Browsing Institutt for sirkulasjon og bildediagnostikk by Title
Now showing items 422-441 of 1934
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CYP2C19 – genvariant CYP2C19*17 og rask omsetting av legemidler
(Master thesis, 2011)Mutasjoner i genene som koder for CYP-enzymene med klinisk betydning, påvirker aktiviteten til enzymet. Doseringen av legemidler må tilpasses for å oppnå den ønskede responsen på legemiddelbehandlingen. Genet CYP2C19 koder ... -
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
(Peer reviewed; Journal article, 2023)Background Tocilizumab improves myocardial salvage index (MSI) in patients with ST-elevation myocardial infarction (STEMI), but its mechanisms of action are unclear. Here, we explored how cytokines were affected by tocilizumab ... -
Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond
(Peer reviewed; Journal article, 2021)Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity and fetal demands. We performed cytokine profiling of 1149 longitudinal serum ... -
Cytosolic phospholipase A2 alpha in aggressive breast cancer: Linking inflammation, angiogenesis, and metastasis
(Doctoral theses at NTNU;2018:340, Doctoral thesis, 2018) -
Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells
(Journal article; Peer reviewed, 2019)Metastatic disease is the leading cause of death in breast cancer patients. Disrupting the cancer cell’s ability to migrate may be a strategy for hindering metastasis. Cytosolic phospholipase A2 α (cPLA2α), along with ... -
Cytotoxicity and effect on wound re-epithelialization after topical administration of tranexamic acid
(Journal article; Peer reviewed, 2019)Background Topical administration of tranexamic acid (TXA) reduces bleeding from surgical wounds similarly to intravenous use, but with negligible risk of adverse systemic events. Topical use is expanding, but is ... -
Data acquisition for high resolution blood oxygen level dependent fMRI
(Doctoral theses at NTNU;2018:75, Doctoral thesis, 2018)Blood oxygen level dependent functional magnetic resonance imaging (BOLD fMRI) is an important non-invasive technique for investigation of brain function. Using BOLD fMRI, brain activity can be localized with high spatial ... -
Data Adaptive 2-D Tracking Doppler for High-Resolution Spectral Estimation
(Peer reviewed; Journal article, 2019)Spectral broadening in pulsed-wave Doppler caused by the transit-time effect deteriorates the frequency resolution and may cause overestimation of maximum velocities in high-velocity blood flow regions and for large ... -
Data from national health registers as endpoints for the Tromsø Study: Correctness and completeness of stroke diagnoses
(Peer reviewed; Journal article, 2021)Aim: To assess whether stroke diagnoses in national health registers are sufficiently correct and complete to replace manual collection of endpoint data for the Tromsø Study, a population-based epidemiological ... -
Deadly diving? Physiological and behavioural management of decompression stress in diving mammals
(Journal article; Peer reviewed, 2012)Decompression sickness (DCS; ‘the bends’) is a disease associated with gas uptake at pressure. The basic pathology and cause are relatively well known to human divers. Breath-hold diving marine mammals were thought to be ... -
Decidual and placental NOD1 is associated with inflammation in normal and preeclamptic pregnancies
(Peer reviewed; Journal article, 2021)Introduction: Inflammation is a normal physiological process that increases to harmful levels in preeclampsia. It affects the interaction between maternal immune cells and fetal trophoblasts at both sites of the maternal-fetal ... -
Decision support system and outcome prediction in a cohort of patients with necrotizing soft-tissue infections
(Peer reviewed; Journal article, 2022)Introduction: Necrotizing Soft Tissue Infections (NSTI) are severe infections with high mortality affecting a heterogeneous patient population. There is a need for a clinical decision support system which predicts ... -
Decision Tree Analyses for Prediction of QoL over a One-Year Period in Breast Cancer Patients: An Added Value of Patient-Reported Outcomes
(Peer reviewed; Journal article, 2023)Despite the current shift in medicine towards patient-centered care, clinicians rarely utilize patient-reported outcomes (PROs) in everyday practice. We examined the predictors of quality- of-life (QoL) trajectories in ... -
Deep Learning Applications for the Assessment of Valvular Heart Disease using Transthoracic Echocardiography
(Doctoral theses at NTNU;2024:198, Doctoral thesis, 2024)Valvular heart disease (VHD) is a class of diseases that affect the heart valves, and are associated with a reduced cardiac output and a poor prognosis for the afflicted patients. Transthoracic echocardiography (TTE) is ... -
Deep Learning Diffusion Parameters from Magnetic Resonance Imaging An Odyssey of Deep Learning IVIM Parameter Estimation
(Doctoral theses at NTNU;2024:148, Doctoral thesis, 2024)Cancer is a prominent cause of premature mortality worldwide and often preventable through early detection. Magnetic resonance imaging (MRI) is a vital modality in the investigation of many types of cancers, due to its ... -
Deep Learning for Improved Precision and Reproducibility of Left Ventricular Strain in Echocardiography: A Test-Retest Study
(Peer reviewed; Journal article, 2023)Aims Assessment of left ventricular (LV) function by echocardiography is hampered by modest test-retest reproducibility. A novel artificial intelligence (AI) method based on deep learning provides fully automated ... -
Deep Learning in the Echocardiography Workflow: Challenges and Opportunities
(Doctoral theses at NTNU;2023:390, Doctoral thesis, 2023)Echocardiography is the most widely used imaging technique for cardiac imaging due to its availability, low-cost and real-time capabilities. With numerous indicators of heart function, it now enables precise diagnosis of ... -
Defining the cut-off point of clinically significant postoperative fatigue in three common fatigue scales
(Journal article; Peer reviewed, 2018)Purpose Postoperative fatigue (POF) is an often underestimated problem after surgery. Studies on POF often report fatigue scores without relating this to the clinical relevance for the patients. The aim of this study was ... -
Deletion of Kinin B2 receptor alters muscle metabolism and exercise performance
(Journal article, 2015)Metabolic syndrome is a cluster of metabolic risk factors such as obesity, diabetes and cardiovascular diseases. Mitochondria is the main site of ATP production and its dysfunction leads to decreased oxidative phosphorylation, ... -
Demonstrating the Feasibility of Multimodal Neuroimaging Data Capture with a Wearable Electoencephalography + Functional Near-Infrared Spectroscopy (EEG+FNIRS) in Situ
(Peer reviewed; Journal article, 2021)We developed a wearable experimental sensor setup featuring multimodal EEG+fNIRS neuroimaging applicable for in situ experiments of human behavior in interaction with technology. A low-cost electroencephalography (EEG) was ...