Now showing items 863-882 of 1877

    • Identification of novel genetic variants associated with cardiorespiratory fitness 

      Bye, Anja; Klevjer, Marie; Ryeng, Einar; Silva, Gustavo Jose Justo; Moreira, Jose Bianco Nascimento; Stensvold, Dorthe; Wisløff, Ulrik (Peer reviewed; Journal article, 2020)
      Introduction Low maximal oxygen uptake (VO2max) is a strong and independent risk factor for all-cause and cardiovascular disease (CVD) mortality. For other CVD risk factors, numerous genetic association studies have been ...
    • Identifying metabolic alterations in newly diagnosed small cell lung cancer patients 

      Pedersen, Shona; Hansen, Joachim Bavnhøj; Maltesen, Raluca Georgiana; Szejniuk, Weronica Maria; Andreassen, Trygve; Falkmer, Ursula; Kristensen, Søren Risom (Peer reviewed; Journal article, 2021)
      Background Small cell lung cancer (SCLC) is a malignant disease with poor prognosis. At the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is based on imaging, histopathology, and ...
    • Identifying possible biomarkers of lower urinary tract symptoms using metabolomics and partial least square regression 

      Hopland-Nechita, Florin Vasile; Andersen, John Roger; Rajalahti, Tarja; Andreassen, Trygve; Beisland, Christian (Peer reviewed; Journal article, 2023)
      Introduction The objective of this study was to explore potential novel biomarkers for moderate to severe lower urinary tract symptoms (LUTS) using a metabolomics-based approach, and statistical methods with significant ...
    • IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction 

      Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin; Damås, Jan Kristian; Espevik, Terje; Bendz, Bjørn; Halvorsen, Bente; Gregersen, Ida; Wiseth, Rune; Andersen, Geir Øystein; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Barratt-Due, Andreas; Mollnes, Tom Eirik (Journal article; Peer reviewed, 2018)
      Background: Elevated interleukin-6 (IL-6) and complement activation are associated with detrimental effects of inflammation in coronary artery disease (CAD). The complement anaphylatoxins C5a and C3a interact with their ...
    • Image Quality and Detectability in Siemens Biograph PET/MRI and PET/CT Systems - A Phantom study 

      Øen, Silje Kjærnes; Aasheim, Lars Birger; Eikenes, Live; Karlberg, Anna Maria (Journal article; Peer reviewed, 2019)
      Background The technology of modern positron emission tomography (PET) systems continuously improving, and with it the possibility to detect smaller lesions. Since first introduced in 2010, the number of hybrid PET/magnetic ...
    • Imaging of the temporomandibular joint in children with juvenile idiopathic arthritis; references and novel scoring systems for active and permanent disease 

      Angenete, Oskar W (Doctoral theses at NTNU;2022:121, Doctoral thesis, 2022)
      Sammendrag / Summary in Norwegian Bildediagnostikk av kjeveleddet hos barn med barneleddgikt; referansemateriale og skåringssystemer for å vurdere aktiv sykdom og permanent skade Barneleddgikt (juvenil idiopatisk artritt, ...
    • Immune and inflammatory responses to freediving calculated from leukocyte gene expression profiles 

      Eftedal, Ingrid; Flatberg, Arnar; Drvis, Ivan; Dujic, Zeljko (Journal article; Peer reviewed, 2016)
      Freedivers hold their breath while diving, causing blood oxygen levels to decrease (hypoxia) while carbon dioxide increases (hypercapnia). Whereas blood gas changes are presumably involved in the progression of respiratory ...
    • Impact of 2015 Earthquakes on a local hospital in Nepal: A Prospective Hospital-based Study 

      Giri, Samita; Risnes, Kari Ravndal; Uleberg, Oddvar; Rogne, Tormod; Shrestha, Sanu Krishna; Nygaard, Øystein Petter; Koju, Rajendra; Solligård, Erik (Journal article; Peer reviewed, 2018)
      Introduction Natural disasters pose a great challenge to the health systems and individual health facilities. In low-resource settings, disaster preparedness systems are often limited and not been well described. Two ...
    • Impact of baseline coronary flow and its distribution on Fractional Flow Reserve prediction 

      Muller, Lucas Omar; Fossan, Fredrik Eikeland; Bråten, Anders Tjellaug; Jørgensen, Arve; Wiseth, Rune; Hellevik, Leif Rune (Journal article; Peer reviewed, 2019)
      Model‐based prediction of fractional flow reserve (FFR) in the context of stable coronary artery disease (CAD) diagnosis requires a number of modelling assumptions. One of these assumptions is the definition of a baseline ...
    • Impact of different training modalities on high-density lipoprotein function in HFpEF patients: a substudy of the OptimEx trial 

      Sowa, Pamela W.; Winzer, Ephraim B.; Hommel, Jennifer; Männel, Anita; van Craenenbroeck, Emeline M.; Wisløff, Ulrik; Pieske, Burkert; Halle, Martin; Linke, Axel; Adams, Volker (Peer reviewed; Journal article, 2022)
      Aims In heart failure with preserved ejection fraction (HFpEF), the reduction of nitric oxide (NO)-bioavailability and consequently endothelial dysfunction leads to LV stiffness and diastolic dysfunction of the heart. ...
    • The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study 

      Jung, Christian; Flaatten, Hans; Fjølner, Jesper; Romano Bruno, Raphael; Wernly, Bernhard; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter Vernon; Szczeklik, Wojciech; Czuczwar, Miroslaw; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand (Peer reviewed; Journal article, 2021)
      Background The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in ...
    • Impact of Freezing Delay Time on Tissue Samples for Metabolomic Studies. 

