• Mitochondrial genome-wide association study of migraine – the HUNT Study 

      Børte, Sigrid; Zwart, John-Anker; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Thomas, Laurent; Fritsche, Lars G; Surakke, Ida; Nielsen, Jonas B.; Zhou, Wei; Wolford, Brooke; Vigeland, Magnus Dehli; Hagen, Knut; Kristoffersen, Espen Saxhaug; Nyholt, Dale R; Chasman, Daniel I; Brumpton, Ben Michael; Willer, Christen; Winsvold, Bendik K S (Peer reviewed; Journal article, 2020)
      Background Variation in mitochondrial DNA (mtDNA) has been indicated in migraine pathogenesis, but genetic studies to date have focused on candidate variants, with sparse findings. We aimed to perform the first mitochondrial ...
    • Mixed evidence for the relationship between periodontitis and Alzheimer’s disease: A bidirectional Mendelian randomization study 

      Sun, Yi-Qian; Richmond, Rebecca C.; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2020)
      Recent experimental studies indicated that a periodontitis-causing bacterium might be a causal factor for Alzheimer’s disease (AD). We applied a two-sample Mendelian randomization (MR) approach to examine the potential ...
    • Model-based assessment of replicability for genome-wide association meta-analysis 

      McGuire, Daniel; Jiang, Yu; Liu, Mengzhen; Weissenkampen, J. Dylan; Eckert, Scott; Yang, Lina; Chen, Fang; Liu, MengZhen; Wedow, Robbee; Li, Yue; Brazel, David M.; Datta, Gargi; Davila-Velderrain, Jose; Tian, Chao; Zhan, Xiaowei; Choquet, H. éléne; Docherty, Anna R.; Faul, Jessica D.; Foerster, Johanna R.; Fritsche, Lars; Gabrielsen, Maiken Elvestad; Gordon, Scott D.; Haessler, Jeffrey; Hottenga, Jouke-Jan; Huang, Hongyan; Jang, Seon-Kyeong; Jansen, Philip R.; Ling, Yueh; Ma ̈gi, Reedik; Matoba, Nana; McMahon, George; Mulas, Antonella; Orru, Valeria; Palviainen, Teemu; Pandit, Anita; Reginsson, Gunnar W.; Skogholt, Anne Heidi; Smith, Jennifer A.; Taylor, Amy E.; Turman, Constance; Willemsen, Gonneke; Young, Hannah; Young, Kendra A.; Zajac, Gregory J. M.; Zhao, Wei; Zhou, Wei; Bjornsdottir, Gyda; Boardman, Jason D.; Boehnke, Michael; Boomsma, Dorret I.; Chen, Chu; Cucca, Francesco; Davies, Gareth E.; Eaton, Charles B.; Ehringer, Marissa A.; Esko, Tõnu; Fiorillo, Edoardo; Gillespie, Nathan A.; Gudbjartsson, Daniel F.; Haller, Toomas; Harris, Kathleen Mullan; Heath, Andrew C.; Hewitt, John K.; Hickie, Ian B.; Hokanson, John E.; Hopfer, Christian J.; Hunter, David J.; Iacono, William G.; Johnson, Eric O.; Kamatani, Yoichiro; Kardia, Sharon L. R.; Keller, Matthew C.; Kellis, Manolis; Kooperberg, Charles; Kraft, Peter; Krauter, Kenneth S.; Laakso, Markku; Lind, Penelope A.; Loukola, Anu; Lutz, Sharon M.; Madden, Pamela A. F.; Martin, Nicholas G.; McGue, Matt; McQueen, Matthew B.; Medland, Sarah E.; Metspalu, Andres; Mohlke, Karen L.; Nielsen, Jonas B.; Okada, Yukinori; Peters, Ulrike; Polderman, Tinca J. C.; Posthuma, Danielle; Reiner, Alexander P.; Rice, JP; Rimm, Eric; Rose, Richard J.; Runarsdottir, Valgerdur; Stallings, Michael C.; Stanˇca ́kova, Alena; Stefansson, Hreinn; Thai, Khanh K.; Tindle, Hilary A.; Tyrfingsson, Thorarinn; Wall, Tamara L.; Weir, David R.; Weisner, Constance M; Whitfield, John B.; Winsvold, Bendik K S; Yin, Jie; Zuccolo, Luisa; Bierut, Laura J.; Hveem, Kristian; Lee, James J.; Munafo, Marcus R.; Saccone, Nancy L.; Willer, Cristen J; Cornelis, Marilyn C.; David, Sean P.; Hinds, David; Jorgenson, Eric; Kaprio, Jaakko; Stitzel, Jerry A.; Stefansson, Kari; Thorgeirsson, Thorgeir E.; Abecasis, Goncalo; Liu, Dajiang J.; Vrieze, Scott; Berg, Arthur; Jiang, Bibo; Li, Qunhua (Peer reviewed; Journal article, 2021)
      Genome-wide association meta-analysis (GWAMA) is an effective approach to enlarge sample sizes and empower the discovery of novel associations between genotype and phenotype. Independent replication has been used as a ...
    • ModelExplorer - software for visual inspection and inconsistency correction of genome-scale metabolic reconstructions 

      Martyushenko, Nikolay; Almaas, Eivind (Journal article; Peer reviewed, 2019)
      Background Genome-scale metabolic network reconstructions are low level chemical representations of biological organisms. These models allow the system-level investigation of metabolic phenotypes using a variety of ...
    • Modeling Obesity in Norway (The MOON Study): A Decision-Analytic Approach—Prevalence, Costs, and Years of Life Lost 

