Blar i Institutt for klinisk og molekylær medisin på emneord "VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750"
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An investigation of potential variables affecting the physiological adaptations to weight loss: weight loss rate, nature of energy restriction, and ketosis
(Doctoral theses at NTNU;2018:53, Doctoral thesis, 2018)Various reviews published over the last decades have shown that several compensatory responses on both sides of the energy balance (EB) equation are activated with weight loss (WL), which oppose the maintenance of a reduced ... -
Appetite in obesity and subsequent effects of weight loss induced by dietary restriction alone or combined with bariatric surgery
(Doctoral theses at NTNU;2023:71, Doctoral thesis, 2023) -
Awareness of hypoglycemia in type 1 diabetes - On the assessment, prevalence, and clinical associations of impaired awareness of hypoglycemia in children and adults
(Doctoral theses at NTNU;2023:408, Doctoral thesis, 2023)Over one hundred years after the first doses of insulin were given as treatment for type 1 diabetes (TlD), hypoglycemia is still the main factor limiting optimal blood glucose control. Episodes of hypoglycemia are by itself ... -
Cancer induced bone pain
(Doctoral theses at NTNU;2024:38, Doctoral thesis, 2024)Bone metastases causing cancer induced bone pain (CIBP) is one of the most frequent reasons for pain in patients with cancer. Although pain is a common consequence of bone metastases, not all patients with bone metastases ... -
Chemotherapy for colorectal cancer - Physical exercise and quality of life
(Doctoral theses at NTNU;2024:34, Doctoral thesis, 2024)Colorectal cancer (CRC) is the third most common cancer worldwide, the second most common cancer in Norway, and the second leading cause of cancer deaths both globally and nationally. In Norway, 4745 new cases were diagnosed ... -
Circulating calprotectin: from measurement to clinical application - studies of preanalytical, analytical, and cardiovascular biomarker performance
(Doctoral theses at NTNU;2024:161, Doctoral thesis, 2024)Norsk sammendrag Hjerte-karsykdom er en svært vanlig årsak til sykdom og tidlig død på verdensbasis og skyldes i hovedsak åreforkalkning (aterosklerose) som oppstår pga. fettavleiringer og inflammasjon i åreveggene. ... -
Clinical Aspects in Translational Research on Gastric Tumorigenesis and Development of New Treatments
(Doctoral theses at NTNU;2023:360, Doctoral thesis, 2023)Kliniske aspekter ved translasjonsforskning på magekreft og utvikling av nye behandlinger Bakgrunn/mål: Medisinsk translasjonsforskning er en toveis prosess for å redusere avstanden fra laboratoriet til sykesengen ved å ... -
Cognitive function during disease progression in a rat model of Alzheimer’s disease - Effect of a single bout of exhaustive aerobic exercise
(Master thesis, 2018)Alzheimer’s disease (AD), the most prevalent form of dementia, is a devastating neurodegenerative disorder affecting over 35 million people worldwide. As age is the main risk factor for AD, and no current treatment options ... -
Contribution of Autopsy, Placental Examination and Molecular Techniques in Explaining Fetal Death
(Doctoral theses at NTNU;2018:121, Doctoral thesis, 2018)Summary in Norwegian Bakgrunn I Norge ender 3,6 av 1000 svangerskap med dødfødsel (Medisinsk fødselsregister, 2015). Et betydelig antall fosterdødsfall forblir uforklart. Målet med denne studien var å kategorisere ... -
Cytokine profiling as a measure of immunological development and deviation throughout pregnancy in healthy women and women with PCOS
(Doctoral theses at NTNU;2022:183, Doctoral thesis, 2022)Norsk sammendrag Cytokinprofilering som mål på immunologiske forandringer gjennom svangerskapet hos friske kvinner og kvinner med PCOS Mors immunsystem tilpasser seg gjennom de ulike fasene av svangerskapet for å sikre ... -
Depression in palliative care cancer patients - Assessment and classification
(Doctoral theses at NTNU;2018:12, Doctoral thesis, 2018)Palliative care aims at improving quality of life and reducing suffering in patients with lifethreatening illness through the early identification, assessment and treatment of problems. Depression reduces quality of life ... -
Development of an improved pathway analysis - The FunHop story
(Doctoral theses at NTNU;2022:212, Doctoral thesis, 2022)Norsk sammendrag Arbeidet som presenteres i denne avhandlingen omhandler metabolisme i prostatakreft, hovedsakelig i form av bruk og forbedring av analyse av biologiske spor. En stor del av oppgaven handler om utvikling ... -
Developmental Origins of Disease: Influence of low birth weight and maternal vitamin A and D status on offspring skeletal health and metabolic outcomes at adulthood
(Doctoral theses at NTNU;2018:221, Doctoral thesis, 2018)Developmental origins of adult health and disease (DOHaD) has gained increased attention during the past few decades. Birth size reflects the prenatal environment, and there is substantial evidence that low birth weight ... -
ErbB receptors in human meningiomas
(Doctoral theses at NTNU;2019:183, Doctoral thesis, 2019)Background: Meningiomas are the most common intracranial tumors in adults. They originate in the meninges, can grow to substantial size, and are in most cases benign. Recurrence; however, frequently occurs regardless of ... -
Evaluation of Neoadjuvant Chemotherapy in Patients with Resectable Gastric Adenocarcinoma in Central Norway 2007 – 2016
(Doctoral theses at NTNU;2024:12, Doctoral thesis, 2024)This thesis presents three retrospective, population-based, observational studies on patients diagnosed with upfront resectable gastric adenocarcinoma and receiving neoadjuvant chemotherapy (NAC) in Central Norway during ... -
Falls during index hospital stay and reoperations due to falls in lower limb amputees
(Master thesis, 2017)Background and purpose: Major lower limb amputations (MLLA) is here defined as an amputation above the ankle. Such amputations are most often performed due to ischemia, osteomyelitis and trauma. The objective of this study ... -
Gynecological complaints and management of women subjected to female genital mutilation - A descriptive study among women attending a university hospital in Norway
(Master thesis, 2017)Abstract Background Female genital mutilation (FGM) is a harmful traditional practice comprising procedures involving partial or total removal of external female genitalia and/or narrowing of the vaginal orifice for ... -
High-grade digestive neuroendocrine neoplasms. Impact of genetic alterations and morphologicalcharacteristics on outcome of first-line palliative chemotherapy
(Doctoral theses at NTNU;2023:353, Doctoral thesis, 2023)Høygradige nevroendokrine neoplasmer i fordøyelsessystemet. Innvirkninger av genforandringer på behandlingseffekt og overlevelse. Høygradige nevroendokrine neoplasmer (HG-NEN) utgående fra fordøyelsessystemet er en kreft ... -
HIV infection of CD4+ T cells: New insights into innate sensing and host dependency factors
(Doctoral theses at NTNU;2018:261, Doctoral thesis, 2018)Despite decades of research and public health efforts, HIV/AIDS remains a major global health issue with more than 36 million people infected with the virus in 2016. Effective HIV treatment has enabled HIV infected patients ... -
Humoral immunity and revaccination in childhood cancer
(Master thesis, 2017)Background: Chemotherapy treatment for childhood cancer impair the cellular and humoral immune system in various degrees and affects the previous protection of childhood vaccination. Studies have shown protective antibody ...