    • Ultrasound-mediated delivery enhances therapeutic efficacy of MMP sensitive liposomes 

      Olsman, Marieke; Sereti, Viktoria; Andreassen, Kristine; Snipstad, Linn Sofie; van Wamel, Johanna Elisabeth Theodora; Eliasen, Rasmus; Berg, Sigrid; Urquhart, Andrew J.; Andresen, Thomas L.; Davies, Ruth Catharina de Lange (Peer reviewed; Journal article, 2020)
      To improve therapeutic efficacy of nanocarrier drug delivery systems, it is essential to improve their uptake and penetration in tumour tissue, enhance cellular uptake and ensure efficient drug release at the tumour site. ...