      Bjørnelv, Gudrun Maria Waaler; Halsteinli, Vidar; Kulseng, Bård Eirik; Sonntag, Diana; Ødegård, Rønnaug (Peer reviewed; Journal article, 2020)
      Background. Limited knowledge exists on the expected long-term effects and cost-effectiveness of initiatives aiming to reduce the burden of obesity. Aim. To develop a Norwegian obesity-focused disease-simulation model: the ...
    • Modelling PCB-153 in northern ecosystems across time, space, and species using the nested exposure model 

      Krogseth, Ingjerd Sunde; Breivik, Knut; Frantzen, Sylvia; Nilsen, Bente Merete; Eckhardt, Sabine; Nøst, Therese Haugdahl; Wania, Frank (Peer reviewed; Journal article, 2023)
      There is concern over possible effects on ecosystems and humans from exposure to persistent organic pollutants (POPs) and chemicals with similar properties. The main objective of this study was to develop, evaluate, and ...
    • Modelling Similarity for Comparing Physical Activity Profiles - A Data-Driven Approach 

      Verma, Deepika; Bach, Kerstin; Mork, Paul Jarle (Journal article; Peer reviewed, 2018)
      Objective measurements of physical behaviour are an interesting research field from the public health and computer science perspective. While for public health research, measurements with a high quality and feasible setup ...
    • Modelling study to estimate the health burden of foodborne diseases: Cases, general practice consultations and hospitalisations in the UK, 2009 

      O'Brien, Sarah J; Larose, Tricia L; Adak, Goutam K; Evans, Meirion R; Tam, Clarence C (Journal article; Peer reviewed, 2016)
      Objective To generate estimates of the burden of UK-acquired foodborne disease accounting for uncertainty. Design A modelling study combining data from national public health surveillance systems for laboratory-confirmed ...
    • Modelling the concentration of chloroform in the air of a Norwegian swimming pool facility-A repeated measures study 

      Nitter, Therese Bergh; Svendsen, Kristin V Hirsch (Journal article; Peer reviewed, 2019)
      Certain volatile disinfection by-products (DBPs) off-gassing from pool water can cause eye and skin irritations, respiratory problems, and even cancer. No guidelines or recommendations concerning DBPs in the air exist in ...
    • Moderate and severe traumatic brain injury in general hospitals: a ten-year population-based retrospective cohort study in central Norway 

      Rahim, Shavin; Laugsand, Eivor Alette; Fyllingen, Even Hovig; Rao, Vidar; Pantelatos, Rabea Iris; Müller, Tomm Brostrup; Vik, Anne; Skandsen, Toril (Peer reviewed; Journal article, 2022)
      Background Patients with moderate and severe traumatic brain injury (TBI) are admitted to general hospitals (GHs) without neurosurgical services, but few studies have addressed the management of these patients. This ...
    • Moderate traumatic brain injury - the acute phase 

      Lund, Stine Borgen (Master thesis, 2012)
      Background and aim: Patients with moderate traumatic brain injury (TBI) have variability in the acute phase course and long-term outcome. Research is limited and often inconclusive. The aim was to study intensive care ...
    • Moderate traumatic brain injury: Clinical characteristics and a prognostic model of 12-month outcome 

      Einarsen, Cathrine Elisabeth; van der Naalt, Joukje; Jacobs, Bram; Follestad, Turid; Moen, Kent Gøran; Vik, Anne; Håberg, Asta; Skandsen, Toril (Journal article; Peer reviewed, 2018)
      BACKGROUND:Patients with moderate traumatic braininjury (TBI) often are studied together with patients withsevere TBI, even though the expected outcome of theformer is better. Therefore, we aimed to describe patientcharacteristics ...
    • Moderately increased albuminuria, chronic kidney disease and incident dementia: the HUNT study 

      Gabin, Jessica Mira; Romundstad, Solfrid; Saltvedt, Ingvild; Holmen, Jostein (Journal article; Peer reviewed, 2019)
      Background Epidemiologic studies has shown an association of albuminuria and low estimated glomerular filtration rate (eGFR) with dementia, but the findings are inconsistent. This study examines the association between ...
    • Modern mammography screening and breast cancer mortality: Population study 

      Weedon-Fekjær, Harald; Romundstad, Pål Richard; Vatten, Lars Johan (Journal article, 2014)
      Objective: To evaluate the effectiveness of contemporary mammography screening using individual information about screening history and breast cancer mortality from public screening programmes. Design: Prospective cohort ...
    • Modified prolonged exposure therapy as Early Intervention after Rape (The EIR-study): study protocol for a multicenter randomized add-on superiority trial 

      Haugen, Tina; Halvorsen, Joar Øveraas; Friborg, Oddgeir; Simpson, Melanie Rae; Mork, Paul Jarle; Mikkelsen, Gustav; Elklit, Ask; Rothbaum, Barbara O.; Schei, Berit; Hagemann, Cecilie Therese (Peer reviewed; Journal article, 2023)
      Background Sexual assault and rape are the traumatic life events with the highest probability for posttraumatic stress disorder (PTSD), which can have devastating consequences for those afflicted by the condition. Studies ...
    • Molecular subtypes of breast cancer: incidence and prognosis 

      Valla, Marit (Doctoral theses at NTNU;2017:276, Doctoral thesis, 2017)
      Forekomsten av brystkreft har over flere tiår økt i den vestlige verden, og i Norge har det vært en dobling av insidensen siden Kreftregisteret startet sin overvåkning av antall krefttilfeller i Norge i 1952. I Norge har ...
    • Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences 

      Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe (Journal article; Peer reviewed, 2016)
      Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of 52,949 ...
    • Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients 

      Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. (Peer reviewed; Journal article, 2013)
      Molecular subtyping of breast cancer may provide additional prognostic information regarding patient outcome. However, its clinical significance remains to be established. In this study, the main aims were to discover ...