Blar i Institutt for sirkulasjon og bildediagnostikk på tittel
Viser treff 1310-1329 av 1882
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Pharmacokinetic, pharmacodynamic and pharmacogenetic aspects of oxycodone treatment in cancer pain
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:167, Doctoral thesis, 2011) -
Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers
(Journal article; Peer reviewed, 2018)Purpose This study aimed to develop a model for pharmacodynamic and pharmacokinetic studies of naloxone antagonism under steady-state opioid agonism and to compare a high-concentration/low-volume intranasal naloxone ... -
Pharmacokinetics of a new, nasal formulation of naloxone
(Journal article; Peer reviewed, 2017)Purpose Nasal naloxone is wanted for bystander administration in opioid overdose and as a needle-free alternative for emergency medical personnel. Epidemiologic studies have indicated a therapeutic effect of bystander ... -
Pharmacokinetics of a novel, approved, 1.4-mg intranasal naloxone formulation for reversal of opioid overdose—a randomized controlled trial
(Peer reviewed; Journal article, 2019)Background and aims Intranasal (i.n.) naloxone is an established treatment for opioid overdose. Anyone likely to witness an overdose should have access to the antidote. We aimed to determine whether an i.n. formulation ... -
Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival from Sepsis
(Peer reviewed; Journal article, 2023)OBJECTIVES: Treatments that prevent sepsis complications are needed. Circulating lipid and protein assemblies—lipoproteins play critical roles in clearing pathogens from the bloodstream. We investigated whether early ... -
Pharmacological aspects of therapeutic hypothermia
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:174, Doctoral thesis, 2012)Terapeutisk hypotermi er foretrukket behandling av komatøse pasienter etter vellykket gjenoppliving fra hjertestans. Behandlingen består i å senke kroppstemperaturen til 33-34°C i 12-24 timer, og gis fordi den reduserer ... -
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma
(Peer reviewed; Journal article, 2021)Cancer cells often depend on microenvironment signals from molecules such as cytokines for proliferation and metabolic adaptations. PRL‐3, a cytokine‐induced oncogenic phosphatase, is highly expressed in multiple myeloma ... -
Physical activity and cardiorespiratory fitness as determinants of atrial fibrillation incidence and prognosis. Observational findings from the HUNT study
(Doctoral theses at NTNU;2020:110, Doctoral thesis, 2020)Atrieflimmer er en hjerterytmeforstyrrelse som karakteriseres ved rask og uregelmessig elektrisk aktivitet i hjertets forkamre. Tilstanden er meget utbredt med en forekomst på 2-3% i den voksne befolkningen, og middelaldrende ... -
Physical activity and exercise among older adults - The Generation 100 study
(Doctoral thesis at NTNU;2016:192, Doctoral thesis, 2016)SAMMENDRAG: De fleste land i verden vil fram mot år 2050 oppleve en demografisk endring, der andelen eldre personer vil øke sterkt. Denne demografiske endringen er forventet å øke helserelaterte kostnader, både fra et ... -
Physical Activity in Long-term Breast Cancer Survivors - a Mixed-Methods Approach
(Journal article; Peer reviewed, 2019)Objectives: Traditional methods measuring physical activity (PA) may misrepresent breast cancer survivors (BCSs) and low-socio-economic status (SES) groups. This study identifies PA-levels, routines and experiences among ... -
Physical activity modifies the risk of atrial fibrillation in obese individuals: The HUNT3 study
(Journal article; Peer reviewed, 2018)Background Atrial fibrillation is the most common heart rhythm disorder, and high body mass index is a well-established risk factor for atrial fibrillation. The objective of this study was to examine the associations of ... -
Physical activity, cardiovascular health and longevity in patients with metabolic syndrome
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:193, Doctoral thesis, 2011)TRENING FOR BEDRE HELSE HOS PERSONER MED METABOLSK SYNDROM Om lag hver tredje 50-åring i den vestlige verden har metabolsk syndrom, en tilstand hvor flere risikofaktorer for hjerte- og karsykdommer opptrer sammen. Personer ... -
Physical and physiological capacity of soccer players: Effects of strength and conditioning
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:83, Doctoral thesis, 2011) -
Physical therapy intervention in patients with non-cardiac chest pain following a recent cardiac event: A randomized controlled trial
(Journal article; Peer reviewed, 2015)Objectives: To assess the effect of two different physical therapy interventions in patients with stable coronary heart disease and non-cardiac chest pain. Methods: A randomized controlled trial was carried out at a ... -
Physicians’ Recognition and Management of Kidney Disease: A Randomized Vignette Study Evaluating the Impact of the KDIGO 2012 CKD Classification System
(Peer reviewed; Journal article, 2020)Rationale & Objective The Kidney Disease Outcome Quality Initiative (KDOQI) and Kidney Disease: Improving Global Outcomes (KDIGO) chronic kidney disease (CKD) classification systems published in 2002 and 2012, respectively, ... -
Physiological and Perceptual Responses to Single-player vs. Multiplayer Exergaming
(Peer reviewed; Journal article, 2022)Rationale: Since many modern exergames include a multiplayer component, this study aimed to compare the physiological and perceptual responses between playing a cycling exergame alone or with others. Methods: In this ... -
Physiological Genomics of Heart Failure: From Technology to Physiology
(Doktoravhandlinger ved NTNU, 1503-8181; 2007:84, Doctoral thesis, 2007)Genome wide gene expression in cardiac disease is incompletely characterized. The main purpose of this project was to increase insight into molecular mechanisms of myocardial hypertrophy and heart failure in experimental ... -
Physiological significance of pre- and post-ejection left ventricular tissue velocities and relations to mitral and aortic valve closures
(Peer reviewed; Journal article, 2021)Background: Tissue Doppler shows short duration velocity spikes during pre- and post-ejection (protodiastole). They have been assumed to be isovolumic contraction and relaxation movements, but this is not in accordance ... -
Pitfalls with the "chest compression-only" approach: the challenge of an unusual cause
(Journal article; Peer reviewed, 2010)Chest compression-only (CC-only) is now incorporated in the Norwegian protocol for dispatch guided CPR (cardiopulmonary resuscitation) in cardiac arrest of presumed cardiac aetiology. We present a case that is unique and ...