      Haukaas, Tonje Husby; Moestue, Siver Andreas; Vettukattil, Muhammad Riyas; Sitter, Beathe; Lamichlane, Santosh; Segura, Reme; Giskeødegård, Guro F.; Bathen, Tone Frost (Journal article; Peer reviewed, 2016-01-28)
      Introduction: Metabolic profiling of intact tumor tissue by high-resolution magic angle spinning (HR MAS) MR spectroscopy (MRS) provides important biological information possibly useful for clinical diagnosis and development ...
    • Impact of Freezing Delay Time on Tissue Samples for Metabolomic Studies. 

      Haukaas, Tonje Husby; Moestue, Siver Andreas; Vettukattil, Muhammad Riyas; Sitter, Beathe; Lamichlane, Santosh; Segura, Reme; Giskeødegård, Guro F.; Bathen, Tone Frost (Journal article; Peer reviewed, 2016)
      Introduction: Metabolic profiling of intact tumor tissue by high-resolution magic angle spinning (HR MAS) MR spectroscopy (MRS) provides important biological information possibly useful for clinical diagnosis and development ...
    • Impact of strength training on the aging neuromuscular system 

      Unhjem, Runar Jakobsen (Doctoral theses at NTNU;2017:164, Doctoral thesis, 2017)
      Maximal muscle strength and rate of force development (RFD) decline with age. While this reduction has typically been attributed to muscle wasting, alterations in the nervous system are increasingly argued to be a ...
    • Impaired aerobic endurance and muscular strength in substance use disorder patients: implications for health and premature death 

      Flemmen, Grete; Wang, Eivind (Journal article; Peer reviewed, 2015)
      Abstract: Although substance use disorder (SUD) patients are documented to have an inactive lifestyle, which is associated with cardiovascular disease, other lifestyle-related diseases and premature death, evidence regarding ...
    • Impaired calcium handling in animal and human cardiomyocytes reduces contractility and increases arrhythmia potential: Effects of aerobic exercise training 

      Stølen, Tomas Ottemo (Doktoravhandlinger ved NTNU, 1503-8181; 2010:133, Doctoral thesis, 2010)
      Hjertesykdommer utgjør den største dødsårsaken i Europa. Hjertesvikt er endepunktet for hjertesykdommer, og det er estimert at omtrent 10 millioner mennesker har hjertesvikt i Europa. Omtrent 50% av dødsårsakene hos ...
    • Impaired right ventricular function in long-term survivors of allogeneic haematopoietic stem-cell transplantation 

      Massey, Richard; Diep, Phoi Phoi; Burman, Marta Maria; Kvaslerud, Anette Borger; Brinch, Lorentz; Aakhus, Svend; Gullestad, Lars; Ruud, Ellen; Beitnes, Jan Otto (Journal article; Peer reviewed, 2021)
      Aims Survivors of allogeneic haematopoietic stem-cell transplantation (allo-HSCT) are at higher risk of cardiovascular disease. We aimed to describe right ventricular (RV) systolic function and risk factors for RV dysfunction ...
    • Impaired skeletal health and neuromuscular function among amphetamine users in clinical treatment 

      Mosti, Mats Peder; Flemmen, Grete; Hoff, Jan; Stunes, Astrid Kamilla; Syversen, Unni; Wang, Eivind (Journal article; Peer reviewed, 2016)
      Summary This study examined musculoskeletal health in amphetamine users, compared with healthy age-matched controls. We show that amphetamine users have reduced bone mass at several skeletal sites and attenuated maximal ...
    • Implantasjon av hjertestartere ved St. Olavs hospital 2006–15 

      Nyman, Fred Mathias; Molaug, Ina Charlotte; Næss, Anne Marte; Espeland, Torvald; Loennechen, Jan Pål; Mjølstad, Ole Christian (Peer reviewed; Journal article, 2020)
      BAKGRUNN Implantasjon av hjertestarter (implantable cardioverter defibrillator, ICD) er etablert behandling hos pasienter med høy risiko for plutselig hjertedød. Studiens formål var å kartlegge pasientkarakteristika, ...
    • Implementing a Standardized Care Pathway Integrating Oncology, Palliative Care and Community Care in a Rural Region of Mid-Norway 

      Brenne, Anne-Tove; Løhre, Erik T; Knudsen, Anne Kari; Thronæs, Morten; Lund, Jo-Åsmund; Kongshaug, Nina; Neverdal, Marte Nilssen; Rystad, Kristina Edvardsen; Johansen, Marianne Haug; Braseth, Tone Inga; Kaasa, Stein (Peer reviewed; Journal article, 2021)
      Introduction To improve quality across levels of care, we developed a standardized care pathway (SCP) integrating palliative and oncology services for hospitalized and home-dwelling palliative cancer patients in a rural ...